Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Michèle Orain"'
Autor:
Romain Villot, Audrey Poirier, Inan Bakan, Karine Boulay, Erlinda Fernández, Romain Devillers, Luciano Gama-Braga, Laura Tribouillard, Andréanne Gagné, Éma Duchesne, Danielle Caron, Jean-Sébastien Bérubé, Jean-Christophe Bérubé, Yan Coulombe, Michèle Orain, Yves Gélinas, Stéphane Gobeil, Yohan Bossé, Jean-Yves Masson, Sabine Elowe, Steve Bilodeau, Venkata Manem, Philippe Joubert, Frédérick A. Mallette, Mathieu Laplante
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
KEY FINDINGS ZNF768 is phosphorylated and degraded upon RAS activation ZNF768 depletion impairs proliferation and causes cellular senescence ZNF768 binds and represses p53 and its overexpression suffices to bypass senescence Elevated ZNF768 levels in
Externí odkaz:
https://doaj.org/article/8280dad19e4949b787cc212a7dfd3068
Autor:
Yohan Bossé, Andréanne Gagné, Wajd A. Althakfi, Michèle Orain, Christian Couture, Sylvain Trahan, Sylvain Pagé, David Joubert, Pierre O. Fiset, Patrice Desmeules, Philippe Joubert
Publikováno v:
American Journal of Surgical Pathology. 47:686-693
Autor:
Olga Sazonova, MD, MSc, Venkata Manem, MSc, PhD, Chloé Béland, MD, Marc-André Hamel, MD, Yves Lacasse, MD, Marie-Hélène Lévesque, MD, Michèle Orain, MT, David Joubert, MSc, PhD, Steeve Provencher, MD, David Simonyan, MSc, Philippe Joubert, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 4, Pp 100078- (2020)
Introduction: Diffuse idiopathic pulmonary neuroendocrine hyperplasia (DIPNECH) is a rare condition that is likely underdiagnosed owing to the lack of established and validated diagnostic criteria. These clinical guidelines are empirical and created
Externí odkaz:
https://doaj.org/article/1f041503452945db88b735d133be041a
Autor:
Andrée-Anne Grosset, Frédérick Dallaire, Tien Nguyen, Mirela Birlea, Jahg Wong, François Daoust, Noémi Roy, André Kougioumoutzakis, Feryel Azzi, Kelly Aubertin, Samuel Kadoury, Mathieu Latour, Roula Albadine, Susan Prendeville, Paul Boutros, Michael Fraser, Rob G Bristow, Theodorus van der Kwast, Michèle Orain, Hervé Brisson, Nazim Benzerdjeb, Hélène Hovington, Alain Bergeron, Yves Fradet, Bernard Têtu, Fred Saad, Frédéric Leblond, Dominique Trudel
Publikováno v:
PLoS Medicine, Vol 17, Iss 8, p e1003281 (2020)
BACKGROUND:Prostate cancer (PC) is the most frequently diagnosed cancer in North American men. Pathologists are in critical need of accurate biomarkers to characterize PC, particularly to confirm the presence of intraductal carcinoma of the prostate
Externí odkaz:
https://doaj.org/article/8fcceac90c674478ae01e4c367277d85
Autor:
Andréanne Gagné, Bernard Têtu, Michèle Orain, Stéphane Turcotte, Marie Plante, Jean Grégoire, Marie-Claude Renaud, Isabelle Bairati, Dominique Trudel
Publikováno v:
Diagnostic Pathology, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Background The expression of high temperature requirement factor A1 (Htra1) has been reported to be decreased in ovarian carcinoma, but its prognostic effect remains undetermined. Methods We evaluated the impact of HtrA1 downregulation in tu
Externí odkaz:
https://doaj.org/article/a4a66144d0724d3c995194fecbb3cfc0
Autor:
Yohan Bossé, Andréanne Gagné, Wajd Althakfi, Michèle Orain, Pierre Olivier Fiset, Patrice Desmeules, Philippe Joubert
Publikováno v:
Human Pathology. 128:56-68
Prognostic stratification of patients surgically resected with invasive pulmonary adenocarcinoma must be improved. Previous studies reported that complex glandular patterns (CGPs), cribriform and fused gland growth patterns, are associated with unfav
Autor:
Marion Tonneau, Kim Phan, Cécile Low-Kam, Francis Dutil, Suzanne Kazandjian, Davy Vanderweyen, Justin Panasci, Julie Malo, François Coulombe, Arielle Elkrief, Wiam Belkaïd, Lisa Di Jorio, Michèle Orain, Nicole Bouchard, Thierry Muanza, Kam Kafi, Florent Chandelier, Philippe Joubert, Bertrand Routy
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Normand Blais, Wiam Belkaid, Andréanne Gagné, Philippe Joubert, Michèle Orain, Julie Malo, Florence Blais, Corentin Richard, Xavier Deschênes-Simard, François Ghiringhelli, Loïck Galland, Bertrand Routy, Lena Cvetkovic, Arielle Elkrief, Antoine Desilets, Marc-André Hamel
Publikováno v:
Thrombosis Research. 205:29-39
Venous thrombotic events (VTEs) are a frequent complication of non-small cell lung cancer (NSCLC) and are associated with increased morbidity. Immune checkpoint inhibitors (ICIs) are revolutionizing the management of NSCLC, but little is known about
Autor:
Sabine Elowe, Romain Villot, Yohan Bossé, Stéphane Gobeil, Mathieu Laplante, Inan Bakan, Venkata S. K. Manem, Frédérick A. Mallette, Danielle Caron, Jean-Christophe Bérubé, Steve Bilodeau, Romain Devillers, Yves Gélinas, Yan Coulombe, Laura Tribouillard, Jean-Sébastien Bérubé, Éma Duchesne, Jean-Yves Masson, Michèle Orain, Erlinda Fernández, Luciano Gama-Braga, Audrey Poirier, Karine Boulay, Andréanne Gagné, Philippe Joubert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
RAS proteins are GTPases that lie upstream of a signaling network impacting cell fate determination. How cells integrate RAS activity to balance proliferation and cellular senescence is still incompletely characterized. Here, we identify ZNF768 as a
Autor:
Mirette Hanna, Isabelle Dumas, Michèle Orain, Simon Jacob, Bernard Têtu, François Sanschagrin, Alexandre Bureau, Brigitte Poirier, Caroline Diorio
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183579 (2017)
Increased levels of pro-inflammatory markers and decreased levels of anti-inflammatory markers in the breast tissue can result in local inflammation. We aimed to investigate whether local inflammation in the breast tissue is associated with age-relat
Externí odkaz:
https://doaj.org/article/124f9fd5c23c4de4bcec67a6d124fe0d