Výsledky vyhledávání - "Micha P. Krahl"

Palladium(II)-Catalyzed Synthesis of the Formylcarbazole Alkaloids Murrayaline A-C, 7-Methoxymukonal, and 7-Methoxy-O-methylmukonal

Autor: Micha P. Krahl, Olga Kataeva, Anne Jäger, Ronny Hesse, Arndt W. Schmidt, Hans-Joachim Knölker

Publikováno v: European Journal of Organic Chemistry. 2014:4014-4028

We describe the synthesis of the naturally occurring 2,7-dioxygenated formylcarbazole alkaloids 7-methoxymukonal, 7-methoxy-O-methylmukonal, and the murrayalines A–C. The carbazole framework was constructed by a Buchwald–Hartwig amination and a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a59157f4f7daef5b49beab63f3646ea
https://doi.org/10.1002/ejoc.201402201

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Iron-Mediated Total Synthesis of 2,7-Dioxygenated Carbazole Alkaloids

Autor: Arndt W. Schmidt, Hans-Joachim Knölker, Micha P. Krahl, Olga Kataeva

Publikováno v: European Journal of Organic Chemistry. 2013:59-64

We describe the efficient iron-mediated total synthesis of clausine O, clausine H (clauszoline-C) and anti-HIV active 7-methoxy-O-methylmukonal and clausine K (clauszoline-J). Consecutive C–C and C–N bond formations between 3-methoxy-4-methylanil

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https://doi.org/10.1002/ejoc.201201251

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Transition Metals in Organic Synthesis, Part 87: An Efficient Palladium-Catalyzed Route to 2-Oxygenated and 2,7-Dioxygenated Carbazole Alkaloids - Total Synthesis of 2-Methoxy-3-methylcarbazole, Glycosinine, Clausine L, Mukonidine, and Clausine V

Autor: Anne Jäger, Hans-Joachim Knölker, Frank Däbritz, Micha P. Krahl, Ronny Forke

Publikováno v: Synlett. 2008:1870-1876

Optimization of the palladium(II)-catalyzed oxidative cyclization of N,N-diarylamines opens up the way to an efficient synthesis of 2-oxygenated and 2,7-dioxygenated carbazole alkaloids including 2-methoxy-3-methylcarbazole, glycosinine, clausine L,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91a45ae261d81fa7da44e0ad74dc62bc
https://doi.org/10.1055/s-2008-1078508

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Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles

Autor: Taylor A. Choi, Kethiri R. Reddy, Jan Knöll, Hans-Joachim Knölker, Scott G. Franzblau, Micha P. Krahl, Anne Jäger, Tilo Krause, Ronny Forke, Regina Czerwonka

Publikováno v: Medicinal Chemistry Research. 17:374-385

A series of carbazole derivatives with promising pharmacological properties has been prepared using either an iron-mediated or a palladium-catalyzed synthetic approach. The carbazole alkaloids carbazoquinocin C, carbazomadurin A and B, epocarbazolin

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https://doi.org/10.1007/s00044-007-9073-0

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Transition Metals in Organic Synthesis, Part 82. First Total Synthesis of Methyl 6-Methoxycarbazole-3-carboxylate, Glycomaurrol, the Anti-TB Active Micromeline, and the Furo[2,3-c]carbazole Alkaloid Eustifoline-D

Autor: Georg Schlechtingen, Micha P. Krahl, Hans-Joachim Knölker, Tilo Krause, Ronny Forke

Publikováno v: Synlett. 2007:0268-0272

The palladium(0)-catalyzed amination followed by palladium(II)-catalyzed oxidative cyclization of the resulting diaryl-amine provides a short route to a series of 6-oxygenated carbazole alkaloids: glycozoline, 3-formyl-6-methoxycarbazole, methyl 6-me

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https://doi.org/10.1055/s-2007-967984

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ChemInform Abstract: Transition Metals in Organic Synthesis. Part 104. Iron-Mediated Total Synthesis of Furoclausine-A

Autor: Arndt W. Schmidt, Micha P. Krahl, Hans‐Joachim Knoelker

Publikováno v: ChemInform. 44

Title compound (I) is synthesized starting from 2-methyl-5-nitrophenol convergent in 7 steps and 7% overall yield using iron-mediated coupling reactions.

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https://doi.org/10.1002/chin.201317201

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First total synthesis of the biscarbazole alkaloid oxydimurrayafoline

Autor: Carsten Börger, Margit Gruner, Olga Kataeva, Hans-Joachim Knölker, Micha P. Krahl

Publikováno v: Organic & biomolecular chemistry 2012;10:5189–5193, ISSN: 1477-0520

We report the first total synthesis of oxydimurrayafoline via nucleophilic substitution at the benzylic position at C-3 of the carbazole framework. Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. N

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https://pubmed.ncbi.nlm.nih.gov/22689142

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