Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Michael, Merker"'
Autor:
Catrin Heim, Leonie Hartig, Nadine Weinelt, Laura M. Moser, Emilia Salzmann-Manrique, Michael Merker, Winfried S. Wels, Torsten Tonn, Peter Bader, Jan-Henning Klusmann, Sjoerd J.L. van Wijk, Eva Rettinger
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200802- (2024)
Treatment resistance and immune escape are hallmarks of metastatic rhabdomyosarcoma (RMS), underscoring the urgent medical need for therapeutic agents against this disease entity as a key challenge in pediatric oncology. Chimeric antigen receptor (CA
Externí odkaz:
https://doaj.org/article/cfcc688602004da1992f3e649b5c4ffd
Autor:
Catrin Heim, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Torsten Tonn, Winfried S. Wels, Elise Gradhand, Evelyn Ullrich, Michael T. Meister, Marian Groot Koerkamp, Frank C. P. Holstege, Jarno Drost, Jan-Henning Klusmann, Peter Bader, Michael Merker, Eva Rettinger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMetastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic strategies. Applying chimeric antigen receptor (CAR
Externí odkaz:
https://doaj.org/article/a67ec3b12510448385698d63f9fbce7d
Autor:
Michael Merker, Juliane Wagner, Hermann Kreyenberg, Catrin Heim, Laura M. Moser, Winfried S. Wels, Halvard Bonig, Zoltán Ivics, Evelyn Ullrich, Thomas Klingebiel, Peter Bader, Eva Rettinger
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
High-risk rhabdomyosarcoma (RMS) occurring in childhood to young adulthood is associated with a poor prognosis; especially children above the age of 10 with advanced stage alveolar RMS still succumb to the disease within a median of 2 years. The adve
Externí odkaz:
https://doaj.org/article/c9e26cde1be642568cc2b4bdadeffe17
Autor:
Nora Bruns, Lea Y. Willemsen, Katharina Holtkamp, Oliver Kamp, Marcel Dudda, Bernd Kowall, Andreas Stang, Florian Hey, Judith Blankenburg, Hemmen Sabir, Frank Eifinger, Hans Fuchs, Roland Haase, Clemens Andrée, Michael Heldmann, Jenny Potratz, Daniel Kurz, Anja Schumann, Merle Müller-Knapp, Nadine Mand, Claus Doerfel, Peter Dahlem, Tobias Rothoeft, Manuel Ohlert, Katrin Silkenbäumer, Frank Dohle, Fithri Indraswari, Frank Niemann, Peter Jahn, Michael Merker, Nicole Braun, Francisco Brevis Nunez, Matthias Engler, Konrad Heimann, Gerhard K. Wolf, Dominik Wulf, Saskia Hankel, Holger Freymann, Nicolas Allgaier, Felix Knirsch, Martin Dercks, Julia Reinhard, Marc Hoppenz, Ursula Felderhoff-Müser, Christian Dohna-Schwake
Publikováno v:
Children, Vol 9, Iss 3, p 363 (2022)
Children’s and adolescents’ lives drastically changed during COVID lockdowns worldwide. To compare accident- and injury-related admissions to pediatric intensive care units (PICU) during the first German COVID lockdown with previous years, we con
Externí odkaz:
https://doaj.org/article/027d9160167347539f8a757baf62b1cc
Autor:
Annekathrin Heinze, Beatrice Grebe, Melanie Bremm, Sabine Huenecke, Tasleem Ah. Munir, Lea Graafen, Jochen T. Frueh, Michael Merker, Eva Rettinger, Jan Soerensen, Thomas Klingebiel, Peter Bader, Evelyn Ullrich, Claudia Cappel
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neuroblastoma (NB) is the most common solid extracranial tumor in childhood. Despite therapeutic progress, prognosis in high-risk NB is poor and innovative therapies are urgently needed. Therefore, we addressed the potential cytotoxic capacity of int
Externí odkaz:
https://doaj.org/article/439d2ee84c6d456f9f5a2cce5888bc1f
Autor:
Melanie Bremm, Lisa-Marie Pfeffermann, Claudia Cappel, Verena Katzki, Stephanie Erben, Sibille Betz, Andrea Quaiser, Michael Merker, Halvard Bonig, Michael Schmidt, Thomas Klingebiel, Peter Bader, Sabine Huenecke, Eva Rettinger
