Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michael, McArthur"'
Autor:
Adam Pattinson, Sandeep Bahia, Gwénaëlle Le Gall, Christopher J. Morris, Sarah V. Harding, Michael McArthur
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Burkholderia pseudomallei is the causative agent of the tropical disease, melioidosis. It is intrinsically resistant to many antimicrobials and treatment requires an onerous regimen of intravenous and orally administered drugs. Relapse of disease and
Externí odkaz:
https://doaj.org/article/0101f21e0e53457f82fc61a592924bb5
Autor:
Simona Di Blasio, Maria Clarke, Charlotte K. Hind, Masanori Asai, Louis Laurence, Angelica Benvenuti, Mahnoor Hassan, Dorothy Semenya, DeDe Kwun-Wai Man, Victoria Horrocks, Giorgia Manzo, Sarah Van Der Lith, Carolyn Lam, Eugenio Gentile, Callum Annette, Janine Bosse, Yanwen Li, Barry Panaretou, Paul R. Langford, Brian D. Robertson, Jenny K. W. Lam, J. Mark Sutton, Michael McArthur, A. James Mason
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT 12-Bis-THA Cl2 [12,12′-(dodecane-1,12-diyl)-bis-(9-amino-1,2,3,4-tetrahydroacridinium) chloride] is a cationic bolalipid adapted from dequalinium chloride (DQC), a bactericidal anti-infective indicated for bacterial vaginosis (BV). Here, w
Externí odkaz:
https://doaj.org/article/8625d87284694eff9568dd55269bba7a
Autor:
Alan Hibbitts, Ainhoa Lucía, Inés Serrano-Sevilla, Laura De Matteis, Michael McArthur, Jesús M de la Fuente, José A Aínsa, Fabrice Navarro
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0220684 (2019)
Bacterial resistance to antibiotics is widely regarded as a major public health concern with last resort MRSA treatments like vancomycin now encountering resistant strains. TFDs (Transcription Factor Decoys) are oligonucleotide copies of the DNA-bind
Externí odkaz:
https://doaj.org/article/1f54707cacf14147862f50babde9db7f
Autor:
Simona, Di Blasio, Maria, Clarke, Charlotte K, Hind, Masanori, Asai, Louis, Laurence, Angelica, Benvenuti, Mahnoor, Hassan, Dorothy, Semenya, DeDe Kwun-Wai, Man, Victoria, Horrocks, Giorgia, Manzo, Sarah, Van Der Lith, Carolyn, Lam, Eugenio, Gentile, Callum, Annette, Janine, Bosse, Yanwen, Li, Barry, Panaretou, Paul R, Langford, Brian D, Robertson, Jenny K W, Lam, J Mark, Sutton, Michael, McArthur, A James, Mason
Publikováno v:
mSphere.
12-Bis-THA Cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::288db37a7dc385e63136430bb1b005af
https://pubmed.ncbi.nlm.nih.gov/36511707
https://pubmed.ncbi.nlm.nih.gov/36511707
Autor:
Hom Lal Shrestha, Michael McArthur, Robyn L Rowe, Joey‐Lynn Wabie, Marion Maar, Jennifer D Walker
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccc21c2cb3a034395bb958824be203b3
https://doi.org/10.1002/alz.062295
https://doi.org/10.1002/alz.062295
Autor:
Hom Lal Shrestha, Michael McArthur, Robyn L Rowe, Joey‐Lynn Wabie, Marion Maar, Jennifer D Walker
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9476fd2e9775e02f183403a7265ac2f9
https://doi.org/10.1002/alz.051066
https://doi.org/10.1002/alz.051066
Autor:
Justyna Kozlowska, Louic S Vermeer, Geraint B Rogers, Nabila Rehnnuma, Sarah-Beth T A Amos, Garrit Koller, Michael McArthur, Kenneth D Bruce, A James Mason
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004104 (2014)
Obtaining an in-depth understanding of the arms races between peptides comprising the innate immune response and bacterial pathogens is of fundamental interest and will inform the development of new antibacterial therapeutics. We investigated whether
Externí odkaz:
https://doaj.org/article/7987b2ab62394dd582e30eaa1d411dcf
Autor:
Leopoldo Sitia, Christopher J. Morris, Michael McArthur, Paolo Gasco, Grant N. Wheeler, Ana González-Paredes, Angels Ruyra
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 134:166-177
Novel alternatives to antibiotics are urgently needed for the successful treatment of antimicrobial resistant (AMR) infections. Experimental antibacterial oligonucleotide therapeutics, such as transcription factor decoys (TFD), are a promising approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2362c33a5899d14e704f55d023b2974f
https://doi.org/10.1016/j.ejpb.2018.11.017
https://doi.org/10.1016/j.ejpb.2018.11.017
Publikováno v:
Canadian Journal of Rural Medicine. 27:158
One critical component of any rural community is its healthcare system. Rural healthcare systems are essential as rural communities have worse health outcomes when compared to urban areas. Rural healthcare systems might also have a positive impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d3139624d679b1077d48e8d128fe2d
https://doi.org/10.4103/cjrm.cjrm_70_21
https://doi.org/10.4103/cjrm.cjrm_70_21
Publikováno v:
Access Microbiology. 1
Transcription Factor Decoys (TFDs) are short synthetic oligonucleotides that contain the binding site for specific bacterial transcription factors. When translocated into bacterial cytoplasm they can rapidly kill cells when targeted against essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3354f6440732aa54d89d3693219c02ec
https://doi.org/10.1099/acmi.ac2019.po0437
https://doi.org/10.1099/acmi.ac2019.po0437