Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Michael, Glotzer"'
Autor:
Bingying Chen, Bo-Jui Chang, Stephan Daetwyler, Felix Zhou, Shiv Sharma, Donghoon M. Lee, Amruta Nayak, Jungsik Noh, Konstantin Dubrovinski, Elizabeth H. Chen, Michael Glotzer, Reto Fiolka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Projection imaging accelerates volumetric interrogation in fluorescence microscopy, but for multi-cellular samples, the resulting images may lack contrast, as many structures and haze are summed up. Here, we demonstrate rapid projective ligh
Externí odkaz:
https://doaj.org/article/9bd5d3508f8a4bc19a3dd71e0dbb438d
Autor:
Katrina M Longhini, Michael Glotzer
Publikováno v:
eLife, Vol 11 (2022)
In the early Caenorhabditis elegans embryo, cell polarization and cytokinesis are interrelated yet distinct processes. Here, we sought to understand a poorly understood aspect of cleavage furrow positioning. Early C. elegans embryos deficient in the
Externí odkaz:
https://doaj.org/article/a10debc78ed84f8ba4c0608c8c616a10
Publikováno v:
eLife, Vol 9 (2020)
Ventral furrow formation, the first step in Drosophila gastrulation, is a well-studied example of tissue morphogenesis. Rho1 is highly active in a subset of ventral cells and is required for this morphogenetic event. However, it is unclear whether sp
Externí odkaz:
https://doaj.org/article/f064ffd212eb49e0b15b823f0ae8a035
Autor:
Wen Lu, Margot Lakonishok, Rong Liu, Neil Billington, Ashley Rich, Michael Glotzer, James R Sellers, Vladimir I Gelfand
Publikováno v:
eLife, Vol 9 (2020)
Local accumulation of oskar (osk) mRNA in the Drosophila oocyte determines the posterior pole of the future embryo. Two major cytoskeletal components, microtubules and actin filaments, together with a microtubule motor, kinesin-1, and an actin motor,
Externí odkaz:
https://doaj.org/article/da1f41b7385848a7b9f2c71e6841a8dd
Autor:
Patrick W. Oakes, Elizabeth Wagner, Christoph A. Brand, Dimitri Probst, Marco Linke, Ulrich S. Schwarz, Michael Glotzer, Margaret L. Gardel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Cellular contractility is regulated by the GTPase RhoA, but how local signals are translated to a cell-level response is not known. Here the authors show that targeted RhoA activation results in propagation of force along stress fibres and actin flow
Externí odkaz:
https://doaj.org/article/447431f6514b4d158ce8bc4408d48bfd
Autor:
Michael Glotzer, Ashley Rich
Publikováno v:
Small GTPases. 12:416-428
Epithelial folding is a common means to execute morphogenetic movements. The gastrulating Drosophila embryo offers many examples of epithelial folding events, including the ventral, cephalic, and dorsal furrows. Each of these folding events is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a993841819775363511cb45d09414dcd
https://doi.org/10.1080/21541248.2021.1926879
https://doi.org/10.1080/21541248.2021.1926879
Autor:
Angika Basant, Michael Glotzer
Publikováno v:
F1000Research, Vol 6 (2017)
Cytokinesis in metazoan cells is mediated by an actomyosin-based contractile ring that assembles in response to activation of the small GTPase RhoA. The guanine nucleotide exchange factor that activates RhoA during cytokinesis, ECT-2, is highly regul
Externí odkaz:
https://doaj.org/article/ce91ae527f7f4fa18a050f0fbe03a609
Publikováno v:
eLife, Vol 6 (2017)
Cell polarization underlies many cellular and organismal functions. The GTPase Cdc42 orchestrates polarization in many contexts. In budding yeast, polarization is associated with a focus of Cdc42•GTP which is thought to self sustain by recruiting a
Externí odkaz:
https://doaj.org/article/f91e861a34a34a5098d756bbbb11ac5d