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Autor:
Garrett C. Reed, Ania Plonski, Micah Morris, Rahil Patel, Preet Patel, Whitney A. Richert, David L. Tierney, Zachary Higgins, Rithvik Venna, M. Sameer Al-Abdul-Wahid, Anthony Forchonie, Daniel T. DeGenova
Publikováno v:
Biophysical Journal. 110:153a
Carbonic anhydrase (CA) is being used as a model for matrix metalloproteinases (MMPs). CA is a more ubiquitous protein that binds zinc in the same manner as MMPs, His3(OH). Current MMP inhibitors target both unregulated and normal functioning MMPs at