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cytokine-induced killer (CIK) cells are an immunotherapeutic approach to combat relapse following allogeneic hematopoietic stem cell transplantation (HSCT) in acute leukemia or myelodysplastic syndrome (MDS) patients. Prompt and sequential administra
Externí odkaz:
https://doaj.org/article/2b410e20b4ca4cdc83f38cb8aef2ef96
Autor:
Nora Bruns, Lea Willemsen, Andreas Stang, Bernd Kowall, Katharina Holtkamp, Oliver Kamp, Marcel Dudda, Florian Hey, Florian Hoffmann, Judith Blankenburg, Frank Eifinger, Hans Fuchs, Roland Haase, Jan Baier, Clemens Andrée, Michael Heldmann, Vanessa Maldera, Jenny Potratz, Daniel Kurz, Nadine Mand, Claus Doerfel, Tobias Rothoeft, Michel Schultz, Manuel Ohlert, Katrin Silkenbäumer, Thomas Boesing, Fithri Indraswari, Frank Niemann, Peter Jahn, Michael Merker, Nicole Braun, Francisco Brevis Nunez, Matthias Engler, Konrad Heimann, Milian Brasche, Gerhard Wolf, Holger Freymann, Martin Dercks, Marc Hoppenz, Ursula Felderhoff-Müser, Christian Dohna-Schwake
Publikováno v:
Pediatrics. 150
BACKGROUND AND OBJECTIVES The worldwide severe acute respiratory syndrome coronavirus 2 pandemic challenges adolescents’ mental health. In this study, we aim to compare the number of pediatric ICU (PICU) admissions after suicide attempts during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5cc990979953b2bad91e13e4273cb8
https://doi.org/10.1542/peds.2021-055973
https://doi.org/10.1542/peds.2021-055973
Autor:
Eva Rettinger, Sabine Huenecke, Halvard Bonig, Michael Merker, Andrea Jarisch, Jan Soerensen, Andre Willasch, Gesine Bug, Ansgar Schulz, Thomas Klingebiel, Peter Bader
Publikováno v:
Haematologica, Vol 101, Iss 4 (2016)
Externí odkaz:
https://doaj.org/article/e8f4b4f76bad44538e010653e59a9044
Autor:
Judith Blankenburg, Martin Dercks, Felix Knirsch, Nicolas Allgaier, Daniel Kurz, Hans Fuchs, Merle Mueller-Knapp, Katharina Holtkamp, Manuel Ohlert, Frank Dohle, Oliver Kamp, Peter Jahn, Gerhard Wolf, Holger Freymann, Clemens Andree, Claudia Holborn, Tobias Rothoeft, Roland Haase, Hemmen Sabir, Nora Bruns, Bernd Kowall, Andreas Stang, Matthias Engler, Nadine Mand, Marc Hoppenz, Frank Eifinger, Nicole Braun, Dominik Wulf, Anja Schumann, Michael Heldmann, Francisco Brevis Nuñez, Florian Hey, Julia Reinhard, Peter Dahlem, Christian Dohna-Schwake, Lea Yvonne Willemsen, Konrad Heimann, Katrin Silkenbaeumer, Michael Merker, Ursula Felderhoff-Mueser, Marcel Dudda, Jenny Potratz, Fithri Indraswari, Claus Doerfel, Frank Niemann
ObjectiveTo compare the number of accident- and injury-related admissions to pediatric intensive care units (PICU) during the first German COVID-19 lockdown with previous years. To investigate if shifts in types of accidents or injuries occurred, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830417f733e0a3a5f35ad27cd0cd9074
https://doi.org/10.1101/2021.08.06.21261728
https://doi.org/10.1101/2021.08.06.21261728
Autor:
Eva Rettinger, Peter Bader, Jan Sörensen, Michael Merker, Annekathrin Heinze, Michael Torsten Meister, Andrea Jarisch, Claudia Cappel, Melanie Bremm, Thomas Klingebiel, Sabine Huenecke
Publikováno v:
Oncotarget
Prognosis of refractory childhood cancers despite multimodal treatment strategies remains poor. Here, we report a single center experience encountered in 18 patients with refractory solid malignancies treated with adoptive cellular immunotherapy (ACI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc42a1ce1b9b55cf37201e22d4c65a32
http://europepmc.org/articles/PMC6817438
http://europepmc.org/articles/PMC6817438