Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Michael, Brehm"'
Autor:
Renata Stripecke, Christian Münz, Jan Jacob Schuringa, Karl‐Dimiter Bissig, Brian Soper, Terrence Meeham, Li‐Chin Yao, James P Di Santo, Michael Brehm, Estefania Rodriguez, Anja Kathrin Wege, Dominique Bonnet, Silvia Guionaud, Kristina E Howard, Scott Kitchen, Florian Klein, Kourosh Saeb‐Parsy, Johannes Sam, Amar Deep Sharma, Andreas Trumpp, Livio Trusolino, Carol Bult, Leonard Shultz
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp 1-16 (2020)
Abstract Mice xenotransplanted with human cells and/or expressing human gene products (also known as “humanized mice”) recapitulate the human evolutionary specialization and diversity of genotypic and phenotypic traits. These models can provide a
Externí odkaz:
https://doaj.org/article/0b7a5df243a34bd59c1903d19ca29593
Autor:
Phuong Nguyen, Igor Feldman, Mohammad Zafari, Ryan Phennicie, Kevin Kauffman, Dominika Nowakowska, Veronica Komoroski, Steve Sazinsky, Joe Wahle, Denise Manfra, Shantashri Vaidya, Michael Brehm, Tatiana Novobrantseva
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/b6379b7f4004491ab3e4d49d57c3f7b7
Autor:
Yetao Wang, Lawrence M Lifshitz, Noah Silverstein, Esther Mintzer, Kevin Luk, Pamela StLouis, Michael Brehm, Scot A. Wolfe, Steven Deeks, Jeremy Luban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49018c860e96a6b9cfdbe3dc2fcce53e
https://doi.org/10.15252/rc.2023978741
https://doi.org/10.15252/rc.2023978741
Autor:
Kelly Shi, Cindy Tan, Lu Bai, Jennifer Richardson, Andy Deng, Matthias Will, Michael Brehm, Dale Greiner, Leonard Shultz, Antonella Teramo, Renato Zambello, David J Feith, Thomas P. Loughran, Nenad Tomasevic
Publikováno v:
Blood. 140:2259-2260
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d9a336e62e7deef840a56b4c97c374
https://doi.org/10.1182/blood-2022-159242
https://doi.org/10.1182/blood-2022-159242
Autor:
Mengdie Wang, Christi A Wisniewski, Choua Xiong, Peter Chhoy, Hira Goel, Zhiwen Xu, Massimo Loda, Zhong Jiang, Michael Brehm, Arthur Mercurio
Publikováno v:
Cancer Immunology Research. 10:A44-A44
Prostate cancers (PC) are largely unresponsive to immune checkpoint inhibitors and there is strong evidence that PD-L1 expression itself must be inhibited to activate anti-tumor immunity. Here, we report that neuropilin-2 (NRP2), which functions as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9db11cc5fc520cf20d584fe912c8d9
https://doi.org/10.1158/2326-6074.tumimm22-a44
https://doi.org/10.1158/2326-6074.tumimm22-a44
Autor:
Igor Feldman, Tatiana Novobrantseva, Ani Nguyen, Jessica Ritter, Mohammad Zafari, Denise Manfra, Susan Low, Steve Sazinsky, Michael Brehm, Boris Klebanov
Publikováno v:
Cancer Research. 82:5602-5602
Suppressive myeloid cells in the tumor microenvironment (TME) are associated with poor survival of cancer patients and resistance to T cell checkpoint inhibitors. These myeloid cells shield cancer cells from the sentinel immune response and create a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89bb34620bf06ac69f058bbb0573e815
https://doi.org/10.1158/1538-7445.am2022-5602
https://doi.org/10.1158/1538-7445.am2022-5602
Autor:
Naema Nayyar, Mohini Singh, Magali de Sauvage, Nazanin Ijad, Ashish Dahal, Jane Chuprin, Michael Brehm, Priscilla Brastianos
Publikováno v:
Cancer Research. 82:4181-4181
While immune checkpoint inhibitors (ICI) have revolutionized treatment of advanced cancers, few of the 30% of cancer patients who develop brain metastases benefit from immunotherapy. Inhibition of CDK4/6 pathway - altered in >50% of brain metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1844c8c4edd19949fde2d66a9f0d6e63
https://doi.org/10.1158/1538-7445.am2022-4181
https://doi.org/10.1158/1538-7445.am2022-4181
Autor:
Ani Nguyen, Jessica Ritter, Mohammad Zafari, Denise Manfra, Veronica Komoroski, Brian O'Nuallain, Ryan Phennicie, Kevin Kauffman, Dominika Nowakowska, Joe Wahle, Steve Sazinsky, Michael Brehm, Igor Feldman, Tatiana Novobrantseva
Publikováno v:
Molecular Cancer Therapeutics. 20:P107-P107
Suppressive myeloid populations in the tumor microenvironment are associated with worse survival of cancer patients and low effectiveness of T cell checkpoint inhibitors. Recently, several early clinical studies have produced positive data for therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2086aa46dc29cace57f67e0a033e5d
https://doi.org/10.1158/1535-7163.targ-21-p107
https://doi.org/10.1158/1535-7163.targ-21-p107
Autor:
Naema Nayyar, Ashish Dahal, Priscilla K. Brastianos, Michael Brehm, Magali De Sauvage, Mohini Singh
Publikováno v:
Neuro-Oncology. 23:vi74-vi74
While immune checkpoint inhibitors (ICI) have revolutionized treatment of metastatic melanoma, few of the 75% of patients who develop brain metastases benefit from immunotherapy. Inhibition of CDK4/6 pathway – altered in ~90% of melanoma patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3473f87f8ef82843c18ac5f66b116e56
https://doi.org/10.1093/neuonc/noab196.285
https://doi.org/10.1093/neuonc/noab196.285
Autor:
Jens Vogel-Claussen, Michael Brehm, Kattih Badder, Christian Kühn, Johann Bauersachs, Akin Muharrem, Udo Bavendiek
Publikováno v:
International Journal of Cardiology. Heart & Vasculature
International Journal of Cardiology: Heart & Vasculature, Vol 9, Iss C, Pp 32-36 (2015)
Scipedia Open Access
Scipedia SL
International Journal of Cardiology: Heart & Vasculature, Vol 9, Iss C, Pp 32-36 (2015)
Scipedia Open Access
Scipedia SL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084bcf3dd84642487a0dd78f23374816
http://europepmc.org/articles/PMC5497280
http://europepmc.org/articles/PMC5497280