Zobrazeno 1 - 10
of 509
pro vyhledávání: '"Michael, Goggins"'
Autor:
Alison P. Klein, Brian M. Wolpin, Harvey A. Risch, Rachael Z. Stolzenberg-Solomon, Evelina Mocci, Mingfeng Zhang, Federico Canzian, Erica J. Childs, Jason W. Hoskins, Ashley Jermusyk, Jun Zhong, Fei Chen, Demetrius Albanes, Gabriella Andreotti, Alan A. Arslan, Ana Babic, William R. Bamlet, Laura Beane-Freeman, Sonja I. Berndt, Amanda Blackford, Michael Borges, Ayelet Borgida, Paige M. Bracci, Lauren Brais, Paul Brennan, Hermann Brenner, Bas Bueno-de-Mesquita, Julie Buring, Daniele Campa, Gabriele Capurso, Giulia Martina Cavestro, Kari G. Chaffee, Charles C. Chung, Sean Cleary, Michelle Cotterchio, Frederike Dijk, Eric J. Duell, Lenka Foretova, Charles Fuchs, Niccola Funel, Steven Gallinger, J. Michael M. Gaziano, Maria Gazouli, Graham G. Giles, Edward Giovannucci, Michael Goggins, Gary E. Goodman, Phyllis J. Goodman, Thilo Hackert, Christopher Haiman, Patricia Hartge, Manal Hasan, Peter Hegyi, Kathy J. Helzlsouer, Joseph Herman, Ivana Holcatova, Elizabeth A. Holly, Robert Hoover, Rayjean J. Hung, Eric J. Jacobs, Krzysztof Jamroziak, Vladimir Janout, Rudolf Kaaks, Kay-Tee Khaw, Eric A. Klein, Manolis Kogevinas, Charles Kooperberg, Matthew H. Kulke, Juozas Kupcinskas, Robert J. Kurtz, Daniel Laheru, Stefano Landi, Rita T. Lawlor, I.-Min Lee, Loic LeMarchand, Lingeng Lu, Núria Malats, Andrea Mambrini, Satu Mannisto, Roger L. Milne, Beatrice Mohelníková-Duchoňová, Rachel E. Neale, John P. Neoptolemos, Ann L. Oberg, Sara H. Olson, Irene Orlow, Claudio Pasquali, Alpa V. Patel, Ulrike Peters, Raffaele Pezzilli, Miquel Porta, Francisco X. Real, Nathaniel Rothman, Ghislaine Scelo, Howard D. Sesso, Gianluca Severi, Xiao-Ou Shu, Debra Silverman, Jill P. Smith, Pavel Soucek, Malin Sund, Renata Talar-Wojnarowska, Francesca Tavano, Mark D. Thornquist, Geoffrey S. Tobias, Stephen K. Van Den Eeden, Yogesh Vashist, Kala Visvanathan, Pavel Vodicka, Jean Wactawski-Wende, Zhaoming Wang, Nicolas Wentzensen, Emily White, Herbert Yu, Kai Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Peter Kraft, Donghui Li, Stephen Chanock, Ofure Obazee, Gloria M. Petersen, Laufey T. Amundadottir
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Genetic variants associated with susceptibility to pancreatic cancer have been identified using genome wide association studies (GWAS). Here, the authors combine data from over 9000 patients and perform a meta-analysis to identify five novel loci lin
Externí odkaz:
https://doaj.org/article/62f48b33d3e24b21a7c8f4e240a960a1
Autor:
Mohamad Dbouk, Bryson W. Katona, Randall E. Brand, Amitabh Chak, Sapna Syngal, James J. Farrell, Fay Kastrinos, Elena M. Stoffel, Marcia Irene Canto, Michael Goggins
Publikováno v:
Journal of Clinical Oncology. 41:1147-1149
Autor:
Helena, Saba, Michael, Goggins
Publikováno v:
Gastroenterology Clinics of North America. 51:561-575
Individuals at increased risk of developing pancreatic cancer, including those with a significant family history of the disease and those with pancreatic cancer susceptibility gene variants, can benefit from pancreas surveillance. Most pancreatic can
Autor:
Tushar D Bhagat, Dagny Von Ahrens, Meelad Dawlaty, Yiyu Zou, Joelle Baddour, Abhinav Achreja, Hongyun Zhao, Lifeng Yang, Brijesh Patel, Changsoo Kwak, Gaurav S Choudhary, Shanisha Gordon-Mitchell, Srinivas Aluri, Sanchari Bhattacharyya, Srabani Sahu, Prafulla Bhagat, Yiting Yu, Matthias Bartenstein, Orsi Giricz, Masako Suzuki, Davendra Sohal, Sonal Gupta, Paola A Guerrero, Surinder Batra, Michael Goggins, Ulrich Steidl, John Greally, Beamon Agarwal, Kith Pradhan, Debabrata Banerjee, Deepak Nagrath, Anirban Maitra, Amit Verma
