Digital remote monitoring for screening and early detection of urinary tract infections

Autor: Alexander Capstick, Francesca Palermo, Kimberley Zakka, Nan Fletcher-Lloyd, Chloe Walsh, Tianyu Cui, Samaneh Kouchaki, Raphaella Jackson, Martin Tran, Michael Crone, Kirsten Jensen, Paul Freemont, Ravi Vaidyanathan, Magdalena Kolanko, Jessica True, Sarah Daniels, David Wingfield, CR&T Group, Ramin Nilforooshan, Payam Barnaghi

Publikováno v: npj Digital Medicine, Vol 7, Iss 1, Pp 1-7 (2024)

Abstract Urinary Tract Infections (UTIs) are one of the most prevalent bacterial infections in older adults and a significant contributor to unplanned hospital admissions in People Living with Dementia (PLWD), with early detection being crucial due t

Externí odkaz: https://doaj.org/article/b50d94c4ad314b258953606e10d2a093

Using home monitoring technology to study the effects of traumatic brain injury on older multimorbid adults: protocol for a feasibility study

Autor: Paresh Malhotra, David J Sharp, Yuchen Zhao, Michael David, David Sharp, Michael Fertleman, Lenny Naar, Sarah Daniels, Ramin Nilforooshan, Derk-Jan Dijk, Claire Norman, Greg Scott, Ian Williams, John Patterson, Neil Graham, David Wingfield, Mara Golemme, Melanie Dani, Sanara Raza, Lucia M Li, Sumit Dey, Eyal Soreq, Payam Barnaghi, Martina Del Giovane, Magdalena Kolanko, Ciro Della Monica, Helen Lai, Tong Wu, Megan E Parkinson, Danielle Wilson, Zaynab Ismail, Paul Freemont, Ravi Vaidyanathan, Tim Constandinou, Naomi Hassim, Mark Crook Rumsey, Emma Jane Mallas, Alina-Irina Serban, Alan Bannon, Shlomi Haar, Charalambos Hadjipanayi, Ghena Hammour, Bryan Hsieh, Adrien Rapeaux, Maowen Yin, Maria Lima, Maitreyee Wairagkar, Nan Fletcher-Lloyd, Hamed Haddadi, Valentinas Janeiko, Anna Joffe, Samaneh Kouchaki, Viktor Levine, Honglin Li, Amer Marzuki, Francesca Palermo, Mark Woodbridge, Alexander Capstick, Severin Skillman, Loren Cameron, Michael Crone, Kirsten Jensen, Anne Skeldon, Kevin Wells, Ullrich Bartsch, Kiran G R Kumar, Damion Lambert, Sara Mohammadi Mahvash, Thalia Rodriguez Garcia, Martin Tran, Thomas Adam, Vikki Revell, Giuseppe Atzori, Lucinda Grainger, Hana Hassanin, James Woolley, Iris Wood-Campar, Janetta Rexha, Sophie Horrocks, Brian Quan, Jessica True, Olga Balazikova, Emily Beale, Vaiva Zarombaite, Lucy Copps, Olivia Knight, Gaganpreet Bangar, Chelsea Mukonda, Jessica Hine, Luke Mallon, Anesha Patel, Ruby Lyall, Pippa Kirby, Mike Law, Andy Kenny

Publikováno v: BMJ Open, Vol 13, Iss 5 (2023)

Introduction The prevalence of traumatic brain injury (TBI) among older adults is increasing exponentially. The sequelae can be severe in older adults and interact with age-related conditions such as multimorbidity. Despite this, TBI research in olde

Externí odkaz: https://doaj.org/article/7ac3b4d583fb40b7a0a33329f530b719

On-grid purification of electron microscopy samples via a 3D-printed flow-cell

Autor: Kailash Ramlaul, Ziyi Feng, Caoimhe Canavan, Natàlia de Martín Garrido, David Carreño, Michael Crone, Kirsten E. Jensen, Bing Li, Harry Barnet, David T. Riglar, David Miller, Paul S. Freemont, Christopher H. S. Aylett

While recent advances in cryogenic electron microscopy coupled with single particle analysis have the potential to allow structure determination in a near-native state from vanishingly few individual particles, this vision has yet to be realised in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39b6c63ab850304edad0ace0fc9b8011
https://doi.org/10.1101/2023.03.17.533159

Simple, low-cost production of DNA MS2 virus-like particles as molecular diagnostic controls

Autor: Michael Crone, Paul Freemont

Suitable controls are integral for the validation and continued quality assurance of diagnostic workflows. Plasmids, DNA or in vitro transcribed RNA are often used to validate novel diagnostic workflows, however, they are poorly representative of cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c895d4fcece250ba8d99f149f7efbde
https://doi.org/10.1101/2022.09.04.506540

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Autor: Hon Ming Yip, Shiyu Cheng, Evan J. Olson, Michael Crone, Sebastian J. Maerkl

Cells cope with and adapt to ever-changing environmental conditions. Sophisticated regulatory networks allow cells to adjust to these fluctuating environments. One such archetypal system is the Saccharomyces cerevisiae Pho regulon. When external inor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df3a2ab43c738ad93b630ae10bdbbcc
https://doi.org/10.1101/2022.05.26.493535