Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael, Härter"'
Autor:
Michael, Härter, Bernd, Kalthof, Martina, Delbeck, Klemens, Lustig, Michael, Gerisch, Simone, Schulz, Raimund, Kast, Daniel, Meibom, Niels, Lindner
Publikováno v:
European journal of medicinal chemistry. 163
The A
Autor:
Johannes-Peter Stasch, Andreas Knorr, Claudia Hirth-Dietrich, Michael Hahn, Michael Härter, Yvonne Keim, Cristina Alonso-Alija, Frank Wunder
Publikováno v:
Arzneimittelforschung. 58:71-80
Liver cirrhosis is a chronic disease with high mortality rate and need for effective pharmacological intervention. The fibrotic remodelling of liver tissue is crucially dependent on hepatic stellate cell activation. Activation of hepatic stellate cel
Autor:
Klaus Urbahns, Christoph Gerdes, Klemens Lustig, Beatrix Stelte-Ludwig, Ulf Brüggemeier, Andrea Vaupel, Delf Schmidt, Jörg Keldenich, Markus Albers, Michael Härter, Hideki Tsujishita
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6151-6154
Vitronectin receptor (alpha(V)beta(3)) antagonists have been implicated as a possible new treatment of restenosis following balloon angioplasty. In this work we investigate a series of novel arginine mimetic scaffolds leading to new insight of the al
Autor:
Beatrix Stelte-Ludwig, Christoph Gerdes, Markus Albers, Delf Schmidt, Michael Härter, Ulf Brüggemeier, Klaus Urbahns, Andrea Vaupel
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:205-208
Vitronectin receptor (α V β 3 ) antagonism has been implicated as a mechanism for the treatment of restenosis following balloon angioplasty. In this work we present results from screening of a focused combinatorial library based on a biphenyl moiet
Autor:
Cristina Alonso-Alija, Michael Härter, Yvonne Keim, Johannes-Peter Stasch, Michael Hahn, Frank Wunder, Andreas Knorr, Claudia Hirth-Dietrich
Publikováno v:
BMC Pharmacology. 5
Background Liver fibrosis and cirrhosis are late complications common to liver diseases of different etiology such as viral hepatitis and alcoholic liver disease. Irrespective of the initial cause of liver disease, activation of hepatic stellate cell
Autor:
Beatrix Stelte-Ludwig, Markus Albers, Ulf Brüggemeier, Klaus Urbahns, Michael Härter, Andrea Vaupel, Delf Schmidt, Hideki Tsujishita, Christoph Gerdes
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(6)
Vitronectin receptor (alpha(V)beta(3)) antagonism has been implicated in a variety of disease states, like restenosis, osteoporosis and cancer. In this work, we present the development of a novel class of biphenyl vitronectin receptor antagonists. Id