Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Michael, Schumm"'
Autor:
Amadeus T Heinz, Friso G.J. Calkoen, Alexander Derbich, Lea Miltner, Christian Seitz, Michaela Doering, Christiane Braun, Daniel Atar, Michael Schumm, Florian Heubach, Anne-Marie Arendt, Ansgar Schulz, Friedhelm R Schuster, Roland Meisel, Brigitte Strahm, Juergen Finke, Beatrice Heineking, Susanne Stetter, Gerda Silling, Daniel Stachel, Bernd Gruhn, Klaus-Michael Debatin, Juergen Foell, Johannes H Schulte, Wilhelm Woessmann, Christine Mauz-Körholz, Johanna Tischer, Tobias Feuchtinger, Rupert Handgretinger, Peter Lang
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Therapy-resistant viral reactivations contribute significantly to mortality after hematopoietic stem cell transplantation. Adoptive cellular therapy with virus-specific T cells (VST) has shown efficacy in various single-center trials. However, the sc
Externí odkaz:
https://doaj.org/article/6ada467cb16540358957b223184585b6
Autor:
Simona Jahnke, Hannes Schmid, Kathy-Ann Secker, Jakob Einhaus, Silke Duerr-Stoerzer, Hildegard Keppeler, Irmtraud Schober-Melms, Rebecca Baur, Michael Schumm, Rupert Handgretinger, Wolfgang Bethge, Lothar Kanz, Corina Schneidawind, Dominik Schneidawind
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative treatment option for hematologic malignancies but relapse remains the most common cause of death. Infusion of donor lymphocytes (DLIs) can induce remission and prolong survival by
Externí odkaz:
https://doaj.org/article/408572c894f945a9803769e6512d431b
Autor:
Steffen Hartleif, Michael Schumm, Michaela Döring, Markus Mezger, Peter Lang, Marc H. Dahlke, Joachim Riethmüller, Alfred Königsrainer, Rupert Handgretinger, Silvio Nadalin, Ekkehard Sturm
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Background. Calcineurin inhibitors (CNI) have significantly improved patient and graft survival in pediatric liver transplantation (pLT). However, CNI toxicity leads to significant morbidity. Moreover, CNIs cannot prevent long-term allograft injury.
Externí odkaz:
https://doaj.org/article/3eea493d05e34cd8a7f3476f40956ff0
Autor:
Claudia Treuner, Paul-Gerhardt Schlegel, Annika Erbacher, Michaela Döring, Christoph Faul, Katrin Lenglinger, Martin Vaegler, Michael Schumm, Johann Greil, Friederike Gieseke, Claudia Bettoni da Cunha Riehm, Peter Lang, Markus Mezger, Ingo Müller, Rupert Handgretinger, Karin Melanie Cabanillas Stanchi
Publikováno v:
Stem Cells and Development. 30:234-246
Steroid-refractory graft-versus-host disease (GvHD) is a life-threatening complication after allogeneic hematopoietic stem cell transplantation (alloHSCT). Alternative treatment options are often insufficient. Several studies have proven the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd429ed84ab9de4d1d57b198da14293c
https://doi.org/10.1089/scd.2020.0191
https://doi.org/10.1089/scd.2020.0191
Autor:
Karin Melanie Cabanillas Stanchi, Markus Mezger, Michael Schumm, Ingo Müller, Michaela Döring, Torsten Kluba, Ilias Tsiflikas, Peter Lang, Rupert Handgretinger, Peter Kahle, Annika Erbacher, Claudia Treuner, Katrin Lenglinger, Martin Vaegler
Publikováno v:
Stem Cells and Development. 29:811-822
Avascular necrosis (AVN) is a severe complication of immunosuppressant therapy or chemotherapy. A beneficial AVN therapy with core decompression (CD) and intraosseous infusion of mesenchymal stromal cells (MSCs) has been described in adult patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc70db7a0068031e85f0f1fbdda74f5
https://doi.org/10.1089/scd.2020.0019
https://doi.org/10.1089/scd.2020.0019
Autor:
