Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michèle Pfister"'
Autor:
Georges Dedoussis, Michèle Pfister, Jean-Brice Marteau, Anastasia Samara, Sophie Visvikis-Siest
Publikováno v:
Personalized medicine. 6(3)
Aims: The gene expression of 182 cardiovascular candidate genes was measured in high quality groups of individuals (n = 20) by microarrays to determine whether a subset of genes would discriminate obese and hypertensive individuals, in spite of the e
Influence of Pre-analytical Variables on VEGF Gene Expression and Circulating Protein Concentrations
Autor:
Marie-Noëlle Ungeheuer, Catherine Ottone, Celine Chapel, Gwenaelle Gaillard, David Meyronet, Mohsen Azimi-Nezhad, Fay Betsou, Christine Masson, Michèle Pfister, Sophie Visvikis Siest, Corinne Perrin, Eric Tabone, Daniel Lambert
Publikováno v:
Biopreservation and Biobanking. 10:454-461
The extended role of vascular endothelial growth factor (VEGF) in human pathophysiology led us to evaluate pre-analytical parameters possibly influencing its levels in peripheral blood and tissues. The effects on VEGF protein levels and mRNA expressi
Autor:
Ci Song, Anita L. DeStefano, John Victor Lamont, Ndeye-Coumba Ndiaye, Radwan Safa, Seung Hoan Choi, Ramachandran S. Vasan, Michèle Pfister, Jean-Brice Marteau, Lisa M. Sullivan, Mohammad Azimi Nezhad, Qiong Yang, Stéphanie Debette, Vanessa Xanthakis, Erik Ingelsson, Peter Fitzgerald, Sudha Seshadri, Douglas B. Sawyer, Holly M. Smith, Ming-Huen Chen, Sophie Visvikis-Siest, Lars Lind, Gérard Siest
Publikováno v:
Circulation Research. 109:554-563
Rationale: Vascular endothelial growth factor (VEGF) affects angiogenesis, atherosclerosis, and cancer. Although the heritability of circulating VEGF levels is high, little is known about its genetic underpinnings. Objective: Our aim was to identify
Autor:
George Dedoussis, Alexandra Kapiri, Dimitris Dimitriadis, Gérard Siest, Daniel Lambert, Anastasia Samara, Michèle Pfister, Sophie Visvikis-Siest
Publikováno v:
European Journal of Clinical Investigation. 40:388-392
Eur J Clin Invest 2010; 40 (5): 388–392 Abstract Background Adipose tissue secrets several adipokines that have been proposed to be enrolled in many inflammatory pathways. Our aim was to investigate the adipokine expression in adipose tissue and pe
Autor:
Anastasia Samara, George Dedoussis, Daniel Lambert, Michèle Pfister, Nick Kalogeropoulos, Alexandra Kapiri, Gérard Siest, Sophie Visvikis-Siest, Dimitris Dimitriadis
Publikováno v:
Clinica Chimica Acta. 410:85-89
Objective Adipose tissue contributes in energy, lipid homeostasis and inflammation, through the adipokines it releases. Our aim was to study the associations between adipose tissue (AT) fatty acid content, adipokines' expression in AT and PBMCs and B
Autor:
Stefan Blankenberg, Daniel Lambert, Sophie Visvikis-Siest, Hamanou Benachour, Peter Fitzgerald, Michèle Pfister, Laurence Tiret, John Victor Lamont, Mohamed Zaiou, Bernard Herbeth, Gérard Siest
Publikováno v:
Pharmacogenomics. 10:951-959
Aims: The human formyl peptide receptor (FPR) is a G protein-coupled chemoattractant receptor that is thought to mediate inflammatory responses. The FPR1 gene is highly polymorphic. In a recent study, the FPR1 c.32C>T SNP, resulting in the amino-acid
Autor:
Jean-Brice Marteau, Sophie Visvikis-Siest, Elise Jeannesson, Anastasia Samara, Gérard Siest, Bérangère Marie, Michèle Pfister
Publikováno v:
Drug Metabolism and Disposition. 36:182-189
We aimed to measure simultaneously the expression of drug-metabolizing enzymes (DME) and transcription factors (TF) with high importance in cardiovascular physiopathology in lymphocytes from healthy subjects. RNA was isolated from peripheral blood mo
Publikováno v:
The Pharmacogenomics Journal. 5:271-275
This study was designed in order to investigate the influence of the genetic polymorphism of CYP2A6 on the amount of smoking. In all, 463 French adults included in the Stanislas cohort were studied and underwent two examinations at 5 years distance (
Autor:
Brigitte Leininger-Muller, Peter Passmore, Aline Hoy, Jean Marie Serot, Sophie Visvikis, Michèle Pfister, Bernard Herbeth, Luis Massana, Marina Stavljenic-Rukavina, Gérard Siest
Publikováno v:
Neuroscience Letters. 349:95-98
Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Epidemiological and molecular genetic studies have shown the existence of several genes associated with increased risk of AD, the major genetic susceptibility locus coding
Autor:
F Barbé, Jean Pierre Nicolas, Abalo Chango, Jean-Claude Guilland, J P Christidès, K Rabhi, F Boisson, Serge Hercberg, Michèle Pfister, Marie-Odile Perrin, Pilar Galan, G. Potier De Courcy
Publikováno v:
British Journal of Nutrition. 84:891-896
The 677cytosine (c)→thymine(T) mutation identified in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene has been frequently associated with an elevated plasma homocysteine concentration. The aim of the present study was to determine the imp