Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael, Shires"'
Autor:
Jonathan Berrout, Eleni Kyriakopoulou, Lavanya Moparthi, Alexandra S. Hogea, Liza Berrout, Cristina Ivan, Mihaela Lorger, John Boyle, Chris Peers, Stephen Muench, Jacobo Elies Gomez, Xin Hu, Carolyn Hurst, Thomas Hall, Sujanitha Umamaheswaran, Laura Wesley, Mihai Gagea, Michael Shires, Iain Manfield, Margaret A. Knowles, Simon Davies, Klaus Suhling, Yurema Teijeiro Gonzalez, Neil Carragher, Kenneth Macleod, N. Joan Abbott, George A. Calin, Nikita Gamper, Peter M. Zygmunt, Zahra Timsah
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
TRPA1 has been reported to contribute lung cancer adenocarcinoma (LUAD), but the mechanisms are unclear. Here the authors propose that TRPA1/FGFR2 interaction is functional in LUAD and show that astrocytes oppose brain metastasis by mediating the dow
Externí odkaz:
https://doaj.org/article/33513ba93d3143cf9c9bd5f381eb5965
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Table S1: Baseline patient demographics and disease characteristics. Table S2: mRNA/IHC AREG/EREG concordance table. Figure S1: AREG/EREG IHC scatterplot. Table S3: Prognostic effect of dichotomous AREG/EREG. Table S4: AREG/EREG and RECIST response r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d26093065ca47cac56c3fafb14b7ba6
https://doi.org/10.1158/1078-0432.22478486.v1
https://doi.org/10.1158/1078-0432.22478486.v1
Autor:
Kandavel Shanmugam, Philip Quirke, Matthew T. Seymour, Isaac Bai, Michael Barnes, Jennifer H. Barrett, Nicholas P. West, Dongyao Yan, Wen-Wei Liu, Kien Nguyen, Xingwei Wang, Jim Martin, Zuo Zhao, Uday Kurkure, Auranuch Lorsakul, Christoph Guetter, Andrea Muranyi, Xiao-Meng Xu, Judith Pugh, Shalini Singh, Liping Zhang, Sarah Brown, Susan D. Richman, Michael Shires, Faye Elliott, Jenny F. Seligmann, Christopher J.M. Williams
Purpose:High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3918d1658590fe73e85875c77ed53656
https://doi.org/10.1158/1078-0432.c.6529961
https://doi.org/10.1158/1078-0432.c.6529961
Autor:
Michael Shires
Publikováno v:
Partnership: The Canadian Journal of Library and Information Practice and Research, Vol 12, Iss 2 (2018)
On March 22, 2017, the Government of Saskatchewan tabled its budget for fiscal year 2017-2018. There were deep cuts in many sectors. One of the biggest budget cuts percentage-wise was to public libraries. The Ministry of Education announced that 100%
Externí odkaz:
https://doaj.org/article/c32f1efa8187415ebd30926200398131
Autor:
Auranuch Lorsakul, Andrea Muranyi, Uday Kurkure, Kien Nguyen, Wen-Wei Liu, Isaac Bai, Jennifer H. Barrett, Christoph Guetter, Kandavel Shanmugam, Matthew T. Seymour, Philip Quirke, Michael Barnes, Dongyao Yan, Jenny F. Seligmann, Susan D. Richman, Zuo Zhao, Nicholas P. West, Xiao-Meng Xu, Xingwei Wang, Liping Zhang, James R. Martin, Faye Elliott, Michael Shires, Christopher J.M. Williams, Sarah Brown, Judith Pugh, Shalini Singh
Publikováno v:
Clinical Cancer Research. 27:3422-3431
Purpose: High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6101746c3c8a8ca70174ed4fdbc9e5e5
https://doi.org/10.1158/1078-0432.ccr-21-0120
https://doi.org/10.1158/1078-0432.ccr-21-0120
Autor:
Michael Shires
Publikováno v:
Partnership: The Canadian Journal of Library and Information Practice and Research, Vol 10, Iss 2 (2016)
Saskatchewan’s Multitype Library Board (MLB) celebrates its 20th anniversary in 2016. It was established under the passage of the provincial government’s The Libraries Co- operation Act in 1996 to facilitate the co-operative development of the mu
Externí odkaz:
https://doaj.org/article/37cbb3c7016b42aabf36330813925331
Autor:
Helen Sewell, Nick Hornigold, Naveen S. Vasudev, Eamonn R. Maher, Margaret A. Knowles, Mini Menon, Tsutomu Fukuwatari, Yasser Riazalhosseini, Alvis Brazma, Karen R. Dunn, Selina Bhattarai, Rachel A. Craven, Rosamonde E. Banks, Adrian L. Harris, Julie E. Burns, Alexandre Zougman, Peter Selby, Lara Feulner, Ghislaine Scelo, Michael Shires, Sebastian Trainor, Rebecca Shreeve, Joanne Brown, Mark Lathrop
Publikováno v:
British Journal of Cancer
Funder: EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf38d744f03fe1353bc8ab9676fde672
http://europepmc.org/articles/PMC7341846
http://europepmc.org/articles/PMC7341846
Autor:
Andrew Scarsbrook, John D Wright, Michael Shires, Charalampos Tsoumpas, Christopher Cawthorne, Marc A. Bailey, Lucinda J L Craggs, Stephen J. Archibald, Ping He, Joanna Koch-Paszkowski, Richa Gandhi, Juozas Domarkas
