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Autor:
Mona Sydow-Bäckman, Anders Berkenstam, Göran Bertilsson, Patrik Blomquist, Rolf Ohlsson, Hans Postlind, Lena Jendeberg, Michael Åsman, Kristian Svensson, Jessica Heidrich
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12208-12213
Nuclear receptors regulate metabolic pathways in response to changes in the environment by appropriate alterations in gene expression of key metabolic enzymes. Here, a computational search approach based on iteratively built hidden Markov models of n