Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michael, Sandino"'
Publikováno v:
The Discovery and Utility of Chemical Probes in Target Discovery ISBN: 9781788015899
Although traditional methods for drug discovery follow a protein-centric view, emerging studies on the importance of RNA have shed light on the need for a new category of therapeutics: RNA-targeted molecules. Their dysregulation has been associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37da3833f26e990d664310b10cb205dd
https://doi.org/10.1039/9781839160745-00214
https://doi.org/10.1039/9781839160745-00214
Autor:
Taoda Shi, Lynn Kaneko, Ryan Busse, Eli Chapman, Mae Zhang, Jason M. Machulis, Donna D. Zhang, Damian J. Mason, Michael Sandino, Andrew J. Ambrose
Publikováno v:
ACS Sustainable Chemistry & Engineering. 7:1524-1528
Thieno[2,3-d]pyrimidin-4(3H)-ones are important pharmacophores that have previously required a three-step synthesis with two chromatography steps. We herein report a green approach to the synthesis...
Autor:
Taoda, Shi, Lynn, Kaneko, Michael, Sandino, Ryan, Busse, Mae, Zhang, Damian, Mason, Jason, Machulis, Andrew J, Ambrose, Donna D, Zhang, Eli, Chapman
Publikováno v:
ACS sustainable chemistryengineering. 7(1)
Thieno[2,3-d]pyrimidin-4(3H)-ones are important pharmacophores that previously required a three step synthesis with two chromatography steps. We herein report a green approach to the synthesis of this pharmacologically important class of compounds vi