Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michaël Doré"'
Autor:
Upendra Argikar, Markus Blatter, Dallas Bednarczyk, Zhuoliang Chen, Young Shin Cho, Michaël Doré, Jennifer L. Dumouchel, Samuel Ho, Klemens Hoegenauer, Toshio Kawanami, Simon Mathieu, Erik Meredith, Henrik Möbitz, Stephen K. Murphy, Saravanan Parthasarathy, Carole Pissot Soldermann, Jobette Santos, Serena Silver, Suzanne Skolnik, Aleksandar Stojanovic
Publikováno v:
Journal of medicinal chemistry. 65(18)
An imidazolone → triazolone replacement addressed the limited passive permeability of a series of protein arginine methyl transferase 5 (PRMT5) inhibitors. This increase in passive permeability was unexpected given the increase in the hydrogen bond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1191a9529fb31bd9232e1a139ca91e82
https://pubmed.ncbi.nlm.nih.gov/36069672
https://pubmed.ncbi.nlm.nih.gov/36069672
Autor:
Michaël Doré, Robert A. Singer
Publikováno v:
Organic Process Research & Development. 12:1261-1264
A practical method for coupling nitropyridones (1) with primary amines by treatment with hexamethyldisilazane has been developed, avoiding the use of hazardous reagents such as POCl3. The activation of the pyridone by a nitro group is necessary for e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab70c6efabb4ae97daaecf8311fa4cc9
https://doi.org/10.1021/op800201u
https://doi.org/10.1021/op800201u
Publikováno v:
Tetrahedron Letters. 47:3727-3731
A new family of pyrazole and bi-pyrazole phosphine ligands are reported that perform efficiently in the Pd-catalyzed amination reaction. Of the ligands screened, ligand 1 emerged as the most compatible for couplings involving both primary and seconda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7868786a9484e4b82a6b882288378007
https://doi.org/10.1016/j.tetlet.2006.03.132
https://doi.org/10.1016/j.tetlet.2006.03.132
Publikováno v:
ChemInform. 41
This new method allows formation of a number of indolizidine derivatives with high diastereoselectivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a1c4f1a5d748ae69c9a207dae24cf2
https://doi.org/10.1002/chin.201033153
https://doi.org/10.1002/chin.201033153
Publikováno v:
Organic letters. 12(7)
Although cycloadditions of azomethine ylides usually give mixtures of endo/exo adducts, we successfully tuned the mechanistic path of a new reaction cascade to afford substituted pyrrolidines in high yields and diastereomeric purity. This was achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf7f6a5a2ddedd2c0c0f5cb290012ef
https://pubmed.ncbi.nlm.nih.gov/20192221
https://pubmed.ncbi.nlm.nih.gov/20192221
Autor:
Robert A. Singer, Michaël Doré
Publikováno v:
Organic Process Research & Development; Nov2008, Vol. 12 Issue 6, p1261-1264, 4p
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7940 (2009)
Food waste contributes to excess consumption of freshwater and fossil fuels which, along with methane and CO(2) emissions from decomposing food, impacts global climate change. Here, we calculate the energy content of nationwide food waste from the di
Externí odkaz:
https://doaj.org/article/a1d70eb679bf4fbb8f5625993434538b
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