Výsledky vyhledávání - "Michael, Pierce"

Akademický článek

Clinical Outcomes of Eravacycline in Patients Treated Predominately for Carbapenem-Resistant Acinetobacter baumannii

Publikováno v: Microbiology Spectrum, Vol 10, Iss 5 (2022)

ABSTRACT Forty-six patients were treated with eravacycline (ERV) for Acinetobacter baumannii infections, where 69.5% of isolates were carbapenem resistant (CRAB). Infections were primarily pulmonary (58.3%), and most patients received combination the

Externí odkaz: https://doaj.org/article/3784b810c9054f3dafb994059224b8c7

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Akademický článek

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Bordetella bronchiseptica Co-Infection in a Stem Cell Transplant Patient

Autor: Michael Pierce, Wendy Slipke, Mark Biagi

Publikováno v: Antibiotics, Vol 11, Iss 9, p 1200 (2022)

Bordetella bronchiseptica infections may be overlooked by clinicians due to the uncommon encounter of this pathogen in humans and common isolation of co-pathogens. However, the isolation of B. bronchiseptica in immunocompromised individuals may repre

Externí odkaz: https://doaj.org/article/49225024fb9a45c480a6a68f09a82fcc

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Akademický článek

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Human Intelectin-1 Promotes Cellular Attachment and Neutrophil Killing of Streptococcus pneumoniae in a Serotype-Dependent Manner

Autor: Silke Andresen, Kayla Fantone, Digantkumar Chapla, Balázs Rada, Kelley W. Moremen, Michael Pierce, Christine M. Szymanski

Publikováno v: Infect Immun

Human intelectin-1 (hIntL-1) is a secreted glycoprotein capable of binding exocyclic 1,2-diols within surface glycans of human pathogens such as Streptococcus pneumoniae, Vibrio cholerae, and Helicobacter pylori. For the latter, lectin binding was sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46e97029b3839175f2f0060dc8653a8
https://pubmed.ncbi.nlm.nih.gov/35499339

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Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design

Autor: Xiao-Ping Li, Bin Cao, Jacques Roberge, Nilgun E. Tumer, David Augeri, Anastasiia M Tsymbal, Michael Pierce, Jennifer Nielsen Kahn, Rajesh K. Harijan

Publikováno v: Journal of medicinal chemistry. 64(20)

Ricin toxin A subunit (RTA) is the catalytic subunit of ricin, which depurinates an adenine from the sarcin/ricin loop in eukaryotic ribosomes. There are no approved inhibitors against ricin. We used a new strategy to disrupt RTA-ribosome interaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98582b494a2052d8b5837c327e69e18
https://pubmed.ncbi.nlm.nih.gov/34648707

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Pelvic Shadowing as a Diagnostic Predictor of Orthopedic Pathology in Orthopedic Trauma Patients

Autor: Michael Pierce Ebaugh, Braden J Passias, Brian Skura, Daniel DeGenova, Benjamin C. Taylor, Adam Hoffman, Joseph Scheschuk

Publikováno v: Cureus

Introduction The Throckmorton sign, or John Thomas sign, is a well-established orthopedic eponym, anecdotally used in orthopedic surgery to correlate the direction of male genitalia, observed on a pelvic radiograph, with the laterality of an associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0601bb9f14f57b0064322bf6d78e8448
http://europepmc.org/articles/PMC8502435

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