Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Michael D. Best"'
Autor:
Yue Zhou, Gregory A. Phelps, Mikayla M. Mangrum, Jemma McLeish, Elise K. Phillips, Jinchao Lou, Christelle F. Ancajas, Jeffrey M. Rybak, Peter M. Oelkers, Richard E. Lee, Michael D. Best, Todd B. Reynolds
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTSystemic infections by Candida spp. are associated with high mortality rates, partly due to limitations in current antifungals, highlighting the need for novel drugs and drug targets. The fungal phosphatidylserine synthase, Cho1, from Candida
Externí odkaz:
https://doaj.org/article/78c37e13beb64762ba0868b9367af010
Autor:
Christelle F. Ancajas, Shahrina Alam, Daiane S. Alves, Yue Zhou, Nicholas M. Wadsworth, Chelsi D. Cassilly, Tanei J. Ricks, Adam J. Carr, Todd B. Reynolds, Francisco N. Barrera, Michael D. Best
Publikováno v:
ACS Chemical Biology. 18:377-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcfad1bb19441877b7bc6f2f59c28a95
https://doi.org/10.1021/acschembio.2c00813
https://doi.org/10.1021/acschembio.2c00813
Harnessing Clickable Acylated Glycerol Probes as Chemical Tools for Tracking Glycerolipid Metabolism
Autor:
Christelle F. Ancajas, Adam J. Carr, Jinchao Lou, Ruhani Sagar, Yue Zhou, Todd B. Reynolds, Michael D. Best
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92fcdbc7954e604c64daf2b0870f4c0d
https://doi.org/10.1002/chem.202300417
https://doi.org/10.1002/chem.202300417
Autor:
Richard K. Fisher, Phillip C. West, Samuel I. Mattern-Schain, Michael D. Best, Stacy S. Kirkpatrick, Raymond A. Dieter, Joshua D. Arnold, Michael R. Buckley, Michael M. McNally, Michael B. Freeman, Oscar H. Grandas, Deidra J. H. Mountain
Publikováno v:
Nanomaterials, Vol 11, Iss 3, p 825 (2021)
Lipid nanoparticles have become increasingly popular delivery platforms in the field of gene therapy, but bench-to-bedside success has been limited. Many liposomal gene vectors are comprised of synthetic cationic lipids, which are associated with lip
Externí odkaz:
https://doaj.org/article/417343aefefb4e48ab74582144011023
Publikováno v:
Organicbiomolecular chemistry.
In this work, we report triggered content release from liposomes brought about by copper chelation to a synthetic lipid switch containing a picolinamide headgroup. Fluorescence-based dye-leakage assays showcase release of carboxyfluorescein dye cargo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b64e24384421cce2def1ce6be3a1ff
https://pubmed.ncbi.nlm.nih.gov/36622111
https://pubmed.ncbi.nlm.nih.gov/36622111
Publikováno v:
Chembiochem : a European journal of chemical biology.
Liposomes are highly effective nanocarriers for encapsulating and delivering a wide range of therapeutic cargo. While advancements in liposome design have improved several pharmacological characteristics, an important area that would benefit from fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfa4c25fe973c6d9d04fb363c0f7ff1
https://pubmed.ncbi.nlm.nih.gov/36164720
https://pubmed.ncbi.nlm.nih.gov/36164720
Autor:
Megan L. Qualls, Hannah Hagewood, Jinchao Lou, Samuel I. Mattern‐Schain, Xiaoyu Zhang, Deidra J. Mountain, Michael D. Best
Publikováno v:
ChemBioChem. 23
Liposomes are effective therapeutic nanocarriers due to their ability to encapsulate and enhance the pharmacokinetic properties of a wide range of drugs and diagnostic agents. A primary area in which improvement is needed for liposomal drug delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79271bc4b57a942a580c16fed9af3571
https://doi.org/10.1002/cbic.202200402
https://doi.org/10.1002/cbic.202200402
Publikováno v:
Bioorganic & Medicinal Chemistry. 87:117301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556e9232eb3d66429746a3680dadf1b5
https://doi.org/10.1016/j.bmc.2023.117301
https://doi.org/10.1016/j.bmc.2023.117301
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af77457c3f661d8da7b0ef36674374f4
https://doi.org/10.1002/chem.202202129
https://doi.org/10.1002/chem.202202129
Autor:
Jinchao Lou, Michael D. Best
Publikováno v:
Bioconjugate Chemistry. 31:2220-2230
Liposomes have proven to be effective nanocarriers due to their ability to encapsulate and deliver a wide variety of therapeutic cargo. A key goal of liposome research is to enhance control over content release at diseased sites. Though a number of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3163c6c3d2525e414b4a207fa8f675
https://doi.org/10.1021/acs.bioconjchem.0c00397
https://doi.org/10.1021/acs.bioconjchem.0c00397