Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Michael, Kurowski"'
Autor:
Peter Kotzerke, Christoph Stephan, Martin Stürmer, Markus Bickel, Pavel Khaykin, Michael Kurowski, Nils von Hentig, Reinhard Brodt, Gabi Nisius, Annette Haberl
Publikováno v:
Therapeutic Drug Monitoring. 36:192-201
Objective Lopinavir/ritonavir plus nucleoside reverse transcriptase inhibitors is one standard antiretroviral therapy regimen, both in patients with HIV alone and coinfected with hepatitis B or C. Our objective was to investigate whether hepatitis co
Autor:
Glynn A. Morrish, Gerd Faetkenheuer, Bruce Green, Markus Bickel, Michael Kurowski, Yvon van Delft, Thomas N. Kakuda, Andrew Hill, Giovanni Di Perri
Publikováno v:
HIV Clinical Trials. 14:92-98
Etravirine is currently approved for HIV treatment-experienced patients at a dose of 200 mg twice daily. The long terminal elimination half-life of etravirine should support once-daily dosing.In the double-blind 48-week SENSE trial, 157 antiretrovira
Autor:
Thomas A. Lutz, Wolf O. Bechstein, Nils von Hentig, Johannes Kuetscher, Evrim Anadol, Jürgen K. Rockstroh, Markus Bickel, Hans Reinhard Brodt, Wolf Peter Hofmann, Martin Vogel, C. Moench, Michael Kurowski, Tessa Lennemann
Publikováno v:
Journal of Antimicrobial Chemotherapy. 65:999-1004
The number of HIV-infected patients receiving orthotopic liver transplantation (OLTX) is increasing. One major challenge is the severe drug-drug interactions between immunosuppressive drugs such as tacrolimus and ritonavir-boosted HIV-1 protease inhi
Autor:
Rose Kabasinguzi, Michael Kurowski, Andrea Kunz, Charlotte Kloft, Kizito Mugenyi, Monika Frank, Gundel Harms, Astrid Weidenhammer
Publikováno v:
Journal of Antimicrobial Chemotherapy. 63:170-177
OBJECTIVES: Nevirapine is widely used in the developing world for the prevention of mother-to-child transmission (PMTCT) of HIV. A single mutation in the HIV genome is sufficient to lead to significant nevirapine resistance. Persistence of low-level
Autor:
Angelika Mayer, Shirin Simo, Kizito Mugenyi, Gundel Harms, Moses Ali, Heiko Karcher, Andrea Kunz, Michael Kurowski
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 44:562-565
Background: Intrapartum transmission of HIV has been reported to be associated with HIV in oropharyngeal secretions (OPSs) of the child. In this study, we analyze the frequency of intrapartum transmission after mucosal exposure to HIV after administr
Autor:
Michael Kurowski, Sebastian Harder, Timo Wolf, Nils von Hentig, Schlomo Staszewski, Thomas A. Lutz, S Klauke, Brenda Dauer, Carsten Rottmann, Bruno G. Oertel, Axel Müller
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:1431-1439
The objective of this study was to evaluate the pharmacokinetics of atazanavir (ATV), saquinavir (SQV), and ritonavir (RTV) in a boosted double-protease inhibitor (PI) therapy regimen without reverse transcriptase inhibitors (RTIs). The study design
Autor:
Annette Haberl, Michael Kurowski, Schlomo Staszewski, Christoph Stephan, Brenda Dauer, Carsten Rottmann, Amina Carlebach, N von Hentig
Publikováno v:
International Journal of STD & AIDS. 18:81-84
Gastrointestinal intolerance is a limitation of boosted saquinavir antiretroviral treatment. We present three HIV-infected individuals whose severe toxicity symptoms started directly after initiation of a standard dose saquinavir hard-gel capsule-con
Autor:
Edward P. Acosta, Mario Regazzi, David M. Burger, Courtney V. Fletcher, David Back, Marta Boffito, Gilles Peytavin, Carlo Federico Perno, Rodolphe Garaffo, Charles Flexner, Giorgio Gatti, Michael Kurowski
Publikováno v:
Antiviral Therapy. 10:469-477
The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) provide a framework for t
Autor:
Marta Boffito, Rodolphe Garaffo, David Back, Gilles Peytavin, Giorgio Gatti, Edward P. Acosta, Michael Kurowski, Mario Regazzi, Carlo Federico Perno, Courtney V. Fletcher, David M. Burger, Charles Flexner
Publikováno v:
Scopus-Elsevier
Antiviral Therapy, 10, 3, pp. 375-92
Europe PubMed Central
Antiviral Therapy, 10, 375-92
Antiviral Therapy, 10, 3, pp. 375-92
Europe PubMed Central
Antiviral Therapy, 10, 375-92
The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors and protease inhibitors provide a framework for the implementati
Autor:
Andrew F. Hill, Graeme Moyle, Brian Gazzard, Mark Nelson, Marta Boffito, Andrew A Benzie, Guido Kruse, Anton Pozniak, Michael Kurowski
Publikováno v:
AIDS. 18:1291-1297
Objective: To determine the pharmacokinetics of saquinavir hard-gel capsules/ ritonavir/atazanavir co-administered once daily at 1600/100/300 mg in HIV-infected individuals. Methods: Eighteen patients receiving saquinavir/ritonavir switched to 1600/1