Publikováno v:
eLife, Vol 8 (2019)
Even though pancreatic ductal adenocarcinoma (PDAC) is associated with fibrotic stroma, the molecular pathways regulating the formation of cancer associated fibroblasts (CAFs) are not well elucidated. An epigenomic analysis of patient-derived and de-
Externí odkaz:
https://doaj.org/article/de3a332d705e4701ab12d60c3c437380
Autor:
Alison P. Klein, Ralph H. Hruban, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, James R. Eshleman, Rachel Karchin, Michael Goggins, Peter P. Zandi, Laura D. Wood, Christopher L. Wolfgang, Yuxuan Wang, Alyssa L. Smith, Andrew D. Rhim, James B. Potash, Mehdi Pirooznia, Jennifer Parla, Noushin Niknafs, K. Wyatt McMahon, Richard W. McCombie, Alvin Makohon-Moore, Melissa Kramer, Christine Iacobuzio-Donahue, Joseph M. Herman, Fernando S. Goes, Christopher Douville, Erica J. Childs, Michele L. Cote, Yun-Ching Chen, Kari G. Chaffee, Jennifer Axilbund, Syed Z. Ali, George Zogopoulos, Sapna Syngal, Elena Stoffel, Ann G. Schwartz, Anil K. Rustgi, Sara H. Olson, Robert C. Kurtz, Steven Gallinger, Randall Brand, Melissa L. Bondy, Gloria M. Petersen, Alexis L. Norris, Nicholas J. Roberts
Supplementary Tables S1 - S12. Supplementary Table S1. Prioritization of candidate FPC susceptibility genes by private heterozygous PTVs. Supplementary Table S2. FPC patients harboring a private PTVs ASXL1, DNMT3A, and TET2. Supplementary Table S3. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575bafdf79112f2f0bd50501c80d81de
https://doi.org/10.1158/2159-8290.22531232.v1
https://doi.org/10.1158/2159-8290.22531232.v1
Autor:
Michael Goggins, Michael Borges, Kimberly Walter, Seung-Mo Hong, Ang Li, Audrey Vincent, Margaret Griffith, Noriyuki Omura
Supplementary Figures S1-S3 and Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a59f7e104eb064d20560a4eb5b3888f
https://doi.org/10.1158/1541-7786.22519341
https://doi.org/10.1158/1541-7786.22519341
Autor:
Michael Goggins, Ralph H. Hruban, Volkan N. Adsay, Joseph Herman, Christopher Wolfgang, Alison Klein, Erica Childs, Michael Borges, Spencer Knight, Burcu Saka, Haeryoung Kim
Purpose: To determine how often loss of ataxia-telangiectasia–mutated (ATM) protein expression occurs in primary pancreatic ductal adenocarcinomas and to determine its prognostic significance.Experimental Design: The expression of ATM and TP53 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5346c329f5358ea17bfcdb491e7b8519
https://doi.org/10.1158/1078-0432.c.6522471.v1
https://doi.org/10.1158/1078-0432.c.6522471.v1
Supplementary Table S4 from Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003f86b0e6df145bcacc61d15c0eb616
https://doi.org/10.1158/1078-0432.22440988.v1
https://doi.org/10.1158/1078-0432.22440988.v1
Autor:
Michael Goggins, Ralph H. Hruban, Anne Marie Lennon, Christopher Wolfgang, Marcia I. Canto, Matthew Weiss, Meredith Pittman, Jun Yu, Masaya Suenaga, Marco Dal Molin, Tatsuo Hata
Figure S1: Coefficient of variation telomerase assay. Figure S2: Telomerase assay controls Figure S3; Serial dilution, limit of detection telomerase assay, Figure S4; Protein extraction and assay performance; Figure S5; Lack of telomerase activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625082f2de55b14698b21918eb312bef
https://doi.org/10.1158/1078-0432.22466661
https://doi.org/10.1158/1078-0432.22466661