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Autor:
Whitney N. Wood, Miguel Angel Rubio, Lorenzo Eugenio Leiva, Gregory J. Phillips, Michael Ibba
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Bacterial antibiotic persistence is a phenomenon where bacteria are exposed to an antibiotic and the majority of the population dies while a small subset enters a low metabolic, persistent, state and are able to survive. Once the antibiotic is remove
Externí odkaz:
https://doaj.org/article/779b5288bb174b258126710f0566db3a
Autor:
Lorenzo Eugenio Leiva, Sara Elgamal, Sebastian A. Leidel, Omar Orellana, Michael Ibba, Assaf Katz
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
IntroductionThe response of enterobacteria to oxidative stress is usually considered to be regulated by transcription factors such as OxyR and SoxR. Nevertheless, several reports have shown that under oxidative stress the levels, modification and ami
Externí odkaz:
https://doaj.org/article/834f1fceda4f435ebbea296a97d0c398
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Bacterial antibiotic persistence is a transient physiological state wherein cells become dormant and thereby evade being killed by antibiotics. Once the antibiotic is removed, bacterial persisters are able to resuscitate and repopulate.
Externí odkaz:
https://doaj.org/article/c1ef9d2b186d43299520d29a1d1b62e9
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/a8e295702af64ddfa6610f3a77f02bfd
Autor:
Lorenzo Eugenio Leiva, Andrea Pincheira, Sara Elgamal, Sandra D. Kienast, Verónica Bravo, Johannes Leufken, Daniela Gutiérrez, Sebastian A. Leidel, Michael Ibba, Assaf Katz
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Bacterial oxidative stress responses are generally controlled by transcription factors that modulate the synthesis of RNAs with the aid of some sRNAs that control the stability, and in some cases the translation, of specific mRNAs. Here, we report th
Externí odkaz:
https://doaj.org/article/6c620f96ab9f47838b6afc84336ae310
Autor:
Paul Kelly, Fatemeh Hadi-Nezhad, Dennis Y Liu, Travis J Lawrence, Roger G Linington, Michael Ibba, David H Ardell
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 2, p e0007983 (2020)
The development of chemotherapies against eukaryotic pathogens is especially challenging because of both the evolutionary conservation of drug targets between host and parasite, and the evolution of strain-dependent drug resistance. There is a strong
Externí odkaz:
https://doaj.org/article/2bcd2afbb04e4533845b81c890cb991e
Autor:
Supreet K. Sahai, Rebecca E. Steiner, Margaret G. Au, John M. Graham, Noriko Salamon, Michael Ibba, Tyler M. Pierson
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 5, Iss 9, Pp 1128-1133 (2018)
Abstract Mutations in FARS2, the gene encoding the mitochondrial phenylalanine‐tRNA synthetase (mtPheRS), have been linked to a range of phenotypes including epileptic encephalopathy, developmental delay, and motor dysfunction. We report a 9‐year
Externí odkaz:
https://doaj.org/article/43e4647c5fe14af28f7805a0655f19d9
Publikováno v:
Trends in Biochemical Sciences. 47:631-634
Written and oral communication are skills graduate students often request training in and supervisors often bemoan the lack of. We describe an approach to address this training gap using an instructional model that integrates experienced research-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55bda518d81b6a92f9db64ecf43b54e
https://doi.org/10.1016/j.tibs.2022.03.019
https://doi.org/10.1016/j.tibs.2022.03.019
Autor:
Paul Kelly, Nicholas Backes, Kyle Mohler, Christopher Buser, Arundhati Kavoor, Jesse Rinehart, Gregory Phillips, Michael Ibba
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Mechanisms have evolved to prevent errors in replication, transcription, and translation of genetic material, with translational errors occurring most frequently. Errors in protein synthesis can occur at two steps, during tRNA aminoacylation
Externí odkaz:
https://doaj.org/article/04243a06d1b34fd4a575aaced56d4984