Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Michael Aitchison"'
Autor:
Mariya Melnychuk, Cecilia Vindrola-Padros, Michael Aitchison, Caroline S. Clarke, Naomi J. Fulop, Claire Levermore, Satish B. Maddineni, Caroline M. Moore, Muntzer M. Mughal, Catherine Perry, Kathy Pritchard-Jones, Angus I. G. Ramsay, David Shackley, Jonathan Vickers, Stephen Morris
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The centralisation of specialist cancer surgical services across London Cancer and Greater Manchester Cancer, England, may significantly change how patients experience care. These centres are changing specialist surgical pathways
Externí odkaz:
https://doaj.org/article/562e4194a4fa49e3b770d60e3eaa903c
Cascade Fumarate Hydratase mutation screening allows early detection of kidney tumour: a case report
Autor:
Melanie M. Y. Chan, Angela Barnicoat, Faiz Mumtaz, Michael Aitchison, Lucy Side, Helen Brittain, Alan W. H. Bates, Daniel P. Gale
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Fumarate hydratase (FH) deficiency is a rare autosomal recessive disorder which results in a major defect in cellular metabolism. It presents in infancy with progressive encephalopathy, hypotonia, seizures and failure to thrive an
Externí odkaz:
https://doaj.org/article/843c7ead651f4cba854b3e3e20577ff8
Autor:
Naomi J. Fulop, Angus I. G. Ramsay, Cecilia Vindrola-Padros, Michael Aitchison, Ruth J. Boaden, Veronica Brinton, Caroline S. Clarke, John Hines, Rachael M. Hunter, Claire Levermore, Satish B. Maddineni, Mariya Melnychuk, Caroline M. Moore, Muntzer M. Mughal, Catherine Perry, Kathy Pritchard-Jones, David C. Shackley, Jonathan Vickers, Stephen Morris
Publikováno v:
Implementation Science, Vol 11, Iss 1, Pp 1-14 (2016)
Abstract Background There are longstanding recommendations to centralise specialist healthcare services, citing the potential to reduce variations in care and improve patient outcomes. Current activity to centralise specialist cancer surgical service
Externí odkaz:
https://doaj.org/article/927120f941a44519b2f86f97d4059f91
Autor:
Thomas Powles, David J. Harrison, Ian M. Overton, Michael Aitchison, Axel Bex, Daniel Berney, Antony C.P. Riddick, S. Alan McNeill, Peter Mullen, Marie O'Donnell, Jyoti Nanda, Alan Mackay, Alexander L.R. Lubbock, Lel Eory, Alexander Laird, Fiach C. O'Mahony, Grant D. Stewart
Purpose: The aim of this study was to investigate the effect of VEGF-targeted therapy (sunitinib) on molecular intratumoral heterogeneity (ITH) in metastatic clear cell renal cancer (mccRCC).Experimental Design: Multiple tumor samples (n = 187 sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738a2f7a83396a6b73601baba6b814bd
https://doi.org/10.1158/1078-0432.c.6523416
https://doi.org/10.1158/1078-0432.c.6523416
Autor:
Thomas Powles, David J. Harrison, Ian M. Overton, Michael Aitchison, Axel Bex, Daniel Berney, Antony C.P. Riddick, S. Alan McNeill, Peter Mullen, Marie O'Donnell, Jyoti Nanda, Alan Mackay, Alexander L.R. Lubbock, Lel Eory, Alexander Laird, Fiach C. O'Mahony, Grant D. Stewart
Supplementary Figures 1-2, Supplementary Tables 1-2. Fig. S1. Histogram showing lack of correlation between differential protein and RNA expression levels between sunitinib naive and treated patient samples; Figure S2: Dendrograms illustrating superv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129c6bfacb49741bef08bee8ccb39e15
https://doi.org/10.1158/1078-0432.22456785
https://doi.org/10.1158/1078-0432.22456785
Autor:
Joana B. Neves, Soha El-Sheikh, Umberto Capitanio, Filipe B. Rodrigues, Maxine G. B. Tran, Hannah Warren, Prasad Patki, Lee Alexander Grant, David Cullen, Stefano Agnesi, Axel Bex, Rebecca Varley, Michael Aitchison, Faiz Mumtaz, Ravi Barod, Yuigi Yuminaga, Nicola Rode, Miles Walkden, My-Anh Tran-Dang, John Withington
Publikováno v:
BJU International. 128:722-727
OBJECTIVES To study the natural history of renal oncocytomas and address indications for intervention by determining how growth is associated with renal function over time, the reasons for surgery and ablation, and disease-specific survival. PATIENTS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3692258db97368aef7adcf6628a809ed
https://doi.org/10.1111/bju.15499
https://doi.org/10.1111/bju.15499
Autor:
Naeem Soomro, Jan Lecouturier, Deborah D Stocken, Jing Shen, Ann Marie Hynes, Holly F Ainsworth, David Breen, Grenville Oades, David Rix, Michael Aitchison
Publikováno v:
Health Technology Assessment, Vol 21, Iss 81 (2017)
Background: There is uncertainty around the appropriate management of small renal tumours. Treatments include partial nephrectomy, ablation and active surveillance. Objectives: To explore the feasibility of a randomised trial of ablation versus activ
Externí odkaz:
https://doaj.org/article/92bfce2de63045f5aec39796617ac8ac
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd3fc85b7e4d0054cc1edab395c003e3
https://doi.org/10.1530/endoabs.77.p25
https://doi.org/10.1530/endoabs.77.p25
Autor:
Joana B. Neves, Maxine G. B. Tran, Thomas Powles, Michael Aitchison, Scott Shepherd, David Cullen
Publikováno v:
Journal of Clinical Urology. 12:314-319
Objectives: To report on the performance and cost of a surgeon-led renal cancer specialist multidisciplinary team meeting at a high-volume centre. Materials and methods: Retrospective analysis of 1500 consecutive cases discussed from 2 September 2015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30bf8d9cf21c1f2244279b7d136f8590
https://doi.org/10.1177/2051415819829309
https://doi.org/10.1177/2051415819829309
Autor:
Joana B. Neves, Faiz Mumtaz, John Withington, Maxine G. B. Tran, Prasad Patki, Axel Bex, Tim O'Brien, Michael Aitchison, Ravi Barod, Sarah Fowler
Publikováno v:
BJU International. 121:893-899
OBJECTIVES: To report on the contemporary UK experience of surgical management of renal oncocytomas. SUBJECTS AND METHODS: Descriptive analysis of practice and postoperative outcomes of cases with a final histological diagnosis of oncocytoma included
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8167c61a4ae925337d64ec8473a04ec
https://doi.org/10.1111/bju.14159
https://doi.org/10.1111/bju.14159