Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Michael, Brüss"'
Publikováno v:
BioTechniques, Vol 40, Iss 2, Pp 173-177 (2006)
Real-time PCR is a powerful technique for gene expression studies, which have become increasingly important in a large number of clinical and scientific fields. The significance of the obtained results strongly depends on the normalization of the dat
Externí odkaz:
https://doaj.org/article/80d74c13f08745a295ad1040eb34c484
Publikováno v:
Pharmacological Reports. 63:45-53
The aim of this study was to analyze functional properties of the naturally occurring C23S variant of the human 5-HT 2C receptor. In HEK293 cells transiently expressing the unedited forms of the variant receptor (VR) or the wild-type receptor (WTR),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b3e6f8ec2525418fcc455f21732764
https://doi.org/10.1016/s1734-1140(11)70397-8
https://doi.org/10.1016/s1734-1140(11)70397-8
Autor:
Beate Niesler, Christopher N. Connolly, Michael Brüss, Jutta Walstab, Heinz Bönisch, Dorothee Möller, Christian Hammer, Felix Lasitschka, Gudrun A. Rappold
Publikováno v:
The Journal of Biological Chemistry
Although five 5-hydroxytryptamine type 3 (5-HT3) subunits (A-E) have been cloned, knowledge on the regulation of their assembly is limited. RIC-3 has been identified as a chaperone specific for the pentameric ligand-gated nicotinic acetylcholine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96961e33268664b0912c9677d44a2d6c
https://doi.org/10.1074/jbc.m110.122838
https://doi.org/10.1074/jbc.m110.122838
Autor:
Peter Propping, Astrid Zobel, Wolfgang Maier, Rolf Fimmers, Ralf Gilsbach, Markus M. Nöthen, Susanne Höfels, Karoline Linsel, Marcella Rietschel, Michael Brüss, Manfred Göthert, Heinz Bönisch, Vera Guttenthaler, Britta Haenisch
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :1013-1016
Dysregulations of central noradrenergic and serotonergic neurotransmission have been suggested to contribute to the pathogenesis of neuropsychiatric disorders such as depression. The norepinephrine transporter (NET; SLC6A2) and the serotonin (5-HT)1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f107de992e4be068d89579ada3e702
https://doi.org/10.1002/ajmg.b.30912
https://doi.org/10.1002/ajmg.b.30912
Autor:
Arevat Kostanian, Jutta Walstab, Heinz Bönisch, Sandra Combrink, Michael Brüss, Manfred Göthert, Martin Barann
Publikováno v:
Pharmacological Reports. 61:785-797
The present study aimed at examining the function and pharmacological properties of the naturally occurring Arg344His variant of the human 5-HT(3A) receptor, identified in a schizophrenic patient. In intact human embryonic kidney (HEK) 293 cells expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83eb63e3b103496ded7109bc5cb21a6b
https://doi.org/10.1016/s1734-1140(09)70134-3
https://doi.org/10.1016/s1734-1140(09)70134-3
Autor:
Christiana Wolf, Heinz Bönisch, Michael Brüss, Ivar von Kügelgen, Manfred Göthert, Gerhard J. Molderings
Publikováno v:
Neurochemistry International. 51:476-485
The present study aimed at elucidating the molecular identity of the proposed “I 1 -imidazoline receptors”, i.e. non-adrenoceptor recognition sites via which the centrally acting imidazolines clonidine and moxonidine mediate a major part of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4784c7155959deb8347402598e077225
https://doi.org/10.1016/j.neuint.2007.04.022
https://doi.org/10.1016/j.neuint.2007.04.022
Autor:
Gerhard J. Molderings, Christian Scheurlen, Michael Brüss, Jürgen Homann, Ulrich W. Kolck, Ivar Von Kügelgen
Publikováno v:
Scandinavian Journal of Gastroenterology. 42:1045-1053
Objective. Sequencing efforts to discover mutations in the tyrosine kinase Kit related to systemic mast cell disorders have so far been focused mainly on only a few of the 21 exons of the encoding gene c-kit, thus considerably limiting the possibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e4b1a02286abb4cdd9e5e01af0df06
https://doi.org/10.1080/00365520701245744
https://doi.org/10.1080/00365520701245744
Publikováno v:
European Journal of Pharmacology. 531:54-58
([ 3 H]5-HT)-uptake and patch-clamp techniques were used to study the actions of (+) and (−) tramadol and the active metabolites of tramadol, (+) and (−) O-demethyl-tramadol on the human serotonin (5-HT) transporter and the human 5-HT 3A receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dbc8ff29c05dbe0137621a4a4fef00
https://doi.org/10.1016/j.ejphar.2005.11.054
https://doi.org/10.1016/j.ejphar.2005.11.054
Autor:
Michael Brüss, Marc G. Caron, Heinz Bönisch, Ralf Gilsbach, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka, Zofia Rogóż
Publikováno v:
Journal of Neurochemistry. 96:1111-1120
The norepinephrine transporter (NET) is responsible for the rapid removal of norepinephrine released from sympathetic neurons; this release is controlled by inhibitory alpha(2)-adrenergic receptors (alpha(2)ARs). Long-term inhibition of the NET by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a250aef45d111cdd20e727df5713325f
https://doi.org/10.1111/j.1471-4159.2005.03598.x
https://doi.org/10.1111/j.1471-4159.2005.03598.x
Publikováno v:
International Congress Series. 1283:49-54
The action of metoclopramide, a drug which is used as an antiemetic and prokinetic, on human (h)5-HT 3A receptors, stably expressed in HEK-293 cells, was studied with patch clamp and [ 3 H]-radioligand binding techniques. At clinical concentrations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4344b75061a4b3ea76a6e10ccdba090
https://doi.org/10.1016/j.ics.2005.08.006
https://doi.org/10.1016/j.ics.2005.08.006