Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael, Fejtl"'
Publikováno v:
Drug Safety. 27:763-772
Drug-induced QT interval prolongation is now a major concern in safety pharmacology. Regulatory authorities such as the US FDA and the European Medicines Agency require in vitro testing of all drug candidates against the potential risk for QT interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4328e12a8c74be6840015bbbb049c40d
https://doi.org/10.2165/00002018-200427110-00002
https://doi.org/10.2165/00002018-200427110-00002
Publikováno v:
Receptors and Channels. 9:41-48
Membrane-bound neurotransmitter receptors and ion channels are among the most numerous and important drug targets, and electrophysiological methods are the gold standard for the study of their functional properties and their response to drugs. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a08ecc81608af5f68008f83eb016e55
https://doi.org/10.3109/10606820308253
https://doi.org/10.3109/10606820308253
Autor:
Diane Decker, Karolyn F. Buttle, Michael Fejtl, Donald H. Szarowski, James N. Turner, David O. Carpenter
Publikováno v:
Microscopy and Microanalysis. 1:75-85
We have used confocal laser scanning microscopy (CLSM), high-voltage electron microscopy (HVEM), and intracellular recording techniques to study volume changes in cultured Aplysia pacemaker neurons. Hyper- and hypo-tonic artificial sea water (ASW) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ecb2016ad899eb9d1dec8c5fd8db861
https://doi.org/10.1017/s1431927695110752
https://doi.org/10.1017/s1431927695110752
Publikováno v:
Cellular and Molecular Neurobiology. 14:665-674
1. The effect of mercuric(II) chloride on kinetic parameters of carbachol-activated single chloride channels were studied in cultured neurons of the marine mollusk, Aplysia californica. 2. Single neurons of Aplysia were cultured in L-15 medium contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690325e2ce1db869e894d9adcb0b7e8e
https://doi.org/10.1007/bf02088675
https://doi.org/10.1007/bf02088675
Publikováno v:
NeuroReport. 5:2317-2320
Carbachol and acetylcholine (ACh)-activated whole-cell chloride currents were recorded in identified neurons of Aplysia californica. Application of 0.1-10 microM HgCl2 potentiated the chloride response and reduced the rate of desensitization. To inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a31c4a297a6ca2c17d749c8e28fa067
https://doi.org/10.1097/00001756-199411000-00027
https://doi.org/10.1097/00001756-199411000-00027
Publikováno v:
e-Neuroforum. 5:13-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b40ada21b7527daeb4f64faa026ba1b
https://doi.org/10.1515/nf-1999-0106
https://doi.org/10.1515/nf-1999-0106
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 403
A conventional borosilicate glass patch pipette is glued into a plastic jacket, forming the entity of a FlipTip. One or two three-channel modules of recording tip sockets are mounted on a liquid handler platform to take up FlipTips. The tip sockets a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20dd189fb84d7d17a3095347c8eee876
https://pubmed.ncbi.nlm.nih.gov/18827988
https://pubmed.ncbi.nlm.nih.gov/18827988
Publikováno v:
Neuromethods ISBN: 9781588297051
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b59591fa6078338f8c955d6d35fea86
https://doi.org/10.1007/978-1-59745-492-6_15
https://doi.org/10.1007/978-1-59745-492-6_15
Publikováno v:
Methods in Molecular Biology ISBN: 9781588296986
A conventional borosilicate glass patch pipette is glued into a plastic jacket, forming the entity of a FlipTip. One or two three-channel modules of recording tip sockets are mounted on a liquid handler platform to take up FlipTips. The tip sockets a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede6151d0fd8963e1178903d959e21c7
https://doi.org/10.1007/978-1-59745-529-9_5
https://doi.org/10.1007/978-1-59745-529-9_5
Publikováno v:
Advances in Network Electrophysiology ISBN: 9780387258577
Network activity of electrically active cells such as neurons and heart cells underlies fundamental physiological and pathophysiological functions. Despite the well-known properties of single neurons, synapses, and ion channels to exhibit long-term c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f061f8441e4edb3612a2731697f790a2
https://doi.org/10.1007/0-387-25858-2_2
https://doi.org/10.1007/0-387-25858-2_2