Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Michael A, Helmrath"'
Autor:
Jayati Chakrabarti, Martha Dua-Awereh, Michael Schumacher, Amy Engevik, Jennifer Hawkins, Michael A. Helmrath, Yana Zavros
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-16 (2022)
Abstract Sonic Hedgehog (Shh), secreted from gastric parietal cells, contributes to the regeneration of the epithelium. The recruitment of macrophages plays a central role in the regenerative process. The mechanism that regulates macrophage recruitme
Externí odkaz:
https://doaj.org/article/ad3184e2b8914b3d8cdcaef72809f861
Autor:
Heather A. McCauley, Andrea L. Matthis, Jacob R. Enriquez, Jonah T. Nichol, J. Guillermo Sanchez, William J. Stone, Nambirajan Sundaram, Michael A. Helmrath, Marshall H. Montrose, Eitaro Aihara, James M. Wells
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Enteroendocrine cells (EECs) are specialized gastrointestinal cells that have a role in nutrient sensing and hormone secretion. Here the authors show that peptide YY from EECs regulates nutrient absorption in intestinal organoids.
Externí odkaz:
https://doaj.org/article/50edefa8b4244558bced763cdc66baa9
Autor:
Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipoc
Externí odkaz:
https://doaj.org/article/d7769e000a41416a858c145b467956f7
Autor:
Suman Pradhan, Sayali S. Karve, Alison A. Weiss, Jennifer Hawkins, Holly M. Poling, Michael A. Helmrath, James M. Wells, Heather A. McCauley
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 171-190 (2020)
Background & Aims: Shiga toxin (Stx)-producing Escherichia coli (eg, O157:H7) infection produces bloody diarrhea, while Stx inhibits protein synthesis and causes the life-threatening systemic complication of hemolytic uremic syndrome. The murine inte
Externí odkaz:
https://doaj.org/article/6bbfdf62ec0b4631968dc0990ad90901
Autor:
Kristen J Nadeau, Andrew T Trout, Amy S Shah, Michael A Helmrath, Thomas H Inge, Stavra A Xanthakos, Megan M Kelsey, Todd Jenkins, Lorna Browne
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Introduction The pathophysiology of type 2 diabetes (T2D) in youth differs from adults and conventional medical treatment approaches with lifestyle change, metformin, thiazolidinediones or insulin are inadequate. Metabolic bariatric surgery (MBS) imp
Externí odkaz:
https://doaj.org/article/0fd6a9dc08254b6698fdaa24b7298bdc
Autor:
Meg H. Zeller, Heather Strong, Jennifer Reiter-Purtill, Todd M. Jenkins, James E. Mitchell, Marc P. Michalsky, Michael A. Helmrath
Publikováno v:
Surgery for Obesity and Related Diseases. 19:512-521
The postoperative course after pediatric metabolic and bariatric surgery (MBS) cuts across a developmental phase when substance-use behaviors emerge as significant public health concerns.We examined use of marijuana, conventional cigarettes, and alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a915713dee75906b429cd0be5415efe7
https://doi.org/10.1016/j.soard.2022.11.008
https://doi.org/10.1016/j.soard.2022.11.008
Autor:
John P. Marquart, Alexis N Bowder, Christina M. Bence, Shawn D. St. Peter, Samir K. Gadepalli, Thomas T. Sato, Aniko Szabo, Peter C. Minneci, Ronald B. Hirschl, Beth A. Rymeski, Cynthia D. Downard, Troy A. Markel, Katherine J. Deans, Mary E. Fallat, Jason D. Fraser, Julia E. Grabowski, Michael A. Helmrath, Rashmi D. Kabre, Jonathan E. Kohler, Matthew P. Landman, Amy E. Lawrence, Charles M. Leys, Grace Z. Mak, Elissa Port, Jacqueline Saito, Jared Silverberg, Mark B. Slidell, Tiffany N. Wright, Dave R. Lal
Publikováno v:
Journal of Pediatric Surgery. 58:27-33
Controversy persists regarding the ideal surgical approach for repair of esophageal atresia with tracheoesophageal fistula (EA/TEF). We examined complications and outcomes of infants undergoing thoracoscopy and thoracotomy for repair of Type C EA/TEF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab81eeb4680f2459f546254583360434
https://doi.org/10.1016/j.jpedsurg.2022.09.015
https://doi.org/10.1016/j.jpedsurg.2022.09.015
Autor:
Akaljot Singh, Holly M Poling, Nambirajan Sundaram, Nicole Brown, James M Wells, Michael A Helmrath
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237885 (2020)
Our group has developed two transplantation models for the engraftment of Human Intestinal Organoids (HIOs): the renal subcapsular space (RSS) and the mesentery each with specific benefits for study. While engraftment at both sites generates laminate
Externí odkaz:
https://doaj.org/article/4df5319f91e4406ea55d08281fbc7442
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 2, Pp 149-162 (2018)
Short-bowel syndrome represents the most common cause of intestinal failure and occurs when the remaining intestine cannot support fluid and nutrient needs to sustain adequate physiology and development without the use of supplemental parenteral nutr
Externí odkaz:
https://doaj.org/article/a9d2bfde6a3d42d4a678ce5dc2edaed1
Autor:
Kodandaramireddy Nalapareddy, Kalpana J. Nattamai, Rupali S. Kumar, Rebekah Karns, Kathryn A. Wikenheiser-Brokamp, Leesa L. Sampson, Maxime M. Mahe, Nambirajan Sundaram, Mary-Beth Yacyshyn, Bruce Yacyshyn, Michael A. Helmrath, Yi Zheng, Hartmut Geiger
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2608-2621 (2017)
Although intestinal homeostasis is maintained by intestinal stem cells (ISCs), regeneration is impaired upon aging. Here, we first uncover changes in intestinal architecture, cell number, and cell composition upon aging. Second, we identify a decline
Externí odkaz:
https://doaj.org/article/c6980a428dc64392a7a39bc4956b9d03