Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Michèle A Barocchi"'
Autor:
Monica Moschioni, Morena Lo Sapio, Giovanni Crisafulli, Giulia Torricelli, Silvia Guidotti, Alessandro Muzzi, Michèle A Barocchi, Claudio Donati
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61003 (2013)
Multi-Locus Sequence Typing (MLST) of Streptococcus pneumoniae is based on the sequence of seven housekeeping gene fragments. The analysis of MLST allelic profiles by eBURST allows the grouping of genetically related strains into Clonal Complexes (CC
Externí odkaz:
https://doaj.org/article/7d834516de0b4e5588f7cef37f867d01
Autor:
Marco Becherelli, Prachi Prachi, Elisa Viciani, Massimiliano Biagini, Luigi Fiaschi, Emiliano Chiarot, Sarah Nosari, Cecilia Brettoni, Sara Marchi, Marco Biancucci, Maria Rita Fontana, Francesca Montagnani, Fabio Bagnoli, Michèle A Barocchi, Andrea G O Manetti
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74718 (2013)
Staphylococcus aureus is an opportunistic pathogen, commensal of the human skin and nares, but also responsible for invasive nosocomial as well as community acquired infections. Staphylococcus aureus adheres to the host tissues by means of surface ad
Externí odkaz:
https://doaj.org/article/f5829010c3c34dde969e68d4f7c2ec6a
Autor:
Gabriella De Angelis, Monica Moschioni, Alessandro Muzzi, Alfredo Pezzicoli, Stefano Censini, Isabel Delany, Morena Lo Sapio, Antonia Sinisi, Claudio Donati, Vega Masignani, Michèle A Barocchi
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21269 (2011)
The Streptococcus pneumoniae pilus-1 is encoded by pilus islet 1 (PI-1), which has three clonal variants (clade I, II and III) and is present in about 30% of clinical pneumococcal isolates. In vitro and in vivo assays have demonstrated that pilus-1 i
Externí odkaz:
https://doaj.org/article/20870092183d407c86ed7e37e7bbcc0f
Autor:
Markus Hilleringmann, Fabiola Giusti, Barbara C Baudner, Vega Masignani, Antonello Covacci, Rino Rappuoli, Michèle A Barocchi, Ilaria Ferlenghi
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000026 (2008)
Pili have been identified on the cell surface of Streptococcus pneumoniae, a major cause of morbidity and mortality worldwide. In contrast to Gram-negative bacteria, little is known about the structure of native pili in Gram-positive species and thei
Externí odkaz:
https://doaj.org/article/afa7033223844b56ace88d4b3edfeb98
Autor:
Glen Spraggon, Eric Koesema, Maria Scarselli, Enrico Malito, Massimiliano Biagini, Nathalie Norais, Carla Emolo, Michèle Anne Barocchi, Fabiola Giusti, Markus Hilleringmann, Rino Rappuoli, Scott Lesley, Antonello Covacci, Vega Masignani, Ilaria Ferlenghi
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10919 (2010)
Streptococcus pneumoniae, like many other Gram-positive bacteria, assembles long filamentous pili on their surface through which they adhere to host cells. Pneumococcal pili are formed by a backbone, consisting of the repetition of the major componen
Externí odkaz:
https://doaj.org/article/656e18f1b5f0498888c53c2618bd2079
Autor:
Monica Moschioni, N. Kaewcharernnet, Claudia Turner, François Nosten, David Goldblatt, Paul Turner, Wanitda Watthanaworawit, Sara Melchiorre, Michèle A. Barocchi
Publikováno v:
Clinical Microbiology and Infection
Streptococcus pneumoniae pilus islet-1 (PI-1)-encoded pilus enhances in vitro adhesion to the respiratory epithelium and may contribute to pneumococcal nasopharyngeal colonization and transmission. The pilus subunits are regarded as potential protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791f17f6817f2d4e83e68627b30b6657
https://doi.org/10.1111/j.1469-0691.2011.03711.x
https://doi.org/10.1111/j.1469-0691.2011.03711.x
Publikováno v:
Science translational medicine. 8(345)
Vaccines have the potential to transform the health of all individuals and to reduce the health inequality between rich and poor countries. However, to achieve these goals, it is no longer sufficient to prioritize vaccine development using cost-effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025c06eb898bd5702633acd7daf2a977
https://pubmed.ncbi.nlm.nih.gov/27358496
https://pubmed.ncbi.nlm.nih.gov/27358496
Publikováno v:
Journal of Biotechnology. 157:279-286
Functional studies of Streptococcus pneumoniae virulence factors are facilitated by the development of complementation/mutagenesis systems. These methods usually result in poor expression yields; therefore, biochemical and structural/functional chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df2fe3ae488c4b74cd13c5e85a8c436
https://doi.org/10.1016/j.jbiotec.2011.11.011
https://doi.org/10.1016/j.jbiotec.2011.11.011
Autor:
Michèle A. Barocchi, Mariagrazia Pizza, Claudio Donati, Massimiliano Biagini, Silvia Maccari, Nathalie Norais, Werner Pansegrau, Carla Emolo, Monica Moschioni, Paolo Ruggiero, Markus Hilleringmann, Ilaria Ferlenghi, Antonia Sinisi, Vega Masignani
Publikováno v:
Infection and Immunity. 78:5033-5042
Thirty percent of Streptococcus pneumoniae isolates contain pilus islet 1, coding for a pilus composed of the backbone subunit RrgB and two ancillary proteins, RrgA and RrgC. RrgA is the major determinant of in vitro adhesion associated with pilus 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51f9c6e1279eb9228ddf359442b1952
https://doi.org/10.1128/iai.00601-10
https://doi.org/10.1128/iai.00601-10
Autor:
Monica Moschioni, G. De Angelis, Eugene Leibovitz, Michèle A. Barocchi, Vega Masignani, Sara Melchiorre, Ron Dagan
Publikováno v:
Clinical Microbiology and Infection. 16(9):1501-1504
We evaluated the distribution of the two known Streptococcus pneumoniae pilus encoding islets (PI-1 and PI-2) among a panel of 113 acute otitis media clinical isolates from Israel. PI-1 was present in 30.1% (n = 34) of the isolates tested, and PI-2 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec87a2aad7c6222fb909d2ce8cc056b