Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Michael, Reth"'
Autor:
Andreas Hildenbrand, Precious Cramer, Milena Bertolotti, Nathalie Sophia Kaiser, Kathrin Kläsener, Clara Muriel Nickel, Michael Reth, Albert Heim, Hartmut Hengel, Hans-Gerhard Burgert, Zsolt Ruzsics
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe early transcription unit 3 (E3) of human adenoviruses (HAdVs) encodes several immunoevasins, including the E3/49K protein, which is unique for species D of HAdVs. It is expressed as surface transmembrane protein and shed. E3/49K of HA
Externí odkaz:
https://doaj.org/article/7a5ba3131ec940d5b423370471844f5a
Autor:
Kathrin Kläsener, Nadja Herrmann, Liliana Håversen, Timothy Sundell, Martina Sundqvist, Christina Lundqvist, Paul T Manna, Charlotte A Jonsson, Marcella Visentini, Diana Ljung Sass, Sarah McGrath, Kristoffer Grimstad, Alaitz Aranburu, Karin Mellgren, Linda Fogelstrand, Huamei Forsman, Olov Ekwall, Jan Borén, Inger Gjertsson, Michael Reth, Inga‐Lill Mårtensson, Alessandro Camponeschi
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 10, Pp n/a-n/a (2024)
Abstract Objectives Paediatric Burkitt's lymphoma (pBL) is the most common childhood non‐Hodgkin B‐cell lymphoma. Despite the encouraging survival rates for most children, treating cases with relapse/resistance to current therapies remains challe
Externí odkaz:
https://doaj.org/article/5334ae4bfcbe40568cef6f2f3b2b82a5
Autor:
Michael Reth
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The recently determined cryo-EM structures of the T cell antigen receptor (TCR) and B cell antigen receptor (BCR) show in molecular details the interactions of the ligand-binding part with the signaling subunits but they do not reveal the signaling m
Externí odkaz:
https://doaj.org/article/fbaff73947fc426e97a72a566b831b53
Autor:
Niklas Vesper, Yaneth Ortiz, Frauke Bartels-Burgahn, Jianying Yang, Kathrin de la Rosa, Matthias Tenbusch, Sebastian Schulz, Stephanie Finzel, Hans-Martin Jäck, Hermann Eibel, Reinhard E. Voll, Michael Reth
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The SARS-CoV-2 pandemic has spread to all parts of the world and can cause life-threatening pneumonia and other severe disease manifestations known as COVID-19. This health crisis has resulted in a significant effort to stop the spread of this new co
Externí odkaz:
https://doaj.org/article/8028980ae84e44d8981c50d0be50140f
Autor:
Shuangshuang Zheng, Melanie Sieder, Michael Mitterer, Michael Reth, Marco Cavallari, Jianying Yang
Publikováno v:
PLoS Biology, Vol 17, Iss 12, p e3000569 (2019)
Membrane proteins are organized in nanoscale compartments. Their reorganization plays a crucial role in receptor activation and cell signaling. To monitor the organization and reorganization of membrane proteins, we developed a new branched proximity
Externí odkaz:
https://doaj.org/article/49064e6835c14bf2a5488af8cb6d9d17
Autor:
Ying Dong, Xiong Pi, Frauke Bartels-Burgahn, Deniz Saltukoglu, Zhuoyi Liang, Jianying Yang, Frederick W. Alt, Michael Reth, Hao Wu
Publikováno v:
Nature. 612:156-161
The B cell antigen receptor (BCR) is composed of a membrane-bound class M, D, G, E or A immunoglobulin for antigen recognition
TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections
Publikováno v:
eLife, Vol 8 (2019)
In mice, neonatally-developing, self-reactive B-1 cells generate steady levels of natural antibodies throughout life. B-1 cells can, however, also rapidly respond to infections with increased local antibody production. The mechanisms regulating these
Externí odkaz:
https://doaj.org/article/f40d19057a7b4f5183be06adfe9ac27a
Autor:
Marcin Łyszkiewicz, Daniel Kotlarz, Natalia Ziȩtara, Gudrun Brandes, Jana Diestelhorst, Silke Glage, Elias Hobeika, Michael Reth, Lukas A. Huber, Andreas Krueger, Christoph Klein
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
B-cell development and function depend on stage-specific signaling through the B-cell antigen receptor (BCR). Signaling and intracellular trafficking of the BCR are connected, but the molecular mechanisms of this link are incompletely understood. Her
Externí odkaz:
https://doaj.org/article/9323e58098774607b8426c3f25a2332c
Autor:
Hans-Georg Rammensee, Cécile Gouttefangeas, Sonja Heidu, Reinhild Klein, Beate Preuß, Juliane Sarah Walz, Annika Nelde, Sebastian P. Haen, Michael Reth, Jianying Yang, Ghazaleh Tabatabai, Hans Bösmüller, Helen Hoffmann, Michael Schindler, Oliver Planz, Karl-Heinz Wiesmüller, Markus W. Löffler
Publikováno v:
Vaccines, Vol 9, Iss 5, p 428 (2021)
We describe the results of two vaccinations of a self-experimenting healthy volunteer with SARS-CoV-2-derived peptides performed in March and April 2020, respectively. The first set of peptides contained eight peptides predicted to bind to the indivi
Externí odkaz:
https://doaj.org/article/1fb9244aa47644348c0c213da3a5c238
Autor:
Deniz Saltukoglu, Bugra Özdemir, Michael Holtmannspötter, Ralf Reski, Jacob Piehler, Rainer Kurre, Michael Reth
Publikováno v:
The EMBO journalReferences.
B lymphocytes recognize bacterial or viral antigens via different classes of the B cell antigen receptor (BCR). Protrusive structures termed microvilli cover lymphocyte surfaces, and are thought to perform sensory functions in screening antigen-beari