Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Micha, Hersch"'
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Over the past decade, experimental procedures such as metabolic labeling for determining RNA turnover rates at the transcriptome-wide scale have been widely adopted and are now turning to single cell measurements. Several computat
Externí odkaz:
https://doaj.org/article/a6b7b50782984eb5854d9d4e0d47434c
Autor:
Roie Cohen, Liat Amir-Zilberstein, Micha Hersch, Shiran Woland, Olga Loza, Shahar Taiber, Fumio Matsuzaki, Sven Bergmann, Karen B. Avraham, David Sprinzak
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The periodic organization of cells is typically associated with mechanisms based on intercellular signaling such as lateral inhibition and Turing patterning. Here the authors show that hair cells in the inner ear rearrange gradually into a checkerboa
Externí odkaz:
https://doaj.org/article/953a8cdf5ac942b88ac0bd29afb3bdd8
Autor:
Amiran Keshelava, Gonzalo P. Solis, Micha Hersch, Alexey Koval, Mikhail Kryuchkov, Sven Bergmann, Vladimir L. Katanaev
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
G protein-coupled receptors (GPCRs) activate intracellular signalling pathways upon extracellular stimulation. Here authors record single cell responses of GPCR signalling which allows the direct estimation of its channel capacity for each cell along
Externí odkaz:
https://doaj.org/article/e2b10c70e16e40f196b3c188a5647db1
Autor:
Micha Hersch, Olivier Hachet, Sascha Dalessi, Pranav Ullal, Payal Bhatia, Sven Bergmann, Sophie G Martin
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 7, Pp 1-7 (2015)
Abstract Concentration gradients provide spatial information for tissue patterning and cell organization, and their robustness under natural fluctuations is an evolutionary advantage. In rod‐shaped Schizosaccharomyces pombe cells, the DYRK‐family
Externí odkaz:
https://doaj.org/article/0eb6ea628170416a8c193e52ffa7fa05
Publikováno v:
BMC Bioinformatics. 23
Background Over the past decade, experimental procedures such as metabolic labeling for determining RNA turnover rates at the transcriptome-wide scale have been widely adopted and are now turning to single cell measurements. Several computational met
Autor:
Stela McLachlan, Claudia Giambartolomei, Jon White, Pimphen Charoen, Andrew Wong, Chris Finan, Jorgen Engmann, Tina Shah, Micha Hersch, Clara Podmore, Alana Cavadino, Barbara J Jefferis, Caroline E Dale, Elina Hypponen, Richard W Morris, Juan P Casas, Meena Kumari, Yoav Ben-Shlomo, Tom R Gaunt, Fotios Drenos, Claudia Langenberg, Diana Kuh, Mika Kivimaki, Rico Rueedi, Gerard Waeber, Aroon D Hingorani, Jacqueline F Price, Ann P Walker, UCLEB Consortium
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156914 (2016)
Red blood cell (RBC) traits are routinely measured in clinical practice as important markers of health. Deviations from the physiological ranges are usually a sign of disease, although variation between healthy individuals also occurs, at least partl
Externí odkaz:
https://doaj.org/article/9b6fffd77c76403c95409e3bebf988d5
Autor:
Karen B. Avraham, Shiran Woland, Micha Hersch, Sven Bergmann, Olga Loza, Shahar Taiber, Roie Cohen, David Sprinzak, Liat Amir-Zilberstein, Fumio Matsuzaki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Periodic organization of cells is required for the function of many organs and tissues. The development of such periodic patterns is typically associated with mechanisms based on intercellular signaling such as lateral inhibition and Turing patternin
Autor:
Micha Hersch, Bastian Peter, Hyun Min Kang, Fanny Schüpfer, Hugues Abriel, Thierry Pedrazzini, Eleazar Eskin, Jacques S. Beckmann, Sven Bergmann, Fabienne Maurer
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/680d63122f53464d8c1d5ebb51e452a6
Autor:
Micha Hersch, Bastian Peter, Hyun Min Kang, Fanny Schüpfer, Hugues Abriel, Thierry Pedrazzini, Eleazar Eskin, Jacques S Beckmann, Sven Bergmann, Fabienne Maurer
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41032 (2012)
β-blockers and β-agonists are primarily used to treat cardiovascular diseases. Inter-individual variability in response to both drug classes is well recognized, yet the identity and relative contribution of the genetic players involved are poorly u
Externí odkaz:
https://doaj.org/article/2e240413ba254489ac98886f32c83757
Autor:
Alexey Koval, Sven Bergmann, Amiran Keshelava, Vladimir L. Katanaev, Mikhail Kryuchkov, Gonzalo P. Solis, Micha Hersch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Nature Communications, Vol. 9, No 1 (2018) P. 876
Nature Communications
Nature communications, vol. 9, no. 1, pp. 876
Nature Communications, Vol. 9, No 1 (2018) P. 876
Nature Communications
Nature communications, vol. 9, no. 1, pp. 876
G protein-coupled receptors (GPCRs) constitute a large family of receptors that activate intracellular signaling pathways upon detecting specific extracellular ligands. While many aspects of GPCR signaling have been uncovered through decades of studi