Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michèle Granger-Schnarr"'
Publikováno v:
Protein Science. 7:512-515
The LexA protein is part of a large family of prokaryotic transcriptional repressors that contain an amino-terminal DNA binding domain and a carboxy-terminal dimerization domain. These domains are separated by a linker or hinge region, which is gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd20d4b7e94a980ed2e810ea85ccadc
https://doi.org/10.1002/pro.5560070234
https://doi.org/10.1002/pro.5560070234
Autor:
G Younès-Cauet, Michèle Granger-Schnarr, Pascale Oertel-Buchheit, Dominique Porte, Manfred Schnarr, M Dmitrova
Publikováno v:
Molecular and General Genetics MGG. 257:205-212
Interactions between proteins affect a wide variety of biological processes, such as signal transduction and control of gene expression. In order to facilitate the study of protein-protein interactions we have developed a new method for specifically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a006028f14255ed61e9a5710dc82b81e
https://doi.org/10.1007/s004380050640
https://doi.org/10.1007/s004380050640
Publikováno v:
Nucleic Acids Research. 25:3026-3033
The mammalian Fos and Fos-related proteins are unable to form homodimers and to bind DNA in the absence of a second protein, like c-Jun for example. In order to study the implications of hydrophobic point mutations in the c-Fox leucine zipper on DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137917820302f8f648da2c010cd72c07
https://doi.org/10.1093/nar/25.15.3026
https://doi.org/10.1093/nar/25.15.3026
Publikováno v:
Nucleic Acids Research. 24:4751-4758
cAMP-responsive-element (CRE)-binding factors interaction with nucleosomal DNA has been investigated in vitro on the human c-fos promoter. Analysis of nucleosome reconstitution of this promoter shows a preferential nucleosome positioning on the proxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e7a371bd997842e160b5d6c7c68da6
https://doi.org/10.1093/nar/24.23.4751
https://doi.org/10.1093/nar/24.23.4751
Publikováno v:
Nucleic Acids Research. 21:2363-2367
The LexA repressor from Escherichia coli induces DNA bending upon interaction with the two overlapping operators which regulate the transcription of the colicin A encoding gene caa. Both caa operators harbor T-tracts adjacent to their recognition mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3f3b231c2eb99a88d10c616fae16cd
https://doi.org/10.1093/nar/21.10.2363
https://doi.org/10.1093/nar/21.10.2363
Publikováno v:
Proceedings of the National Academy of Sciences. 89:4236-4239
Transcription factor c-Jun appears to be a nuclear target of the Ras-induced signal transduction pathway. In fact, some experiments show that transforming forms of the Ras protein cooperate with Jun in transcriptional activation mediated by an AP-1 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b1ec91160afe819fb8b540e6efb99b
https://doi.org/10.1073/pnas.89.10.4236
https://doi.org/10.1073/pnas.89.10.4236
Autor:
Robert Kaptein, Michèle Granger-Schnarr, Luigi Messori, Heinz Rüterjans, Manfred Schnarr, Gunnar Ottleben
Publikováno v:
Scopus-Elsevier
A synthetic half-operator DNA-duplex, d(GCTACTGTATGT), containing a portion of the proposed recognition sequence (CTGT) of several "SOS" genes, has been synthesized. The dodecamer has been characterized through 1H-NMR spectroscopy. Complete assignmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13165b130077ff0edeb402033c4404cf
https://doi.org/10.1080/07391102.1991.10507928
https://doi.org/10.1080/07391102.1991.10507928
Publikováno v:
Biochimie. 73:423-431
The LexA repressor from Escherichia coli negatively regulates the transcription of about 20 different genes upon binding with variable affinity to single-, double- or even triple-operators as in the case of the recN gene. Binding of LexA to multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac6618a414d614f0932717c0ee97b02
https://doi.org/10.1016/0300-9084(91)90109-e
https://doi.org/10.1016/0300-9084(91)90109-e
Publikováno v:
Molecular and General Genetics MGG. 223:40-48
We report the isolation of LexA mutant proteins with impaired repressor function. These mutant proteins were obtained by transforming a LexA-deficient recA-lacZ indicator strain with a randomly mutagenized plasmid harbouring the lexA gene and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f2615dc93a9462c7e7bad591a10e45
https://doi.org/10.1007/bf00315795
https://doi.org/10.1007/bf00315795
Publikováno v:
Methods in enzymology. 358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed964d43e374935724419edc9958c6cc
https://pubmed.ncbi.nlm.nih.gov/12474385
https://pubmed.ncbi.nlm.nih.gov/12474385