Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Michael, Nyberg"'
Autor:
Per Lav Madsen, Casper Sejersen, Michael Nyberg, Martin Heyn Sørensen, Ylva Hellsten, Peter Gaede, Annemie Stege Bojer
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The significant morbidity and premature mortality of type 2 diabetes mellitus (T2DM) is largely associated with its cardiovascular consequences. Focus has long been on the arterial atheromatosis of DM giving rise to early stroke and myocardial infarc
Externí odkaz:
https://doaj.org/article/3c164a5efb1040319e3b76a208510bd2
Autor:
Julian C. Bachmann, Jeppe E. Kirchhoff, Julia E. Napolitano, Steve Sorota, William M. Gordon, Nicole Feric, Roozbeh Aschar‐Sobbi, Juan Lv, Zhiyou Cao, Ken Coppieters, Giulia Borghetti, Michael Nyberg
Publikováno v:
Experimental Physiology, Vol 108, Iss 9, Pp 1172-1188 (2023)
Abstract The role of C‐type natriuretic peptide (CNP) in the regulation of cardiac function in humans remains to be established as previous investigations have been confined to animal model systems. Here, we used well‐characterized engineered car
Externí odkaz:
https://doaj.org/article/924e12c5295147d397da437fed3fabe0
Autor:
Héléne T. Cronjé, Ville Karhunen, G. Kees Hovingh, Ken Coppieters, Jens O. Lagerstedt, Michael Nyberg, Dipender Gill
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect
Externí odkaz:
https://doaj.org/article/0d9080e5d8094a21b18b925771ec0af9
Autor:
Ditte Marie Jensen, Gry Freja Skovsted, Mathilde Frederikke Bjørn Bonde, Jacob Fog Bentzon, Bidda Rolin, Grégory Franck, Maria Katarina Elm Ougaard, Louise Marie Voetmann, Julian Christoffer Bachmann, Anna Uryga, Charles Pyke, Rikke Kaae Kirk, Henning Hvid, Lotte Bjerre Knudsen, Jens Lykkesfeldt, Michael Nyberg
Publikováno v:
Atherosclerosis Plus, Vol 49, Iss , Pp 32-41 (2022)
Background and aims: Randomized clinical studies have shown a reduction in cardiovascular outcomes with glucagon-like peptide 1 receptor agonist (GLP-1RA) treatment with the hypothesized mechanisms being an underlying effect on atherosclerosis. Here,
Externí odkaz:
https://doaj.org/article/f47cfbc975fb429383e07990f4efcd05
Autor:
Bianca E. Suur, Melody Chemaly, Moritz Lindquist Liljeqvist, Djordje Djordjevic, Markus Stenemo, Otto Bergman, Eva Karlöf, Mariette Lengquist, Jacob Odeberg, Eva Hurt-Camejo, Per Eriksson, Daniel F.J. Ketelhuth, Joy Roy, Ulf Hedin, Michael Nyberg, Ljubica Matic
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Proprotein convertase subtilisin/kexins (PCSKs) constitute a family of nine related proteases: PCSK1-7, MBTPS1, and PCSK9. Apart from PCSK9, little is known about PCSKs in cardiovascular disease. Here, we aimed to investigate the expression landscape
Externí odkaz:
https://doaj.org/article/45afed7402f6409196564f46ad266d9a
Autor:
Michael Nyberg, Andrew M. Jones
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Skeletal muscle is one of the most dynamic metabolic organs as evidenced by increases in metabolic rate of >150-fold from rest to maximal contractile activity. Because of limited intracellular stores of ATP, activation of metabolic pathways is requir
Externí odkaz:
https://doaj.org/article/80c3a9903feb402daf3b50a51f143fe6
Autor:
Vanessa Isabell Jurtz, Grethe Skovbjerg, Casper Gravesen Salinas, Urmas Roostalu, Louise Pedersen, Jacob Hecksher-Sørensen, Bidda Rolin, Michael Nyberg, Martijn van de Bunt, Camilla Ingvorsen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Complications of atherosclerosis are the leading cause of morbidity and mortality worldwide. Various genetically modified mouse models are used to investigate disease trajectory with classical histology, currently the preferred methodology t
Externí odkaz:
https://doaj.org/article/307dce623c614724b179921559a4ac86
Autor:
Julian C. Bachmann, Simon J. Baumgart, Anna K. Uryga, Markus H. Bosteen, Giulia Borghetti, Michael Nyberg, Kate M. Herum
Publikováno v:
Cells, Vol 11, Iss 10, p 1657 (2022)
Patients with heart failure with preserved ejection fraction (HFpEF) and atherosclerosis-driven coronary artery disease (CAD) will have ongoing fibrotic remodeling both in the myocardium and in atherosclerotic plaques. However, the functional consequ
Externí odkaz:
https://doaj.org/article/77ce7afa2de14dc187aab4dcac29f4b3
Autor:
Mukesh Punjabi, Alexandra Kosareva, Lifen Xu, Amanda Ochoa-Espinosa, Sarah Decembrini, Georg Hofmann, Samira Wyttenbach, Bidda Rolin, Michael Nyberg, Beat A. Kaufmann
Publikováno v:
JACC: Basic to Translational Science. 8:189-200
Autor:
Michael Nyberg, Dijana Terzic, Trine P Ludvigsen, Peter D Mark, Natasha B Michaelsen, Steen Z Abildstrøm, Mads Engelmann, A Mark Richards, Jens P Goetze
Publikováno v:
Endocrine Reviews. 44:379-392
Measurement of natriuretic peptides (NPs) has proven its clinical value as biomarker, especially in the context of heart failure (HF). In contrast, a state of partial NP deficiency appears integral to several conditions in which lower NP concentratio