Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Michał Skrzycki"'
Autor:
Giuseppina Sanna, Silvia Madeddu, Gabriele Giliberti, Sandra Piras, Marta Struga, Małgorzata Wrzosek, Grażyna Kubiak-Tomaszewska, Anna E. Koziol, Oleksandra Savchenko, Tadeusz Lis, Joanna Stefanska, Piotr Tomaszewski, Michał Skrzycki, Daniel Szulczyk
Publikováno v:
Molecules, Vol 23, Iss 10, p 2554 (2018)
A series of 2-(1H-indol-3-yl)ethylthiourea derivatives were prepared by condensation of 2-(1H-indol-3-yl)ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media. The structures of the newly synthesized compounds were confirmed by spe
Externí odkaz:
https://doaj.org/article/ae9fbd4b63d44c45a4b43897d33c50d0
Autor:
Michał Skrzycki
Publikováno v:
Open Life Sciences, Vol 16, Iss 1, Pp 1225-1239 (2021)
Open Life Sciences
Open Life Sciences
This long-term research was designed to evaluate whether superoxide dismutase (SOD) isoenzymes participate in the development of human gastrointestinal neoplasms and the potential influence of the sigma1 receptor (Sig1R) on the regulation of SOD gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bf6c991d04addbe1d171cd17aa6c70
https://doaj.org/article/c11c3b7f13204115b98f09947c5b75dc
https://doaj.org/article/c11c3b7f13204115b98f09947c5b75dc
Autor:
Michał Skrzycki, Beata Kaźmierczak
Publikováno v:
Journal of receptor and signal transduction research. 40(3)
This review describes the very specific role of Sigma1 receptor in different types of muscle cells. Sigma1 receptor is a transmembrane protein residing in such structures like MAM. It has chaperoning activity supporting function of many proteins, par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfefe91f388aaea6d829446cdfe905e
https://pubmed.ncbi.nlm.nih.gov/32054378
https://pubmed.ncbi.nlm.nih.gov/32054378
Autor:
Grażyna Kubiak-Tomaszewska, Marta Struga, Oleksandra Savchenko, Joanna Stefańska, Silvia Madeddu, Michał Skrzycki, Anna E. Koziol, Tadeusz Lis, Małgorzata Wrzosek, Daniel Szulczyk, Giuseppina Sanna, Gabriele Giliberti, Piotr Tomaszewski, Sandra Piras
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 10
Molecules, Vol 23, Iss 10, p 2554 (2018)
Molecules
Volume 23
Issue 10
Molecules, Vol 23, Iss 10, p 2554 (2018)
A series of 2-(1H-indol-3-yl)ethylthiourea derivatives were prepared by condensation of 2-(1H-indol-3-yl)ethanamine with appropriate aryl/alkylisothiocyanates in anhydrous media. The structures of the newly synthesized compounds were confirmed by spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741a9790cded1fb621f5aae9085e7f8c
https://pubmed.ncbi.nlm.nih.gov/30301264
https://pubmed.ncbi.nlm.nih.gov/30301264
Autor:
Hanna Czeczot, Michał Skrzycki
Publikováno v:
Current Protein & Peptide Science. 15:798-811
The Sigma Receptor 1 (sig-1R) is a protein present in numerous normal tissues, such as brain, retina, lens, liver, lung, heart, but also in many tumor lines. Its amino acid sequence is homologous to fungal C-8,7 sterol isomerase, but it has no known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e4665b5432a6bff5e467536740e731
https://doi.org/10.2174/138920371508141128151324
https://doi.org/10.2174/138920371508141128151324
Autor:
Michał Skrzycki, Dagmara Otto-Ślusarczyk, Magdalena Mielczarek-Puta, Wojciech Graboń, Hanna Czeczot
Publikováno v:
Journal of receptor and signal transduction research. 37(3)
Tumor cells due to distance from capillary vessels exist in different oxygenation conditions (anoxia, hypoxia, normoxia). Changes in cell oxygenation lead to reactive oxygen species production and oxidative stress. Sigma 1 receptor (Sig1R) is postula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54401bda89060c847cf8c60b3624b4b
https://pubmed.ncbi.nlm.nih.gov/27829319
https://pubmed.ncbi.nlm.nih.gov/27829319
Autor:
Michał Skrzycki, Monika Majewska, Rusłan Sałamatin, J. Twarowska, B. Grytner-Ziecina, Małgorzata Podsiad, Hanna Czeczot
Publikováno v:
Helminthologia, Vol 49, Iss 4, Pp 233-240 (2012)
The aim of this study was to evaluate changes in the enzymatic antioxidant system in rat small intestine caused by invasion of tapeworms Hymenolepis diminuta. The study material consisted of samples of the rats small intestine after short- (1.5-month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f1de37431a4e2e46113b755560bf5b
https://doi.org/10.2478/s11687-012-0044-8
https://doi.org/10.2478/s11687-012-0044-8
Autor:
Hanna Czeczot, Michał Skrzycki, Rusłan Sałamatin, B. Grytner-Ziecina, Małgorzata Podsiad, Monika Majewska
Publikováno v:
Open Life Sciences, Vol 7, Iss 6, Pp 987-995 (2012)
Background The aim of the present paper was to describe the enzymatic antioxidant system in Hymenolepis diminuta collected from rats exposed to chronic cestode invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198d002319c4603cac5b249c5beee314
https://doi.org/10.2478/s11535-012-0087-3
https://doi.org/10.2478/s11535-012-0087-3
Publikováno v:
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 39(233)
Superoxide oxidase (SOD) is a key antioxidant enzyme protecting cells against oxidative stress, which might induce cancerogenesis. In tumor cells SOD influences the level of the reactive oxygen species (ROS) allowing for survival and proliferation. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f021b262331ebaa85a3457d50f7d5c4
https://pubmed.ncbi.nlm.nih.gov/26637092
https://pubmed.ncbi.nlm.nih.gov/26637092
Autor:
Michał Skrzycki, Maria Szumiło, Dagmara Kurpios-Piec, Iwonna Rahden-Staroń, Emilia Grosicka-Maciąg, Tomasz Grzela, Hanna Czeczot
Publikováno v:
Toxicology and Applied Pharmacology. 248:210-216
This work investigated the effect of N-acetyl-L-cysteine (NAC) on disulfiram (DSF) induced oxidative stress in Chinese hamster fibroblast cells (V79). An increase in oxidative stress induced by DSF was observed up to a 200 μM concentration. It was e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a701ff372272aeba1c06e14caec12c
https://doi.org/10.1016/j.taap.2010.08.004
https://doi.org/10.1016/j.taap.2010.08.004