Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Michael, Melnick"'
Publikováno v:
IEEE Transactions on Industry Applications. 58:4261-4270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd852a04142d9bb522b6f76f0c155bb
https://doi.org/10.1109/tia.2022.3167991
https://doi.org/10.1109/tia.2022.3167991
Autor:
Matthew Cavanaugh, Jingyi Yang, Berkeley Fahrenthold, Elizabeth Saionz, Michael Melnick, Marisa Carrasco, Duje Tadin, Krystel Huxlin
Publikováno v:
Journal of Vision. 22:3718
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::658a48bf8d85b365631badd08b3db1fe
https://doi.org/10.1167/jov.22.14.3718
https://doi.org/10.1167/jov.22.14.3718
Autor:
Lutz Kockel, Kimberly S Kerr, Michael Melnick, Katja Brückner, Matthias Hebrok, Norbert Perrimon
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000990 (2010)
Akt represents a nodal point between the Insulin receptor and TOR signaling, and its activation by phosphorylation controls cell proliferation, cell size, and metabolism. The activity of Akt must be carefully balanced, as increased Akt signaling is f
Externí odkaz:
https://doaj.org/article/bb54d020547f433fb102547d41b03397
Autor:
Allan Scott Wagman, Sara Lopez, Lloyd J. Simons, James B. Aggen, Ryan Cirz, Glenn McEnroe, Christina R. Harris, Adam Aaron Goldblum, Heinz E. Moser, Ricky D. Gaston, Michael Melnick, Toni-Jo Poel, M. A. Gómez, George Miller, Martin S. Linsell, Thomas R. Belliotti
Publikováno v:
ChemMedChem. 12:1687-1692
Conformationally constrained tetracyclic fluoroquinolones (FQs) were synthesized and profiled for their microbiological spectrum. The installation of a seven-membered ring between the pyrrolidine substituents and the C8 position on the FQ core scaffo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08be1ae1ed6d3ea6cb5bdcb7a990375c
https://doi.org/10.1002/cmdc.201700426
https://doi.org/10.1002/cmdc.201700426
Autor:
Michael Melnick, Tina Jaskoll
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 103:573-582
Background Congenital cytomegalovirus infection is the major nongenetic cause of sensorineural hearing loss at birth and beyond. Among other pathologies, there is a striking dysplasia/hyperplasia of organ of Corti hair and supporting cells. Methods U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51c10ee298bcfc560f22dcd8e256c18a
https://doi.org/10.1002/bdra.23386
https://doi.org/10.1002/bdra.23386
Autor:
Eileen M. O'Reilly, Gerhard Frey, Jordi Rodon Ahnert, Matthew H. Taylor, Jingsong Zhang, Howard A. Burris, William J. Boyle, Michael Melnick, Wei Chen, Cathy Chang, Jay M. Short, Leslie L. Sharp, Yong Ben, Robert C. Doebele
Publikováno v:
Journal of Clinical Oncology. 36:TPS12126-TPS12126
TPS12126Background: The AXL receptor tyrosine kinase is often highly expressed in certain cancers. AXL appears to sustain resistance to anticancer therapies including chemotherapy, targeted therapy...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e9e0bbd41185cdaf0dd69504d999e61
https://doi.org/10.1200/jco.2018.36.15_suppl.tps12126
https://doi.org/10.1200/jco.2018.36.15_suppl.tps12126
Autor:
Don Emerson, Doh-Yeel Lee, Venkataraman Thanabal, Michael Melnick, J. Richard Miller, Ronald W. Sarver, Jeff Ohren, Manjinder S. Lall, Charles Francis Donovan
Publikováno v:
Chemical Biology & Drug Design. 75:444-454
High-throughput screening is utilized by pharmaceutical researchers and, increasingly, academic investigators to identify agents that act upon enzymes, receptors, and cellular processes. Screening hits include molecules that specifically bind the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b214fe8e405df9a95986c60e3e95b5b2
https://doi.org/10.1111/j.1747-0285.2010.00957.x
https://doi.org/10.1111/j.1747-0285.2010.00957.x
Autor:
Tina Jaskoll, Pablo Bringas, George Abichaker, Khine Htet, Scott Morita, Michael Melnick, Parish P. Sedghizadeh
Publikováno v:
Cells Tissues Organs. 192:221-239
Of the approximately 8,400 children born each year in the US with cytomegalovirus (CMV)-induced birth defects, more than one third exhibit hypoplasia and hypocalcification of tooth enamel. Our prior studies indicated that CMV severely delayed, but di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a53da93df6c235e5a73f2012171ba7f
https://doi.org/10.1159/000314909
https://doi.org/10.1159/000314909
Autor:
Igor Mochalkin, Sandra Lightle, Michael Melnick, Craig Banotai, Yaqi Zhu, Cindy Spessard, Nickolay Y. Chirgadze, Laura McDowell, Jeffrey F. Ohren
Publikováno v:
Protein Science. 16:2657-2666
N-Acetylglucosamine-1-phosphate uridyltransferase (GlmU) catalyzes the first step in peptidoglycan biosynthesis in both Gram-positive and Gram-negative bacteria. The products of the GlmU reaction are essential for bacterial survival, making this enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d11e75da8942d5d60294a494af00ed
https://doi.org/10.1110/ps.073135107
https://doi.org/10.1110/ps.073135107
Publikováno v:
Journal of Immunological Methods. 305:59-66
Our understanding of the mechanisms by which BCR-ABL drives CML is based, in part, on the use of model cell lines such as the K562 cell line. However, the BCR-ABL translocation may occur via a number of different junction points. In addition, CML is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7000f36f1785fd34af2356471ad2cb
https://doi.org/10.1016/j.jim.2005.07.012
https://doi.org/10.1016/j.jim.2005.07.012