Zobrazeno 1 - 10
of 490
pro vyhledávání: '"Michael, Ellis"'
Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer
Autor:
Michael Ellis Williams, David Howard, Claire Donnelly, Fereshteh Izadi, Jezabel Garcia Parra, Megan Pugh, Kadie Edwards, Kerryn Lutchman-Sigh, Sadie Jones, Lavinia Margarit, Lewis Francis, R. Steven Conlan, Francesca Taraballi, Deyarina Gonzalez
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Epithelial ovarian cancer (EOC) is the deadliest gynaecological cancer with high mortality rates driven by the common development of resistance to chemotherapy. EOC frequently invades the omentum, an adipocyte-rich organ of the pe
Externí odkaz:
https://doaj.org/article/9a11cb18be754c52a8ba2bfa4bed1a0a
Autor:
Stefano Serpelloni, Michael Ellis Williams, Sergio Caserta, Shashank Sharma, Maham Rahimi, Francesca Taraballi
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11701-11717 (2024)
Externí odkaz:
https://doaj.org/article/2dafd380e67a4a029330e8e032819349
Autor:
Williams, Michael Ellis1 (AUTHOR), Howard, David1 (AUTHOR), Donnelly, Claire1 (AUTHOR), Izadi, Fereshteh1 (AUTHOR), Parra, Jezabel Garcia1 (AUTHOR), Pugh, Megan1 (AUTHOR), Edwards, Kadie1 (AUTHOR), Lutchman-Sigh, Kerryn2 (AUTHOR), Jones, Sadie3 (AUTHOR), Margarit, Lavinia1,4 (AUTHOR), Francis, Lewis1 (AUTHOR), Conlan, R. Steven1 (AUTHOR), Taraballi, Francesca5 (AUTHOR), Gonzalez, Deyarina1 (AUTHOR) d.gonzalez@swansea.ac.uk
Publikováno v:
Cell Communication & Signaling. 9/16/2024, Vol. 22 Issue 1, p1-18. 18p.
Autor:
Brian R. Berridge, Szczepan W. Baran, Vivek Kumar, Natalie Bratcher-Petersen, Michael Ellis, Chang-Ning Liu, Timothy L. Robertson
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Though the portfolio of medicines that are extending and improving the lives of patients continues to grow, drug discovery and development remains a challenging business on its best day. Safety liabilities are a significant contributor to development
Externí odkaz:
https://doaj.org/article/ad27030667f84b9e82a29fe81d79692c
Distributed storage employs replication to mask failures and improve availability. However, these systems typically exhibit a hard tradeoff between consistency and performance. Ensuring consistency introduces coordination overhead, and as a result th
Externí odkaz:
http://arxiv.org/abs/1904.08964
Publikováno v:
JMIR Mental Health, Vol 10, p e43929 (2023)
BackgroundAcceptability of digital mental health interventions is a significant predictor of treatment-seeking behavior and engagement. However, acceptability has been conceptualized and operationalized in various ways, which decreases measurement pr
Externí odkaz:
https://doaj.org/article/1befa0944893466a9569355b9348a079
Autor:
Karen L. Svenson, Stephen D. Krasinski, Michael Ellis, Nadia Rosenthal, Edison T. Liu, Kenneth H. Fasman
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 10 (2022)
Externí odkaz:
https://doaj.org/article/af83b92c2a734ff886296c5d4cdc230d
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 27, Iss , Pp 101680- (2022)
Purpose: To report clinical outcomes of a pediatric patient with unilateral reversible vision loss secondary to hypotony from repeated accidental nocturnal ocular compression from circumaural headphone wear. Observations: A 17-year-old male with path
Externí odkaz:
https://doaj.org/article/382d401eadf6402191faf8e905d251ff
Autor:
Ariadna Recasens, Sean J. Humphrey, Michael Ellis, Monira Hoque, Ramzi H. Abbassi, Brianna Chen, Mitchell Longworth, Elise J. Needham, David E. James, Terrance G. Johns, Bryan W. Day, Michael Kassiou, Pengyi Yang, Lenka Munoz
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-16 (2021)
Abstract Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our
Externí odkaz:
https://doaj.org/article/0a8dca1bb09e4683a7fb6162b88375d9
Autor:
Lucy J. Brooks, Melanie P. Clements, Jemima J. Burden, Daniela Kocher, Luca Richards, Sara Castro Devesa, Leila Zakka, Megan Woodberry, Michael Ellis, Zane Jaunmuktane, Sebastian Brandner, Gillian Morrison, Steven M. Pollard, Peter B. Dirks, Samuel Marguerat, Simona Parrinello
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glioma stem cells (GSCs) retain the ability to partially differentiate, but it is unclear how the brain microenvironment may influence this response. Here the authors show that glioblastoma cells infiltrating into the white matter acquire pre-oligode
Externí odkaz:
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae