Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Micha E. Spira"'
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Developing novel neuroprobes that enable parallel multisite, long-term intracellular recording and stimulation of neurons in freely behaving animals is a neuroscientist’s dream. When fulfilled, it is expected to significantly enhance brain research
Externí odkaz:
https://doaj.org/article/232c27a6262e42aba20f085af3793439
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Despite increasing use of in vivo multielectrode array (MEA) implants for basic research and medical applications, the critical structural interfaces formed between the implants and the brain parenchyma, remain elusive. Prevailing view assumes that f
Externí odkaz:
https://doaj.org/article/599368f3243b4ab285e588ef4deeb0f2
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Inflammatory encapsulation of implanted cortical-neuro-probes [the foreign body response (FBR)] severely limits their use in basic brain research and in clinical applications. A better understanding of the inflammatory FBR is needed to effectively mi
Externí odkaz:
https://doaj.org/article/9918803fa21b49fc8add619f0ed354dd
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 569 (2022)
Microglia play pivotal roles in central nervous system development, homeostasis, responses to trauma, and neurodegenerative and neuropsychiatric disorders with significant sex-bias in their symptoms and prevalence. Survival of the microglia in adult
Externí odkaz:
https://doaj.org/article/9be1aa0c3570408d97099d657c14736c
Autor:
Shun-Ho Huang, Nava Shmoel, Maciej M. Jankowski, Hadas Erez, Aviv Sharon, Wesal Abu-Salah, Israel Nelken, Aryeh Weiss, Micha E. Spira
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The deterioration of field potential (FP) recording quality and yield by in vivo multielectrode arrays (MEA) within days to weeks of implantation severely limits progress in basic and applied brain research. The prevailing hypothesis is that implanta
Externí odkaz:
https://doaj.org/article/eabe022436af40448d12429236eef760
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Multielectrode arrays (MEA) are used extensively for basic and applied electrophysiological research of neuronal- and cardiomyocyte-networks. Whereas immense progress has been made in realizing sophisticated MEA platforms of thousands of addressable,
Externí odkaz:
https://doaj.org/article/b88123419dee48a6ba7056acb0759378
Autor:
Or A. Shemesh, Micha E. Spira
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 163-175 (2011)
Through the use of live confocal imaging, electron microscopy, and the novel cell biological platform of cultured Aplysia neurons we show that unfolding of the hallmark cell pathologies induced by mutant-human-tau (mt-human-tau) expression is rescued
Externí odkaz:
https://doaj.org/article/f2e14ad2963249b888349611268d87ba
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Behavioral and electrophysiological studies of Alzheimer’s disease (AD) and other tauopathies have revealed that the onset of cognitive decline correlates better with synaptic dysfunctions than with hallmark pathologies such as extracellular amyloi
Externí odkaz:
https://doaj.org/article/8eed0f0ccfff4f6faa7407f51b3a9a7e
Autor:
Guy eMalkinson, Micha E. Spira
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Much of what we know about the mechanisms underlying Homosynaptic Depression (HSD) and heterosynaptic facilitation is based on intracellular recordings of integrated postsynaptic potentials. This methodological approach views the presynaptic apparatu
Externí odkaz:
https://doaj.org/article/03d8796b99644da1820e5fe79e186673
Autor:
Milos Nesladek, Micha E. Spira
Publikováno v:
Nature Photonics. 16:675-677
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a0bdf7889678c778610e138acd72128
https://doi.org/10.1038/s41566-022-01075-y
https://doi.org/10.1038/s41566-022-01075-y