Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Michael, Pohl"'
Autor:
Timm M. Reissig, Swetlana Ladigan‐Badura, Anja Steinberg, Abdelouahid Maghnouj, Ting Li, Berlinda Verdoodt, Sven T. Liffers, Michael Pohl, Heiner Wolters, Christian Teschendorf, Richard Viebahn, Jakob Admard, Nicolas Casadei, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn, Deepak B. Vangala
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2396-2414 (2023)
Although approximately half of all metastatic colorectal cancers (mCRCs) harbour mutations in KRAS or NRAS, hardly any progress has been made regarding targeted treatment for this group over the last few years. Here, we investigated the efficacy of v
Externí odkaz:
https://doaj.org/article/43b89c56d838488bb188749e4ab6758c
Publikováno v:
Metals, Vol 14, Iss 5, p 588 (2024)
Hydrogen embrittlement (HE) poses the risk of premature failure for many metals, especially high-strength steels. Due to the utilization of hydrogen as an environmentally friendly energy source, efforts are made to improve the resistance to HE at ele
Externí odkaz:
https://doaj.org/article/4fd8d19e0bae4826b04b4f21a30da936
Liquid biopsy based HER2 amplification status in gastric cancer patients indicates clinical response
Autor:
Susanne Klein-Scory, Swetlana Ladigan-Badura, Thomas Mika, Berlinda Verdoodt, Andrea Tannapfel, Michael Pohl, Roland Schroers, Alexander Baraniskin
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21339- (2023)
Gastric carcinomas are among the most common cancers in Germany, with approximately 18,000 new cases per year.About 10 years ago, based on results of the Trastuzumab for gastric cancer (ToGA) trial, the addition of the monoclonal antibody trastuzumab
Externí odkaz:
https://doaj.org/article/3a8d470018564dc88e905b8ceaebec60
Autor:
Jens Jürgensen, Michael Pohl
Publikováno v:
Metals, Vol 13, Iss 9, p 1585 (2023)
By utilizing hydrogen as an eco-friendly energy source, many metals are exposed to gaseous (pressurized) hydrogen. High-strength steels with an ultimate tensile strength of 800 MPa and above are especially susceptible to hydrogen-induced fracturing,
Externí odkaz:
https://doaj.org/article/9331155c200a4ad79e28556b0c41111e
Autor:
Deepak Vangala, Swetlana Ladigan, Sven T. Liffers, Soha Noseir, Abdelouahid Maghnouj, Tina-Maria Götze, Berlinda Verdoodt, Susanne Klein-Scory, Laura Godfrey, Martina K. Zowada, Mario Huerta, Daniel L. Edelstein, Jaime Martinez de Villarreal, Miriam Marqués, Jörg Kumbrink, Andreas Jung, Tobias Schiergens, Jens Werner, Volker Heinemann, Sebastian Stintzing, Doris Lindoerfer, Ulrich Mansmann, Michael Pohl, Christian Teschendorf, Christiane Bernhardt, Heiner Wolters, Josef Stern, Selami Usta, Richard Viebahn, Jacob Admard, Nicolas Casadei, Stefan Fröhling, Claudia R. Ball, Jens T. Siveke, Hanno Glimm, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-25 (2021)
Abstract Background The development of secondary resistance (SR) in metastatic colorectal cancer (mCRC) treated with anti-epidermal growth factor receptor (anti-EGFR) antibodies is not fully understood at the molecular level. Here we tested in vivo s
Externí odkaz:
https://doaj.org/article/cfb1d471a175414a977bd791dd7bb74a
Autor:
Moritz Neubauer, Julia Genßler, Vincent Radmann, Fleming Kohlenberg, Michael Pohl, Kurt Böhme, Karsten Knobloch, Ennes Sarradj, Klaus Höschler, Niels Modler, Lars Enghardt
Publikováno v:
Aerospace, Vol 10, Iss 1, p 5 (2022)
This paper presents a combined experimental and numerical investigation on a novel liner concept for enhanced low-frequency and broadband acoustic attenuation. In particular, two different realizations, derived from conventional Helmholtz resonators
Externí odkaz:
https://doaj.org/article/d69d0f900dd84db3b3cc0972ca4f6881
Publikováno v:
Polymers, Vol 14, Iss 23, p 5285 (2022)
Due to current developments in jet engine design, the acoustic performance of conventional acoustic liners needs to be improved with respect to lower frequency spectrums and broadband absorption. In this context, the present study aimed to determine
Externí odkaz:
https://doaj.org/article/6c66f456a83b4e9a8608aace3d0e405d
Publikováno v:
Die Gastroenterologie. 17:387-392
Autor:
Susanne Klein-Scory, Ingo Wahner, Marina Maslova, Yosef Al-Sewaidi, Michael Pohl, Thomas Mika, Swetlana Ladigan, Roland Schroers, Alexander Baraniskin
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Treatment options for patients with metastatic colorectal cancer (mCRC) are limited. This particularly affects the largest group of patients with RAS mutations, who are considered ineligible for therapy with antiEGFR antibodies. In this liquid biopsy
Externí odkaz:
https://doaj.org/article/75c9a8b75e3c40dfad0c04f50162d217
Autor:
Susanne Klein-Scory, Marina Maslova, Michael Pohl, Christina Eilert-Micus, Roland Schroers, Wolff Schmiegel, Alexander Baraniskin
Publikováno v:
Translational Oncology, Vol 11, Iss 2, Pp 213-220 (2018)
PURPOSE: Despite therapeutic improvements, all patients with nonresectable metastatic colorectal cancer (mCRC) acquire resistance to treatment probably due to the growth of mutated clones. In contrast to tissue-based studies, liquid biopsies have ena
Externí odkaz:
https://doaj.org/article/fcd49904db374070ad77b5d3ddd2dea9