Publikováno v:
Journal of Nuclear Cardiology. 28:1961-1971
Background Abdominal aortic aneurysm (AAA) is a focal aortic dilatation progressing towards rupture. Non-invasive AAA-associated cell proliferation biomarkers are not yet established. We investigated the feasibility of the cell proliferation radiotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc88af6ebe3af069279dca908372c9d
https://doi.org/10.1007/s12350-019-01946-y
https://doi.org/10.1007/s12350-019-01946-y
Autor:
Christopher J M, Williams, Jenny F, Seligmann, Faye, Elliott, Michael, Shires, Susan D, Richman, Sarah, Brown, Liping, Zhang, Shalini, Singh, Judith, Pugh, Xiao-Meng, Xu, Andrea, Muranyi, Christoph, Guetter, Auranuch, Lorsakul, Uday, Kurkure, Zuo, Zhao, Jim, Martin, Xingwei, Wang, Kien, Nguyen, Wen-Wei, Liu, Dongyao, Yan, Nicholas P, West, Jennifer H, Barrett, Michael, Barnes, Isaac, Bai, Matthew T, Seymour, Philip, Quirke, Kandavel, Shanmugam
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(12)
High tumor mRNA levels of the EGFR ligands amphiregulin (AREG) and epiregulin (EREG) are associated with anti-EGFR agent response in metastatic colorectal cancer (mCRC). However, ligand RNA assays have not been adopted into routine practice due to is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcaec9959e1cdc2c93594b7dec3a6a81
https://pubmed.ncbi.nlm.nih.gov/33888518
https://pubmed.ncbi.nlm.nih.gov/33888518
Autor:
Eleni Kyriakopoulou, Liza Berrout, Margaret A. Knowles, Klaus Suhling, Carolyn D. Hurst, Peter M. Zygmunt, Michael Shires, Simon Davies, Sujanitha Umamaheswaran, Lavanya Moparthi, Nikita Gamper, Xin Hu, Stephen P. Muench, Thomas Hall, N. Joan Abbott, Mihai Gagea, Alexandra S. Hogea, Yurema Teijeiro Gonzalez, Mihaela Lorger, Chris Peers, Cristina-Elena Ivan, Kenneth G. MacLeod, Zahra Timsah, Laura Wesley, Jonathan Berrout, Jacobo Elies Gomez, Iain W. Manfield, Neil O. Carragher, John F. Boyle, George A. Calin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Berrout, J, Kyriakopoulou, E, Moparthi, L, S. Hogea, A, Berrout, L, Ivan, C, Lorger, M, Boyle, J, Peers, C, Muench, S, Elies Gomez, J, Hu, X, Hurst, C, Hall, T, Umamaheswaran, S, Wesley, L, Gagea, M, Shires, M, Manfield, I, A. Knowles, M, Davies, S, Suhling, K, Teijeiro Gonzalez, Y, Carragher, N, Macleod, K, Abbott, N J, A. Calin, G, Gamper, N, M. Zygmunt, P & Timsah, Z 2017, ' TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p ', Nature Communications . https://doi.org/10.1038/s41467-017-00983-w
Berrout, J, Kyriakopoulou, E, Moparthi, L, Hogea, A S, Berrout, L, Ivan, C, Lorger, M, Boyle, J, Peers, C, Muench, S, Gomez, J E, Hu, X, Hurst, C, Hall, T, Umamaheswaran, S, Wesley, L, Gagea, M, Shires, M, Manfield, I, Knowles, M A, Davies, S, Suhling, K, Gonzalez, Y T, Carragher, N, Macleod, K, Abbott, N J, Calin, G A, Gamper, N, Zygmunt, P M & Timsah, Z 2017, ' TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p ', Nature Communications, vol. 8, no. 1, 983, pp. 1-15 . https://doi.org/10.1038/s41467-017-00983-w
Nature Communications
Berrout, J, Kyriakopoulou, E, Moparthi, L, S. Hogea, A, Berrout, L, Ivan, C, Lorger, M, Boyle, J, Peers, C, Muench, S, Elies Gomez, J, Hu, X, Hurst, C, Hall, T, Umamaheswaran, S, Wesley, L, Gagea, M, Shires, M, Manfield, I, A. Knowles, M, Davies, S, Suhling, K, Teijeiro Gonzalez, Y, Carragher, N, Macleod, K, Abbott, N J, A. Calin, G, Gamper, N, M. Zygmunt, P & Timsah, Z 2017, ' TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p ', Nature Communications . https://doi.org/10.1038/s41467-017-00983-w
Berrout, J, Kyriakopoulou, E, Moparthi, L, Hogea, A S, Berrout, L, Ivan, C, Lorger, M, Boyle, J, Peers, C, Muench, S, Gomez, J E, Hu, X, Hurst, C, Hall, T, Umamaheswaran, S, Wesley, L, Gagea, M, Shires, M, Manfield, I, Knowles, M A, Davies, S, Suhling, K, Gonzalez, Y T, Carragher, N, Macleod, K, Abbott, N J, Calin, G A, Gamper, N, Zygmunt, P M & Timsah, Z 2017, ' TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p ', Nature Communications, vol. 8, no. 1, 983, pp. 1-15 . https://doi.org/10.1038/s41467-017-00983-w
Recent evidence suggests that the ion channel TRPA1 is implicated in lung adenocarcinoma (LUAD), where its role and mechanism of action remain unknown. We have previously established that the membrane receptor FGFR2 drives LUAD progression through ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464a839bb442843b4d981ad626e44d93
http://link.springer.com/article/10.1038/s41467-017-00983-w
http://link.springer.com/article/10.1038/s41467-017-00983-w