Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michèle Goodhardt"'
Autor:
Morgane Mabire, Pushpa Hegde, Adel Hammoutene, Jinghong Wan, Charles Caër, Rola Al Sayegh, Mathilde Cadoux, Manon Allaire, Emmanuel Weiss, Tristan Thibault-Sogorb, Olivier Lantz, Michèle Goodhardt, Valérie Paradis, Pierre de la Grange, Hélène Gilgenkrantz, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Liver cirrhosis is characterised by extensive fibrosis of the liver, and understanding the underpinning immunological processes is important in designing intervention. Here authors show that Mucosal-Associated Invariant T cells are instrumental to co
Externí odkaz:
https://doaj.org/article/49d8dca78ad94f9fac7e66da26a40cc1
Autor:
Kutaiba Alhaj Hussen, Emna Chabaane, Elisabeth Nelson, Shalva Lekiashvili, Samuel Diop, Seydou Keita, Bertrand Evrard, Aurélie Lardenois, Marc Delord, Els Verhoeyen, Kerstin Cornils, Zeinab Kasraian, Elizabeth A. Macintyre, Ana Cumano, David Garrick, Michele Goodhardt, Guillaume P. Andrieu, Vahid Asnafi, Frederic Chalmel, Bruno Canque
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107890- (2023)
Summary: The developmental cartography of human lymphopoiesis remains incompletely understood. Here, we establish a multimodal map demonstrating that lymphoid specification follows independent direct or stepwise hierarchic routes converging toward th
Externí odkaz:
https://doaj.org/article/06171025b16245b4bbab3a99462d5ce3
Autor:
Audrey Abecassis, Nathalie Roders, Maxime Fayon, Caroline Choisy, Elisabeth Nelson, Stephanie Harel, Bruno Royer, Camille Villesuzanne, Alexis Talbot, David Garrick, Michele Goodhardt, Jean‐Paul Fermand, Mike Burbridge, Bertrand Arnulf, Jean‐Christophe Bories
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 970-974 (2022)
Abstract Chimeric antigen receptor T cells (CAR‐T) have provided promising results in multiple myeloma (MM). However, many patients still relapse, pointing toward the need of improving this therapy. Here, we analyzed peripheral blood T cells from M
Externí odkaz:
https://doaj.org/article/338bcbe39cad4692acdfb83db0d67b2b
Autor:
Seydou Keita, Samuel Diop, Shalva Lekiashvili, Emna Chabaane, Elisabeth Nelson, Marion Strullu, Chloé Arfeuille, Fabien Guimiot, Thomas Domet, Sophie Duchez, Bertrand Evrard, Thomas Darde, Jerome Larghero, Els Verhoeyen, Ana Cumano, Elizabeth A. Macintyre, Zeinab Kasraian, François Jouen, Michele Goodhardt, David Garrick, Frederic Chalmel, Kutaiba Alhaj Hussen, Bruno Canque
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112618- (2023)
Summary: Changes in lymphocyte production patterns occurring across human ontogeny remain poorly defined. In this study, we demonstrate that human lymphopoiesis is supported by three waves of embryonic, fetal, and postnatal multi-lymphoid progenitors
Externí odkaz:
https://doaj.org/article/159f2d831f9a402db5b8c2adc8fa3349
Autor:
Renata Neves, Granito, Wafa, Bouleftour, Odile, Sabido, Chloé, Lescale, Mireille, Thomas, Jane E, Aubin, Michèle, Goodhardt, Laurence, Vico, Luc, Malaval
Publikováno v:
Journal of cellular physiology. 230(6)
Matrix proteins of the SIBLING family interact with bone cells, extracellular matrix and mineral and are thus in a key position to regulate the microenvironment of the bone tissue, including its hematopoietic component. In this respect, osteopontin (
Autor:
Eduardo Fernandez-Rebollo, Birgit Mentrup, Regina Ebert, Julia Franzen, Giulio Abagnale, Torsten Sieben, Alina Ostrowska, Per Hoffmann, Pierre-François Roux, Björn Rath, Michele Goodhardt, Jean-Marc Lemaitre, Oliver Bischof, Franz Jakob, Wolfgang Wagner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Culture medium of mesenchymal stromal cells (MSCs) is usually supplemented with either human platelet lysate (HPL) or fetal calf serum (FCS). Many studies have demonstrated that proliferation and cellular morphology are affected by these sup
Externí odkaz:
https://doaj.org/article/2212fb9151c240eb8164a2503a67027e
Autor:
Dounia Djeghloul, Klaudia Kuranda, Isabelle Kuzniak, Daniela Barbieri, Irina Naguibneva, Caroline Choisy, Jean-Christophe Bories, Christine Dosquet, Marika Pla, Valérie Vanneaux, Gérard Socié, Françoise Porteu, David Garrick, Michele Goodhardt
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 970-984 (2016)
Summary: The capacity of hematopoietic stem cells (HSC) to generate B lymphocytes declines with age, contributing to impaired immune function in the elderly. Here we show that the histone methyltransferase SUV39H1 plays an important role in human B l
Externí odkaz:
https://doaj.org/article/2bfd3069f5604216847aab88774cdd80