Efficacy and Safety of Trastuzumab as a Single Agent in First-Line Treatment of HER2-Overexpressing Metastatic Breast Cancer

Autor: Charles L, Vogel, Melody A, Cobleigh, Debu, Tripathy, John C, Gutheil, Lyndsay N, Harris, Louis, Fehrenbacher, Dennis J, Slamon, Maureen, Murphy, William F, Novotny, Michael, Burchmore, Steven, Shak, Stanford J, Stewart, Michael, Press

Publikováno v: Journal of Clinical Oncology. 41:1638-1645

PURPOSE To evaluate the efficacy and safety of first-line, single-agent trastuzumab in women with HER2-overexpressing metastatic breast cancer. PATIENTS AND METHODS One hundred fourteen women with HER2-overexpressing metastatic breast cancer were ran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbad728710b584bef814c355e69a2d35
https://doi.org/10.1200/jco.22.02516

Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials

Autor: Rosie Bradley, Jeremy Braybrooke, Richard Gray, Robert Hills, Zulian Liu, Richard Peto, Lucy Davies, David Dodwell, Paul McGale, Hongchao Pan, Carolyn Taylor, Stewart Anderson, Richard Gelber, Luca Gianni, William Jacot, Heikki Joensuu, Alvaro Moreno-Aspitia, Martine Piccart, Michael Press, Edward Romond, Dennis Slamon, Vera Suman, Richard Berry, Clare Boddington, Mike Clarke, Christina Davies, Fran Duane, Vaughan Evans, Jo Gay, Lucy Gettins, Jon Godwin, Sam James, Hui Liu, Elizabeth MacKinnon, Gurdeep Mannu, Theresa McHugh, Philip Morris, Simon Read, Ewan Straiton, Yaochen Wang, John Crown, Evandro de Azambuja, Suzette Delaloge, Helena Fung, Charles Geyer, Marc Spielmann, Pinuccia Valagussa, Kathy Albain, Rodrigo Arriagada, John Bartlett, Elizabeth Bergsten-Nordström, Judith Bliss, Etienne Brain, Lisa Carey, Robert Coleman, Jack Cuzick, Nancy Davidson, Lucia Del Mastro, Angelo Di Leo, James Dignam, Mitch Dowsett, Bent Ejlertsen, Prue Francis, Michael Gnant, Matthew Goetz, Pam Goodwin, Pat Halpin-Murphy, Dan Hayes, Catherine Hill, Reshma Jagsi, Wolfgang Janni, Sibylle Loibl, Eleftherios P Mamounas, Miguel Martín, Hirofumi Mukai, Valentina Nekljudova, Larry Norton, Yasuo Ohashi, Lori Pierce, Philip Poortmans, Vinod Raina, Daniel Rea, Meredith Regan, John Robertson, Emiel Rutgers, Tanja Spanic, Joseph Sparano, Guenther Steger, Gong Tang, Masakazu Toi, Andrew Tutt, Giuseppe Viale, Xiang Wang, Tim Whelan, Nicholas Wilcken, Norman Wolmark, David Cameron, Jonas Bergh, Kathleen I Pritchard, Sandra M Swain

Publikováno v: The Lancet. Oncology
The lancet oncology
Early Breast Cancer Trialists’ Collaborative group (EBCTCG) 2021, ' Trastuzumab for early-stage, HER2-positive breast cancer : a meta-analysis of 13 864 women in seven randomised trials ', The Lancet Oncology, vol. 22, no. 8, pp. 1139-1150 . https://doi.org/10.1016/S1470-2045(21)00288-6

Background: Trastuzumab targets the extracellular domain of the HER2 protein. Adding trastuzumab to chemotherapy for patients with early-stage, HER2-positive breast cancer reduces the risk of recurrence and death, but is associated with cardiac toxic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82494828596b0011685b9eb25b23e93
http://europepmc.org/articles/PMC8324484

Review of Michael Press, 2020, Salvation in Melanesia: Becoming a New Person in Churches in Fiji and Papua New Guinea, Lanham: Lexington Books/Fortress Academic

Autor: Jaap Timmer

Publikováno v: Aarhus University
Timmer, J 2022, ' Review of Michael Press, 2020, Salvation in Melanesia: Becoming a New Person in Churches in Fiji and Papua New Guinea, Lanham: Lexington Books/Fortress Academic. ', Pacific Affairs, vol. 95, no. 2 . < https://pacificaffairs.ubc.ca/book-reviews/salvation-in-melanesia-becoming-a-new-person-in-churches-in-fiji-and-papua-new-guinea-by-michael-press/ >

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::46b4addd1df524d92ee9970b550627af
https://pure.au.dk/portal/en/publications/review-of-michael-press-2020-salvation-in-melanesia-becoming-a-new-person-in-churches-in-fiji-and-papua-new-guinea-lanham-lexington-booksfortress-academic(8ef0105b-ade4-41e2-bdf7-915b8f929948).html

Jump Start

Autor: Michael Press

Focusing on the combined task of our mind and body, together with social and historical aspects, understanding who we are seems to be an ever-challenging task. With the rise of technology and time constraints, lifestyle activities and even gaps in so

HER2 Testing in the Era of Changing Guidelines

Autor: Mahdi Khoshchehreh, Grace Namjung Kim, Dennis J. Slamon, Michael Press, Yanling Ma

Publikováno v: Her2-Positive Breast Cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa27f8fe7ce21a931ef527c72b0f5092
https://doi.org/10.1016/b978-0-323-58122-6.00002-7