Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Michał Panek"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chronic inflammatory diseases of the lung are some of the leading causes of mortality and significant morbidity worldwide. Despite the tremendous burden these conditions put on global healthcare, treatment options for most of these diseases remain sc
Externí odkaz:
https://doaj.org/article/893adde37459473b8f6ff92936ef22a0
Monoclonal antibodies in the management of asthma: Dead ends, current status and future perspectives
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with moderate-to-severe asthma may now be treated using a variety of monoclonal antibodies that target key inflammatory cytokines involved in disease pathogenesis. Existing clinical data on anti-IgE, anti-IL-5 and other immunological pathway
Externí odkaz:
https://doaj.org/article/3817e538d1dc4d758cdb30731e8a498e
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTGF-β and its receptors play a crucial role in asthma pathogenesis and bronchial remodeling in the course of the disease. TGF-β1, TGF-β2, and TGF-β3 isoforms are responsible for chronic inflammation, bronchial hyperreactivity, myofibr
Externí odkaz:
https://doaj.org/article/fa54ec33dc054f0b816f26e993509b89
Publikováno v:
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Background Treatment adherence greatly influences the clinical outcomes in various fields of medicine, including management of asthma and COPD. With the recent implementation of a nationwide e-Health solutions in Poland, new and unique oppor
Externí odkaz:
https://doaj.org/article/82b36cd196ca4094b68dc8229b169b1f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Asthma is a chronic and heterogenic respiratory tract disorder with a high global prevalence. The underlying chronic inflammatory process and airway remodeling (AR) contribute to the symptomatology of the disease. The most severely ill asthma patient
Externí odkaz:
https://doaj.org/article/cdaf40d47e164ed6befa8626819195e7
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundIn allergic conditions such as allergic rhinitis and urticaria, orally administered H1-antihistamines belong to first-line therapy and therefore, are widely prescribed. Due to the frequent, and often chronic, course of allergic diseases, ad
Externí odkaz:
https://doaj.org/article/7d070adf3ee549cc994b6ead9e4aa553
Autor:
Grzegorz Kardas, Agnieszka Daszyńska-Kardas, Mateusz Marynowski, Oliwia Brząkalska, Piotr Kuna, Michał Panek
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Asthma is a chronic and heterogenic disease of the respiratory system, one of the most common lung diseases worldwide. The underlying pathologies, which are chronic inflammatory process and airway remodeling (AR), are mediated by numerous cells and c
Externí odkaz:
https://doaj.org/article/1eed156cfae940a58abd7e518893efda
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Interleukin 33 (IL-33) is an alarmin cytokine from the IL-1 family. IL-33 is localized in the nucleus and acts there as a gene regulator. Following injury, stress or cell death, it is released from the nucleus, and exerts its pro-inflammatory biologi
Externí odkaz:
https://doaj.org/article/b3ad88c35bc6469b8938e123929756df
Publikováno v:
Advances in Respiratory Medicine; Volume 90; Issue 3; Pages: 211-218
Introduction: Asthma is characterized by persistent inflammation, airway hypersensitivity and remodelling. Bone Morphogenetic Proteins belong to the Transforming Growth Factor Superfamily and have a similar signalling transduction pathway and common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f7ad78dfbd9a88b02a54b1a37e584e
https://doi.org/10.5603/arm.87955
https://doi.org/10.5603/arm.87955
Publikováno v:
COVID. 2:599-620
The COVID-19 pandemic continues to cause tremendous loss of life and put massive strain on the functioning of societies worldwide. Despite the cataclysmic proportions of this viral outbreak, as of yet, no effective curative treatment is available. CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::698b01b43fbf703b6aee785871eec34a
https://doi.org/10.3390/covid2050045
https://doi.org/10.3390/covid2050045