Novel derivatives of aroylacrylic acid phenylamides as inducers of apoptosis through the ROS-mediated pathway in several cancer cell lines

Autor: Tamara Vasović, Milan Nikolić, Irena Novaković, Ilija N. Cvijetić, Maja D. Vitorović-Todorović, Tamara B. Vujatović, Snežana Bjelogrlić

Publikováno v: Journal of Molecular Structure

In the present work, the α, β-double bond of the aroylacrylic acid phenylamides was suitably modified to optimize the toxicity–antiproliferative activity ratio of the resulting compounds 1 –5 . The phenylamides were modified by Michael’s addi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a725e09ef94d88c4b0419285fb1bca04
https://cer.ihtm.bg.ac.rs/handle/123456789/4857

Design of new sensitive α,β-unsaturated carbonyl 1,8-naphtalimide fluorescent probes for thiol bioimaging

Autor: Franck Bagala, Maria Nikolantonaki, Rémi Saurel, Stéphane Guyot, Anne-Sophie Viaux, Florence Husson, Thanh Dat Nguyen, Régis D. Gougeon, Nicolas Sok, Yoann Rousselin

Publikováno v: Sensors and Actuators B: Chemical
Sensors and Actuators B: Chemical, Elsevier, 2017, 242, pp.865-871. 〈10.1016/j.snb.2016.09.171〉
Sensors and Actuators B: Chemical, Elsevier, 2017, 242, pp.865-871. ⟨10.1016/j.snb.2016.09.171⟩

International audience; We report herein an efficient synthesis of news naphtalimide-based fluorescent derivatives functionalized with an a,(3-unsaturated carbonyl group. Probes were synthesized from reaction of an amino-naphtalimide precursor with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f8719fc0227b31855b7182e6a5e821
https://doi.org/10.1016/j.snb.2016.09.171

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