Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael, Stauske"'
Autor:
Wener Li, Michael Stauske, Xiaojing Luo, Stefan Wagner, Meike Vollrath, Carola S. Mehnert, Mario Schubert, Lukas Cyganek, Simin Chen, Sayed-Mohammad Hasheminasab, Gerald Wulf, Ali El-Armouche, Lars S. Maier, Gerd Hasenfuss, Kaomei Guan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Brugada syndrome (BrS) is one of the major causes of sudden cardiac death in young people, while the underlying mechanisms are not completely understood. Here, we investigated the pathophysiological phenotypes and mechanisms using induced pluripotent
Externí odkaz:
https://doaj.org/article/67390607ff314c6cac21aee37e21a20f
Autor:
Michael Stauske, Ignacio Rodriguez Polo, Wadim Haas, Debbra Yasemin Knorr, Thomas Borchert, Katrin Streckfuss-Bömeke, Ralf Dressel, Iris Bartels, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Rüdiger Behr
Publikováno v:
Cells, Vol 9, Iss 6, p 1349 (2020)
Non-human primates (NHP) are important surrogate models for late preclinical development of advanced therapy medicinal products (ATMPs), including induced pluripotent stem cell (iPSC)-based therapies, which are also under development for heart failur
Externí odkaz:
https://doaj.org/article/f1d71d0abb0041fc8ff434416b98ff68
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2454
Non-human primates (NHP), and in particular Old World monkeys including macaques and baboons, are key animal models for the late preclinical testing of novel stem cell-based therapies and other advanced therapy medical products (ATMP) for the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6eefb47fca75b739664ab8dd4f4ea1f
https://pubmed.ncbi.nlm.nih.gov/33772458
https://pubmed.ncbi.nlm.nih.gov/33772458
Autor:
Ignacio, Rodriguez-Polo, Michael, Stauske, Alexander, Becker, Iris, Bartels, Ralf, Dressel, Rüdiger, Behr
Publikováno v:
Primate Biology
Clinical application of regenerative therapies using embryonic or induced pluripotent stem cells is within reach. Progress made during recent years has encouraged researchers to address remaining open questions in order to finally translate experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b0d13cff54d506f69c34214aa6f8081
https://pubmed.ncbi.nlm.nih.gov/32110718
https://pubmed.ncbi.nlm.nih.gov/32110718
Autor:
Gabriela Salinas, Michael Stauske, Christof Lenz, Kaomei Guan, Karolina Sekeres, Gerd Hasenfuss, Lukas Cyganek, Wolfram-Hubertus Zimmermann, Malte Tiburcy, Sarah Henze, Kathleen Gerstenberg, Hanibal Bohnenberger
Publikováno v:
JCI Insight
Generation of homogeneous populations of subtype-specific cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) and their comprehensive phenotyping is crucial for a better understanding of the subtype-related disease mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba39658680f759e064256a2d922f58f
https://hdl.handle.net/21.11116/0000-0001-AB9A-121.11116/0000-0001-AB9E-D21.11116/0000-0001-AB9F-C21.11116/0000-0001-AB9C-F21.11116/0000-0001-AB9D-E
https://hdl.handle.net/21.11116/0000-0001-AB9A-121.11116/0000-0001-AB9E-D21.11116/0000-0001-AB9F-C21.11116/0000-0001-AB9C-F21.11116/0000-0001-AB9D-E
Autor:
Hanno L. Tan, Kaomei Guan, Arie O. Verkerk, Julien Barc, Michael Stauske, Arthur A.M. Wilde, Isabella Mengarelli, Christiaan C. Veerman, Connie R. Bezzina
Publikováno v:
Scientific reports, 6. Nature Publishing Group
Scientific Reports
Scientific Reports
Brugada syndrome (BrS) is a rare cardiac rhythm disorder associated with sudden cardiac death. Mutations in the sodium channel gene SCN5A are found in ~20% of cases while mutations in other genes collectively account for INa) in hiPSC-CMs from the 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54ced6e4194b54a3b36d3cbab9b7fe8
https://doi.org/10.1038/srep30967
https://doi.org/10.1038/srep30967
Publikováno v:
Regenerative Medicine-from Protocol to Patient ISBN: 9783319276083
Spermatogonial stem cells (SSCs) constitute one of the most important stem cell systems in the adult body. SSCs are unipotent and respond for spermatogenesis in the male as they can only differentiate into sperms within the testicular niche. The long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2445300d94372e0c663e999002a88dc8
https://doi.org/10.1007/978-3-319-27610-6_4
https://doi.org/10.1007/978-3-319-27610-6_4
Publikováno v:
Regenerative Medicine ISBN: 9789400756892
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3c1120de32262f0dd3748251a4adaa
https://doi.org/10.1007/978-94-007-5690-8_9
https://doi.org/10.1007/978-94-007-5690-8_9
Autor:
Malte Tiburcy, Jörg Jende, Michael Stauske, Stefan Wagner, Verena N. Lorenz, Katrin Streckfuss-Bömeke, Gerd Hasenfuss, Michael P. Schön, Kaomei Guan, Frieder Wolf, Wolfram H. Zimmermann, Simin Chen, Lars S. Maier, Ralf Dressel, Daniela Hübscher, Gerald Wulf, Azadeh Azizian
Publikováno v:
European heart journal. 34(33)
Aims Induced pluripotent stem cells (iPSCs) provide a unique opportunity for the generation of patient-specific cells for use in disease modelling, drug screening, and regenerative medicine. The aim of this study was to compare human-induced pluripot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8ceb445eddbbaff0284fe9516ade99
https://pubmed.ncbi.nlm.nih.gov/22798560
https://pubmed.ncbi.nlm.nih.gov/22798560
Autor:
K Streckfuss-Boemeke, Gerd Hasenfuss, C Fischer, C Oezcelic, Stefan Wagner, A Perret, Kaomei Guan, Lars S. Maier, Michael Stauske
Publikováno v:
Cardiovascular Research. 103:S48.2-S48
Purpose: The ability to generate patient-specific human induced pluripotent stem cells (ps-iPSCs) provides a unique opportunity for modeling heart disease. Dilated cardiomyopathy (DCM) is due to a progressive enlargement of the heart leading finally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed84fa70cceb27f04b7833403335f11
https://doi.org/10.1093/cvr/cvu083.2
https://doi.org/10.1093/cvr/cvu083.2