Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Michael Guilhaus"'
Publikováno v:
Rapid Communications in Mass Spectrometry. 29:91-99
RATIONALE Mass spectrometric identification of compounds in chromatography can be obtained from molecular masses from soft ionization mass spectrometry techniques such as field ionization (FI) and fragmentation patterns from hard ionization technique
Autor:
Jonathon R Davey, Sean J. Humphrey, Robert T. Lawrence, Carol Kistler, Jamie Soul, Robert G. Parton, David E. James, James G. Burchfield, Penelope J. La-Borde, Mark Larance, Matthew J. Prior, Michael Guilhaus, Michael Buckley, Hiroshi Kanazawa
Publikováno v:
Journal of Proteome Research. 10:4970-4982
The adipocyte is a key regulator of mammalian metabolism. To advance our understanding of this important cell, we have used quantitative proteomics to define the protein composition of the adipocyte plasma membrane (PM) in the presence and absence of
Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion
Autor:
Michael Guilhaus, Alessandra Warren, Anne Poljak, Jeremy S. Wilson, Phoebe A. Phillips, Lu Yang, Sonia Bustamante, Romano C. Pirola, Minoti V. Apte, Arthur Shulkes, Zhihong Xu, Alain Vonlaufen
Publikováno v:
Proceedings of the National Academy of Sciences. 107:17397-17402
The pancreatic secretagogue cholecystokinin (CCK) is widely thought to stimulate enzyme secretion by acinar cells indirectly via activation of the vagus nerve. We postulate an alternative pathway for CCK-induced pancreatic secretion. We hypothesize t
Publikováno v:
Diabetes
OBJECTIVE Visceral adipose tissue (VAT) is more closely linked to insulin resistance than subcutaneous adipose tissue (SAT). We conducted a quantitative analysis of the secretomes of VAT and SAT to identify differences in adipokine secretion that acc
Publikováno v:
Macromolecular Chemistry and Physics. 211:520-528
Size exclusion chromatography coupled online to electrospray ionization mass spectrometry (SEC/ESI-MS) is employed to establish universal calibration (UC) relationships for a number of linear poly(alkyl acrylates) and poly(alkyl methacrylates) (pMMAs
Publikováno v:
Macromolecular Chemistry and Physics. 211:80-90
Pulsed laser polymerization (PLP) in conjunction with online size exclusion chromatography electrospray ionization mass spectrometry (SEC/ESI-MS) has successfully been applied for the determination of accurate propagation rate coefficients, kp, in fr
Autor:
Dominic Burg, Michael Guilhaus, Mark J. Raftery, Federico M. Lauro, Ricardo Cavicchioli, Timothy J. Williams
Publikováno v:
Journal of Proteome Research. 9:664-676
Proteomic studies have proven useful for studying the Antarctic archaeon Methanococcoides burtonii; however, little has been learned about the hydrophobic and membrane proteins, despite knowledge of their biological importance. In this study, new met
Autor:
Lily Ting, Mark J. Raftery, Ricardo Cavicchioli, Mark J. Cowley, Michael Guilhaus, Seah Lay Hoon
Publikováno v:
Molecular & Cellular Proteomics. 8:2227-2242
Comparative proteomics is a powerful analytical method for learning about the responses of biological systems to changes in growth parameters. To make confident inferences about biological responses, proteomics approaches must incorporate appropriate
Publikováno v:
Macromolecules. 42:6366-6374
We present a method to determine accurate and absolute molecular weight distributions (MWDs) as well as absolute concentrations of the individual macromolecular components in mixtures of polymers of the same monomer class yet differing in their end g
Publikováno v:
Rapid Communications in Mass Spectrometry. 23:2181-2189
Orthogonal acceleration time-of-flight (oa-TOF) mass spectrometry (MS) was coupled to gas chromatography (GC) to measure ion yields (ratio of ion counts to number of neutrals entering the ion source) and signal-to-noise (S/N) in the electron ionizati