Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michael, Stepanavage"'
Autor:
Michael Davidson, Sherry Xueyu Liu, Philip Barter, Eliot A. Brinton, Christopher P. Cannon, Antonio M. Gotto, Jr., Elizabeth T. Leary, Sukrut Shah, Michael Stepanavage, Yale Mitchel, Hayes M. Dansky
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 2, Pp 467-472 (2013)
Estimation of low-density lipoprotein cholesterol (LDL-C) using the Friedewald (FR) formula is often inaccurate when triglycerides are elevated or VLDL particle composition is altered. We hypothesized that LDL-C estimation by the FR formula and other
Externí odkaz:
https://doaj.org/article/6a2fcbd9ba29424f83ed05a6e6cfc2d9
Autor:
Russell S. Scott, Henk D. Bakker, John J.P. Kastelein, Patrice Perron, Leiv Ose, Aditi Sapre, Michael Stepanavage, Tamas Szamosi, Marie Lambert, A S Paul van Trotsenburg, Saskia de Jongh, Mary B. Tuohy, Dries Dobbelaere, M. Saborio, Barry Gumbiner, Claude Gagné, Michele Mercuri
Publikováno v:
Circulation, 106(17), 2231-2237. Lippincott Williams and Wilkins
Background— A multicenter, randomized, double-blind, placebo-controlled study was conducted to evaluate LDL cholesterol–lowering efficacy, overall safety, and tolerability and the influence on growth and pubertal development of simvastatin in a l
Publikováno v:
Drug Information Journal. 35:1235-1246
The intervention of most clinical therapies typically involves shifting the central tendency of a response variable. There are many analytical methods to summarize these shifts and provide inferential results for treatment differences. Differences be
Autor:
J.J.P. Kastelein, Leiv Ose, William Insull, Santiago Campodonico, Michael Stepanavage, Russell S. Scott, Mei X. Wu, Helmut G. Schrott, Michael Melino, Michael H. Davidson, Yale B. Mitchel, Donald B. Hunninghake, Michele Mercuri, Ivan D. Escobar, Ann C. Tate, Evan A. Stein
Publikováno v:
Clinical Cardiology. 23:39-46
Background: Elevated levels of low-density lipoprotein (LDL) cholesterol promote the development of atherosclerosis and coronary heart disease. Hypothesis: Simvastatin 80 mg/day will be more effective than simvastatin 40 mg/day at reducing LDL choles
Autor:
Yale B. Mitchel, Evan A. Stein, Stuart R. Weiss, Helmut G. Schrott, Michael Stepanavage, Harold E. Bays, Carlos A. Dujovne, Michael Melino, Adrian S. Dobs, Michael H. Davidson
Publikováno v:
The American Journal of Cardiology. 82:311-316
This randomized, multicenter, double-blind parallel-group study was performed to evaluate the lipid-altering efficacy and safety of simvastatin 80 mg/day, a dose twice the current maximum recommended dose. At 20 centers in the United States, 521 male
Autor:
Timothy Mant, Timothy V Olah, Michael Stepanavage, Johanna Wittreich, Haiyung Cheng, Barry J. Gertz, Mark Edwards, David G. Sciberras, Polvino William J
Publikováno v:
British Journal of Clinical Pharmacology. 43:49-54
Aim We evaluated the pharmacokinetics and pharmacodynamics of oral MK-462 in comparison with oral sumatriptan in healthy male volunteers. Methods Sixteen healthy male volunteers were studied in a rising, single dose, alternating panel design with eig
Autor:
Kuang C. Yeh, Michael Stepanavage, Kristen Miller, Timothy J. Sullivan, Joyce D. King, Mary Scott, Kenneth Bachmann, Jules I. Schwartz, James H. Reese, Luis Jauregui
Publikováno v:
The Journal of Clinical Pharmacology. 35:529-535
The effects of famotidine (80 mg per day), cimetidine (1600 mg per day), and placebo on theophylline pharmacokinetic parameters in chronic obstructive pulmonary disease (COPD) patients were compared. This was an open-label, randomized, three-period c
Autor:
Christopher P, Cannon, Sukrut, Shah, Hayes M, Dansky, Michael, Davidson, Eliot A, Brinton, Antonio M, Gotto, Michael, Stepanavage, Sherry Xueyu, Liu, Patrice, Gibbons, Tanya B, Ashraf, Jennifer, Zafarino, Yale, Mitchel, Philip, Barter, T O, Wahl
Publikováno v:
The New England journal of medicine
Background Anacetrapib is a cholesteryl ester transfer protein inhibitor that raises high-density lipoprotein (HDL) cholesterol and reduces low-density lipoprotein (LDL) cholesterol. Methods We conducted a randomized, double-blind, placebo-controlled
Autor:
Eugene Braunwald, Yuliya Lokhnygina, Carolyn H. McCabe, Michael Stepanavage, Richard C. Pasternak, Christopher P. Cannon, Michael A. Blazing, Robert P. Giugliano, Thomas Musliner, Robert A. Harrington, Robert M. Califf
Publikováno v:
American heart journal. 159(5)
Autor:
Jonathan C. Cohen, Thomas Musliner, Manisha Chandalia, Helen H. Hobbs, Fang Xu, Susan G. Lakoski, Michael Stepanavage, Chun Lam, Scott M. Grundy, Gloria Lena Vega, Robert S. Lowe
Publikováno v:
The Journal of clinical endocrinology and metabolism. 95(2)
The level and duration of exposure to circulating low-density lipoprotein-cholesterol (LDL-C) are major contributors to coronary atherosclerosis. Therefore, optimal prevention will require long-term LDL-C reduction, making it important to select the