Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Michael, Polydefkis"'
Autor:
Michael Lane, Michael Polydefkis
Publikováno v:
Neurology and Therapy, Vol 13, Iss 6, Pp 1527-1533 (2024)
Abstract This article has been co-authored by a patient living with hereditary transthyretin (ATTRv) amyloidosis and a neurologist. This rare, progressive disease is associated with impairment of multiple organ systems, including the nerves, heart, a
Externí odkaz:
https://doaj.org/article/fd77ea5ca8b545ef87741b5935dc97a4
Autor:
Samira Anderson, Guido Cavaletti, Linda J. Hood, Michael Polydefkis, David N. Herrmann, Gary Rance, Brett King, Amy J. McMichael, Maryanne M. Senna, Brian S. Kim, Lynne Napatalung, Robert Wolk, Samuel H. Zwillich, Gregor Schaefer, Yankun Gong, Melanie Sisson, Holly B. Posner
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Reversible axonal swelling and brainstem auditory evoked potential (BAEP) changes were observed in standard chronic (9‐month) toxicology studies in dogs treated with ritlecitinib, an oral Janus kinase 3/tyrosine kinase expressed in hepatoc
Externí odkaz:
https://doaj.org/article/3530c0e1c1d5497d97bb7fe1b83e42ad
Autor:
Nerea Mora-Ayestaran, MD, Angela Dispenzieri, MD, Arnt V. Kristen, MD, Mathew S. Maurer, MD, Igor Diemberger, MD, Brian M. Drachman, MD, Martha Grogan, MD, Pritam Gupta, PhD, Oliver Glass, PhD, Leslie Amass, PhD, Pablo Garcia-Pavia, MD, PhD, Michele Emdin, Mazen Hanna, Olga Azevedo, Calogero Lino Cirami, Jose Gonzalez Costello, David Slosky, Henning Moelgaard, Jose Nativi Nicolau, Scott Hummel, Eun-Seok Jeon, Nowell Fine, Srinivas Murali, Edward Miller, Sanjiv Shah, Ronald Witteles, Marcia Waddington-Cruz, Daniel Lenihan, Yoshiki Sekijima, Johan Van Cleemput, Edileide de Barros Correia, Eve Cariou, Dianna Quan, Miriam Freimer, David Steidley, Anna Hüsing-Kabar, Violaine Plante-Bordeneuve, Hans Nienhuis, Jonas Wixner, Jeffrey Ralph, Hector Ventura, Sasa Zivkovic, Diego Delgado, Roberto Fernandéz Torrón, Stephen Gottlieb, William Cotts, Jose Tallaj, Robert Brunkhorst, Michael Polydefkis, Christopher Mueller, Carsten Tschoepe, Juan Gonzalez Moreno, Nitasha Sarswat, Jin Luo, James Tauras, Alberta Warner
Publikováno v:
JACC: Advances, Vol 3, Iss 8, Pp 101086- (2024)
Background: Wild-type transthyretin amyloidosis (ATTRwt amyloidosis) is primarily diagnosed in elderly men but diagnoses in younger patients and women have recently increased. Objectives: The purpose of this study was to examine age- and sex-related
Externí odkaz:
https://doaj.org/article/dc542adf430b4e7fb29d0bce4d17c600
Autor:
Abhishek Gami, MD, John Woller, MD, Paul Scheel, MD, Syed Abbas Ali, MBBS, Carol Ann Huff, MD, Charles Steenbergen, Jr., MD, PhD, Marc Halushka, MD, PhD, Kavita Sharma, MD, Michael Polydefkis, MD, Joban Vaishnav, MD
Publikováno v:
JACC: Case Reports, Vol 29, Iss 7, Pp 102285- (2024)
Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur. We present three cases of coexisting AL and ATTR cardiac amyloidosis and demonstrate th
Externí odkaz:
https://doaj.org/article/85300b1c20cb4439a2a4ed56f26fc6c3
Autor:
David Adams, Vincent Algalarrondo, Michael Polydefkis, Nitasha Sarswat, Michel S. Slama, Jose Nativi-Nicolau
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-17 (2021)
Abstract Background Hereditary transthyretin-mediated amyloidosis, also known as ATTRv amyloidosis (v for variant), is a rare, autosomal dominant, fatal disease, in which systemic amyloid progressively impairs multiple organs, leading to disability a
Externí odkaz:
https://doaj.org/article/bb662c9812aa4769aea875c173ecb963
Autor:
Ying Liu, Yuan Sun, Osefame Ewaleifoh, Josh Wei, Ruifa Mi, Jing Zhu, Ahmet Hoke, Michael Polydefkis
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Ethoxyquin (EQ), a quinolone-based antioxidant, has demonstrated neuroprotective properties against several neurotoxic drugs in a phenotypic screening and is shown to protect axons in animal models of chemotherapy-induced peripheral neuropat
Externí odkaz:
https://doaj.org/article/5c0248390807438bb3db8f0022d81282
Autor:
Teresa Coelho, David Adams, Isabel Conceição, Márcia Waddington-Cruz, Hartmut H. Schmidt, Juan Buades, Josep Campistol, John L. Berk, Michael Polydefkis, Jing Jing Wang, Jihong Chen, Marianne T. Sweetser, Jared Gollob, Ole B. Suhr
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Patisiran, an RNA interference therapeutic, has demonstrated robust reduction of wild-type and mutant transthyretin protein and was able to improve polyneuropathy and quality of life following 18 months of treatment in patients wi
Externí odkaz:
https://doaj.org/article/043b3f0175b643a0af6f21c8079884d9
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 10, Pp 2088-2096 (2019)
Abstract Objective To assess the effect of diabetes type on the long‐term rate and extent of epidermal nerve regeneration. Methods Subjects with well controlled type 1 diabetes mellitus (n = 11) or type 2 diabetes mellitus (n = 36), with normal ner
Externí odkaz:
https://doaj.org/article/e4945af65067454d9e7bfb39728f550f
Autor:
Serena Zampino, Farooq H. Sheikh, Joban Vaishnav, Daniel Judge, Baohan Pan, Amrita Daniel, Emily Brown, Gigi Ebenezer, Michael Polydefkis
Publikováno v:
Neurology. 100:e2036-e2044
Background and ObjectivesHereditary transthyretin amyloidosis (hATTR) is a rare autosomal dominant systemic disease with variable penetrance and heterogeneous clinical presentation. Several effective treatments can reduce mortality and disability, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87bef72ad4fca5527bc29980cf412b49
https://doi.org/10.1212/wnl.0000000000207158
https://doi.org/10.1212/wnl.0000000000207158
Autor:
Michael Polydefkis, Emre Aldinc, Hans Nienhuis, Chafic Karam, Senda Ajroud-Driss, Yoshiki Sekijima, Marcia Waddington-Cruz, Jennifer Barnes, Paul Nioi, Simina Ticau
Publikováno v:
Monday, April 24.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b538ac0621102830cdb2ab7328607d0
https://doi.org/10.1212/wnl.0000000000202198
https://doi.org/10.1212/wnl.0000000000202198