Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Michael, Spannagl"'
Autor:
Laura Vierbaum, Patricia Kaiser, Michael Spannagl, Folker Wenzel, Mario Thevis, Ingo Schellenberg
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/38b3563efc4444f1a1617234e8077bc5
Publikováno v:
Platelets, Vol 33, Iss 2, Pp 242-248 (2022)
The interaction of platelets with von Willebrand factor is essential for primary hemostasis. Concentration and activity of plasma von Willebrand factor are routine parameters in the assessment of hemostasis disorders. In addition to plasma von Willeb
Externí odkaz:
https://doaj.org/article/29facdf241504339808175682fe4c6ee
Autor:
Luise Goldmann, Rundan Duan, Thorsten Kragh, Georg Wittmann, Christian Weber, Reinhard Lorenz, Philipp von Hundelshausen, Michael Spannagl, Wolfgang Siess
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4021-4033 (2019)
Abstract: Activation of the platelet Fc-receptor CD32a (FcγRIIA) is an early and crucial step in the pathogenesis of heparin-induced thrombocytopenia type II (HIT) that has not been therapeutically targeted. Downstream FcγRIIA Bruton tyrosine kinas
Externí odkaz:
https://doaj.org/article/2d9e7772bfc94b21ac3710a27736c30e
Autor:
Rundan Duan, Luise Goldmann, Richard Brandl, Michael Spannagl, Christian Weber, Wolfgang Siess, Philipp von Hundelshausen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Bruton tyrosine kinase inhibitors (BTKi) are used in B-cell malignancies and in development against various autoimmune diseases. Since Btk is also involved in specific pathways of platelet activation, BTKi might be considered to target pl
Externí odkaz:
https://doaj.org/article/ac46e632b236415080f63ae9ae03dce7
Sensitive and specific assessment of recombinant von Willebrand factor in platelet function analyzer
Autor:
Isabell Pekrul, Thorsten Kragh, Peter L Turecek, Aaron R Novack, Helmut W Ott, Michael Spannagl
Publikováno v:
Platelets, Vol 30, Iss 2, Pp 264-270 (2019)
Background: Recombinant von Willebrand factor (rVWF), which was licensed in the United States in 2015, has the multimeric distribution of freshly secreted VWF with ultralarge (UL) and high molecular weight multimers (HMWM) from endothelial cells and
Externí odkaz:
https://doaj.org/article/c7f8ff570ae54d518594b16cc59322bc
Autor:
Manuela Thienel, Johannes B. Müller-Reif, Zhe Zhang, Vincent Ehreiser, Judith Huth, Khrystyna Shchurovska, Badr Kilani, Lisa Schweizer, Philipp E. Geyer, Maximilian Zwiebel, Julia Novotny, Enzo Lüsebrink, Gemma Little, Martin Orban, Leo Nicolai, Shaza El Nemr, Anna Titova, Michael Spannagl, Jonas Kindberg, Alina L. Evans, Orpheus Mach, Matthias Vogel, Steffen Tiedt, Steffen Ormanns, Barbara Kessler, Anne Dueck, Andrea Friebe, Peter Godsk Jørgensen, Monir Majzoub-Altweck, Andreas Blutke, Amin Polzin, Konstantin Stark, Stefan Kääb, Doris Maier, Jonathan M. Gibbins, Ulrich Limper, Ole Frobert, Matthias Mann, Steffen Massberg, Tobias Petzold
Publikováno v:
Science. 380:178-187
Venous thromboembolism (VTE) comprising deep venous thrombosis and pulmonary embolism is a major cause of morbidity and mortality. Short-term immobility-related conditions are a major risk factor for the development of VTE. Paradoxically, long-term i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d65d167f25b226e9011b21932fd2a20
https://doi.org/10.1126/science.abo5044
https://doi.org/10.1126/science.abo5044
Autor:
Tony, Badrick, Graham, Jones, W Greg, Miller, Mauro, Panteghini, Andrew, Quintenz, Sverre, Sandberg, Michael, Spannagl
Publikováno v:
Clinical Chemistry. 68:1238-1244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa1b4ff776d0dcb2435a2e07ba3f534
https://doi.org/10.1093/clinchem/hvac132
https://doi.org/10.1093/clinchem/hvac132
Publikováno v:
Medizinische Klinik, Intensivmedizin Und Notfallmedizin
Critically ill patients are at high risk of hemostasis disorders, which can be associated with both an increased risk of bleeding and an increased risk of thromboembolic events. In the case of acute vascular events, specific therapy with drug anticoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05df4170adf70c0281971452c24b21c0
https://doi.org/10.1007/s00063-021-00849-6
https://doi.org/10.1007/s00063-021-00849-6
Publikováno v:
Platelets. 33:242-248
The interaction of platelets with von Willebrand factor is essential for primary hemostasis. Concentration and activity of plasma von Willebrand factor are routine parameters in the assessment of hemostasis disorders. In addition to plasma von Willeb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0be9b1d8117d5e1b8da9c494dff2a4e
https://doi.org/10.1080/09537104.2020.1869715
https://doi.org/10.1080/09537104.2020.1869715
Autor:
Eva Base, Barbara Steinlechner, Beatrice Birkenberg, Martin Dworschak, Hendrik Jan Ankersmit, Petra Zeidler, Michael Spannagl, Bernd Jilma, Peter Quehenberger, Michael Hiesmayr
Publikováno v:
The Annals of Thoracic Surgery. 109:e233-e239
Background Patients with severe aortic valve stenosis have a markedly reduced platelet function as measured by a prolonged collagen adenosine diphosphate closure time (CADP-CT) determined by the platelet function analyzer PFA-100. We hypothesized tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95c359ae88919999b5cc63a8434da47d
https://doi.org/10.1016/j.athoracsur.2019.12.002
https://doi.org/10.1016/j.athoracsur.2019.12.002