Karin Melanie Cabanillas Stanchi, Judith Böhringer, Manuel Strölin, Samuel Groeschel, Katrin Lenglinger, Claudia Treuner, Christiane Kehrer, Lucia Laugwitz, Andrea Bevot, Nadja Kaiser, Michael Schumm, Peter Lang, Rupert Handgretinger, Ingeborg Krägeloh-Mann, Ingo Müller, Michaela Döring
Publikováno v:
Stem cells and development. 31(7-8)
Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder primarily affecting the white matter of the nervous system that results from a deficiency of the arylsulfatase A (ARSA). Mesenchymal stem cells (MSCs) are able to secrete ARSA and hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be9ce744a25017dbfbf7d7a77105d51
https://pubmed.ncbi.nlm.nih.gov/35323019
https://pubmed.ncbi.nlm.nih.gov/35323019
Autor:
Wolfgang A. Bethge, Matthias Eyrich, Stephan Mielke, Roland Meisel, Dietger Niederwieser, Paul G. Schlegel, Ansgar Schulz, Johann Greil, Donald Bunjes, Arne Brecht, Jurgen Kuball, Michael Schumm, Vladan Vucinic, Markus Wiesneth, Halvard Bonig, Kasper Westinga, Stefanie Biedermann, Silke Holtkamp, Sandra Karitzky, Michaela Malchow, Christiane Siewert, Rupert Handgretinger, Peter Lang
Publikováno v:
Bone Marrow Transplantation
Hematopoietic stem cell transplantation (HSCT) from haploidentical donors is a viable option for patients lacking HLA-matched donors. Here we report the results of a prospective multicenter phase I/II trial of transplantation of TCRαβ and CD19-depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d15987cc42b231ca9a41cc88cf8bd20
https://pubmed.ncbi.nlm.nih.gov/34952929
https://pubmed.ncbi.nlm.nih.gov/34952929
Autor:
Simona Jahnke, Irmtraud Schober-Melms, Wolfgang Bethge, Dominik Schneidawind, Rupert Handgretinger, Christoph Faul, Michael Schumm, Lothar Kanz, Corina Schneidawind
Publikováno v:
British Journal of Haematology. 186:60-71
Donor lymphocyte infusion (DLI) is an effective method to establish full donor chimerism or to prevent and treat relapse after allogeneic haematopoietic cell transplantation (allo-HCT). Usually, DLIs are collected from naive donors as steady-state ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef45c1c1a266725fd46bbb1115b65f6b
https://doi.org/10.1111/bjh.15881
https://doi.org/10.1111/bjh.15881
Autor:
Birgit Federmann, Martin Bornhauser, Christoph Meisner, Lambros Kordelas, Dietrich W. Beelen, Gernot Stuhler, Matthias Stelljes, Rainer Schwerdtfeger, Maximilian Christopeit, Gerhard Behre, Christoph Faul, Wichard Vogel, Michael Schumm, Rupert Handgretinger, Lothar Kanz, Wolfgang A. Bethge
Publikováno v:
Haematologica, Vol 97, Iss 10 (2012)
Background We report a prospective multicenter phase II study of haploidentical hematopoietic stem cell transplantation using CD3/CD19-depleted grafts after reduced intensity conditioning with fludarabine, thiotepa, melphalan and OKT-3.Design and Met
Externí odkaz:
https://doaj.org/article/2f84643d901a4eb59eebfe441c872aed
Autor:
Olga Kyrillopoulou, Ortwin Adams, Florian Babor, Britta Maecker-Kolhoff, Matthias Aubin, Roland Meisel, Friedhelm R. Schuster, Michael Schumm, Hiba Fouz, Katharina L. Gössling, Arndt Borkhardt, Peter Lang, Meinolf Siepermann, Britta Eiz-Vesper
Publikováno v:
Clinical Infectious Diseases. 68:1406-1409
Here, we report the case of severe adenoviremia in a 7-year-old boy with highly-resistant, acute leukemia. A combined approach of αβTCR-CD19-depleted stem cell transplantation, enabling immunosuppression-free post-transplant care, and early transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85703b3604b9b2c287352989f5541b95
https://doi.org/10.1093/cid/ciy820
https://doi.org/10.1093/cid/ciy820