Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michał Śmiga"'
Autor:
Michał Śmiga, Teresa Olczak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionPorphyromonas gingivalis and Porphyromonas endodontalis belong to the Bacteroidota phylum. Both species inhabit the oral cavity and can be associated with periodontal diseases. To survive, they must uptake heme from the host as an iron an
Externí odkaz:
https://doaj.org/article/a9ba7f6d81fb4b74bf98d7d491b5a94a
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTPorphyromonas gingivalis strains exhibit different phenotypes in vitro, different virulence potential in animal models, and different associations with human diseases, with strains classified as virulent/more virulent (e.g., A7436 and W83) or
Externí odkaz:
https://doaj.org/article/473cfd776aa84558899d3fa9e251c3a1
Autor:
Michał Śmiga, Klaudia Siemińska, Soraya C. Trindade, Isaac S. Gomes-Filho, Ellen K. Nobre dos Santos, Teresa Olczak
Publikováno v:
Journal of Oral Microbiology, Vol 15, Iss 1 (2023)
ABSTRACTAims Hemophore-like proteins sequester heme from host hemoproteins. We aimed to determine whether the host immune system can recognize not only Porphyromonas gingivalis HmuY but also its homologs expressed by other periodontopathogens, and ho
Externí odkaz:
https://doaj.org/article/f407d4834c1c4156996b698e107db899
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-16 (2019)
Abstract Background Porphyromonas gingivalis is considered a keystone pathogen responsible for chronic periodontitis. Although several virulence factors produced by this bacterium are quite well characterized, very little is known about regulatory me
Externí odkaz:
https://doaj.org/article/75c18a6e2187411b9b919b8f03d50bcf
Autor:
Michał Śmiga, John W. Smalley, Paulina Ślęzak, Jason L. Brown, Klaudia Siemińska, Rosalind E. Jenkins, Edwin A. Yates, Teresa Olczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 12084 (2021)
The non-enzymatic addition of glucose (glycation) to circulatory and tissue proteins is a ubiquitous pathophysiological consequence of hyperglycemia in diabetes. Given the high incidence of periodontitis and diabetes and the emerging link between the
Externí odkaz:
https://doaj.org/article/d0c6fa6669a445a9babe3ca49a032b35
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Porphyromonas gingivalis, a keystone pathogen of chronic periodontitis, uses ferric uptake regulator homolog (PgFur) to regulate production of virulence factors. This study aimed to characterize PgFur protein in regard to its structure-function relat
Externí odkaz:
https://doaj.org/article/b6c6edb995da4d0daaa10ac9acf00fff
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2237 (2021)
Human oral and gut microbiomes are crucial for maintenance of homeostasis in the human body. Porphyromonas gingivalis, the key etiologic agent of chronic periodontitis, can cause dysbiosis in the mouth and gut, which results in local and systemic inf
Externí odkaz:
https://doaj.org/article/c5a06bd9c42d43eb94b390e209c33d70
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4150 (2020)
The oral cavity of healthy individuals is inhabited by commensals, with species of Streptococcus being the most abundant and prevalent in sites not affected by periodontal diseases. The development of chronic periodontitis is linked with the environm
Externí odkaz:
https://doaj.org/article/596abda348c841bd83e058df6387cbb4
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117508 (2015)
Given the emerging evidence of an association between periodontal infections and systemic conditions, the search for specific methods to detect the presence of P. gingivalis, a principal etiologic agent in chronic periodontitis, is of high importance
Externí odkaz:
https://doaj.org/article/2ad57bdcf1df4e9384ff473032303bcb
Autor:
Svetlana V. Antonyuk, Klaudia Siemińska, Michał Śmiga, Richard W. Strange, Mateusz Wagner, Katie J. Barnett, Teresa Olczak
Publikováno v:
The FASEB Journal. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9e9daf7a2a5665a1de596ef16c2261
https://doi.org/10.1096/fj.202300366r
https://doi.org/10.1096/fj.202300366r