Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Michael, Schöll"'
Autor:
Lisa Quenon, Lyduine E. Collij, David Vállez Garcia, Isadora Lopes Alves, Thomas Gérard, Vincent Malotaux, Lara Huyghe, Juan Domingo Gispert, Frank Jessen, Pieter Jelle Visser, Anouk den Braber, Craig W. Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S. Luckett, Michael Schöll, Giovanni B. Frisoni, Christopher Buckley, Andrew Stephens, Daniele Altomare, Lisa Ford, Cindy Birck, Anja Mett, Rossella Gismondi, Robin Wolz, Sylke Grootoonk, Richard Manber, Mahnaz Shekari, Renaud Lhommel, Laurence Dricot, Adrian Ivanoiu, Gill Farrar, Frederik Barkhof, Bernard J. Hanseeuw, the AMYPAD Consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associated with cognitive decline in clinically normal (CN) individuals. However, it is less well established whether there is an a
Externí odkaz:
https://doaj.org/article/916789749e284220b7135dd30f36111c
Autor:
Nicolai Franzmeier, Amir Dehsarvi, Anna Steward, Davina Biel, Anna Dewenter, Sebastian Niclas Roemer, Fabian Wagner, Mattes Groß, Matthias Brendel, Alexis Moscoso, Prithvi Arunachalam, Kaj Blennow, Henrik Zetterberg, Michael Ewers, Michael Schöll
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract In Alzheimer’s disease, amyloid-beta (Aβ) triggers the trans-synaptic spread of tau pathology, and aberrant synaptic activity has been shown to promote tau spreading. Aβ induces aberrant synaptic activity, manifesting in increases in the
Externí odkaz:
https://doaj.org/article/805dd9e85c8145c99b2ccade83ebcf4a
Autor:
Alejandro Costoya-Sánchez, Alexis Moscoso, Tomás Sobrino, Álvaro Ruibal, Michel J. Grothe, Michael Schöll, Jesús Silva-Rodríguez, Pablo Aguiar
Publikováno v:
NeuroImage, Vol 289, Iss , Pp 120537- (2024)
Background: [18F]flortaucipir (FTP) tau PET quantification is known to be affected by non-specific binding in off-target regions. Although partial volume correction (PVC) techniques partially account for this effect, their inclusion may also introduc
Externí odkaz:
https://doaj.org/article/3923e1377b104ed499e48edcd7d55c57
Autor:
Ilse Bader, Ilona Bader, Isadora Lopes Alves, David Vállez García, Bruno Vellas, Bruno Dubois, Mercè Boada, Marta Marquié, Daniele Altomare, Philip Scheltens, Rik Vandenberghe, Bernard Hanseeuw, Michael Schöll, Giovanni B. Frisoni, Frank Jessen, Agneta Nordberg, Miia Kivipelto, Craig W. Ritchie, Oriol Grau-Rivera, José Luis Molinuevo, Lisa Ford, Andrew Stephens, Rossella Gismondi, Juan Domingo Gispert, Gill Farrar, Frederik Barkhof, Pieter Jelle Visser, Lyduine E. Collij, on behalf of the AMYPAD consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The mismatch between the limited availability versus the high demand of participants who are in the pre-dementia phase of Alzheimer’s disease (AD) is a bottleneck for clinical studies in AD. Nevertheless, potential enrollment ba
Externí odkaz:
https://doaj.org/article/53ca117657b04d869c1e2fc37d173899
Autor:
Antoinette O’Connor, David M. Cash, Teresa Poole, Pawel J. Markiewicz, Maggie R. Fraser, Ian B. Malone, Jieqing Jiao, Philip S. J. Weston, Shaney Flores, Russ Hornbeck, Eric McDade, Michael Schöll, Brian A. Gordon, Randall J. Bateman, Tammie L. S. Benzinger, Nick C. Fox
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Cortical tau accumulation is a key pathological event that partly defines Alzheimer’s disease (AD) onset and is associated with cognitive decline and future disease progression. However, an improved understanding of the timing and pattern
Externí odkaz:
https://doaj.org/article/555f699f8f0e43d889b6f8d82c8b8ed1
Autor:
Anniina Snellman, Laura L. Ekblad, Jouni Tuisku, Mikko Koivumäki, Nicholas J. Ashton, Juan Lantero-Rodriguez, Thomas K. Karikari, Semi Helin, Marco Bucci, Eliisa Löyttyniemi, Riitta Parkkola, Mira Karrasch, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Juha O. Rinne
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Neuroinflammation, characterized by increased reactivity of microglia and astrocytes in the brain, is known to be present at various stages of the Alzheimer’s disease (AD) continuum. However, its presence and relationship with a
Externí odkaz:
https://doaj.org/article/c691f60e95844b5ab184a43042c094dc
Autor:
Peter Young, Lieuwe Appel, Andreas Tolf, Savvas Kosmidis, Joachim Burman, Anna Rieckmann, Michael Schöll, Mark Lubberink
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract Background Quantitative positron emission tomography (PET) scans of the brain typically require arterial blood sampling but this is complicated and logistically challenging. One solution to remove the need for arterial blood sampling is the
Externí odkaz:
https://doaj.org/article/5b2a28209ff94e4a8d539cbc01a0237f
Autor:
Davina Biel, Ying Luan, Matthias Brendel, Paul Hager, Anna Dewenter, Alexis Moscoso, Diana Otero Svaldi, Ixavier A. Higgins, Michael Pontecorvo, Sebastian Römer, Anna Steward, Anna Rubinski, Lukai Zheng, Michael Schöll, Sergey Shcherbinin, Michael Ewers, Nicolai Franzmeier, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Tau-PET is a prognostic marker for cognitive decline in Alzheimer’s disease, and the heterogeneity of tau-PET patterns matches cognitive symptom heterogeneity. Thus, tau-PET may allow precision-medicine prediction of individual
Externí odkaz:
https://doaj.org/article/ccfa8ae4ae3c45568c2230133b4c334b
Autor:
William Coath, Marc Modat, M. Jorge Cardoso, Pawel J. Markiewicz, Christopher A. Lane, Thomas D. Parker, Ashvini Keshavan, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Ninon Burgos, John Dickson, Anna Barnes, David L. Thomas, Daniel Beasley, Ian B. Malone, Andrew Wong, Kjell Erlandsson, Benjamin A. Thomas, Michael Schöll, Sebastien Ourselin, Marcus Richards, Nick C. Fox, Jonathan M. Schott, David M. Cash, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract INTRODUCTION The Centiloid scale aims to harmonize amyloid beta (Aβ) positron emission tomography (PET) measures across different analysis methods. As Centiloids were created using PET/computerized tomography (CT) data and are influenced by
Externí odkaz:
https://doaj.org/article/89fc878da77c45b0abc21824ecd8a625
Autor:
Alexis Moscoso, Melissa C. Wren, Tammaryn Lashley, Erik Arstad, Melissa E. Murray, Nick C. Fox, Kerstin Sander, Michael Schöll
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/483bdb8b9982482da2936b48f6819fa4