Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Micah L Burch"'
Autor:
Ahrathy Selathurai, Greg M. Kowalski, Shaun A. Mason, Damien L. Callahan, Victoria C. Foletta, Paul A. Della Gatta, Angus Lindsay, Steven Hamley, Gunveen Kaur, Annie R. Curtis, Micah L. Burch, Teddy Ang, Sean L. McGee, Clinton R. Bruce
Publikováno v:
Molecular Metabolism, Vol 27, Iss , Pp 33-46 (2019)
Objective: Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mito
Externí odkaz:
https://doaj.org/article/014e06075bd9459593a0edd456e20e9c
Publikováno v:
The Scientific World Journal, Vol 11, Pp 709-714 (2011)
Seven transmembrane G protein—coupled receptors are among the most common in biology and they transduce cellular signals from a plethora of hormones. As well as their own well-characterized signaling pathways, they can also transactivate tyrosine k
Externí odkaz:
https://doaj.org/article/9a4e074e3f0547318a607f931f7d7e90
Autor:
Teddy Ang, Ahrathy Selathurai, Angus Lindsay, Victoria C. Foletta, Gunveen Kaur, Clinton R. Bruce, Sean L. McGee, Micah L Burch, Shaun A. Mason, Steven Hamley, Paul A. Della Gatta, Damien L. Callahan, Grzegorz M Kowalski, Annie R Curtis
Publikováno v:
Molecular Metabolism, Vol 27, Iss, Pp 33-46 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d48d5b907b2317df0cc50f55e04300
http://www.sciencedirect.com/science/article/pii/S2212877819302698
http://www.sciencedirect.com/science/article/pii/S2212877819302698
Autor:
Kenshi Hayashi, Aparna Mahadevan, Wandi Zhu, Calum A. MacRae, Tuomas Kiviniemi, E. Buys, Micah L Burch, Wei Dai, Jing Liu, Ryota Teramoto, Manu Beerens, Ashmita Kc, David Y. Chiang, Masahiro Satoh
Publikováno v:
Circulation. 142
Introduction: Mutations in the lamin A/C ( LMNA ) gene have been causally linked to atrial arrhythmias and cardiac conduction disease (CCD) in young adults. However, the mechanism by which the laminopathy leads to perturbed cardiac electrophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e258d7922cbb20c4ce93479fc5b1ce
https://doi.org/10.1161/circ.142.suppl_3.16184
https://doi.org/10.1161/circ.142.suppl_3.16184
Autor:
Wenhua Zheng, Morley D. Hollenberg, Robel Getachew, Micah L Burch, Lyna Thach, Narin Osman, Danielle Kamato, Peter J. Little
Publikováno v:
Cellular Signalling. 28:110-119
G protein-coupled receptors (GPCR) are one of the most important targets for therapeutics due to their abundance and diversity. The G protein-coupled receptor for thrombin can transactivate protein tyrosine kinase receptors (PTKR) and we have recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf9252f5589c1675580842d3afc6b34
https://doi.org/10.1016/j.cellsig.2015.11.003
https://doi.org/10.1016/j.cellsig.2015.11.003
Autor:
Kenshi Hayashi, Manu Beerens, Yao Zu, E. Buys, Micah L Burch, Calum A. MacRae, Tuomas Kiviniemi, Ryota Teramoto, Akihiro Nomura, Aaron P. Kithcart, Masayuki Takamura, David Y. Chiang
Publikováno v:
Journal of the American College of Cardiology. 75:703
Mutations in the lamin A/C ( LMNA ) gene have been causally linked to dilated cardiomyopathy with conduction disease. However, the mechanism by which the laminopathy leads to electrophysiological disorders has not been fully elucidated. In a multi-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3372d9193862ba21fcfeef0bbefec4f
https://doi.org/10.1016/s0735-1097(20)31330-9
https://doi.org/10.1016/s0735-1097(20)31330-9
Autor:
Ying Zhou, Raafat Mohamed, Micah L Burch, Danielle Kamato, Wenhua Zheng, Narin Osman, Jennifer L. Stow, Peter J. Little
Publikováno v:
Cellular signalling. 53
Growth factors such as thrombin and transforming growth factor (TGF)-β facilitate glycosaminoglycan (GAG) chain hyperelongation on proteoglycans, a phenomenon that increases lipoprotein binding in the vessel wall and the development of atheroscleros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1203c47d894a62bf8a03ddfde54847bc
https://pubmed.ncbi.nlm.nih.gov/30423352
https://pubmed.ncbi.nlm.nih.gov/30423352
Autor:
Joachim Kloehn, Malcolm J. McConville, Ahrathy Selathurai, Stephanie A.M. Bayol, Séverine Lamon, Robert S. Lee-Young, Matthew J. Watt, Grzegorz M Kowalski, Micah L Burch, Clinton R. Bruce, Steven Hamley
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1851:210-219
Hepatic insulin resistance is a major risk factor for the development of type 2 diabetes and is associated with the accumulation of lipids, including diacylglycerol (DAG), triacylglycerols (TAG) and ceramide. There is evidence that enzymes involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803cf39e4e6a9be4431c52fbf4e4acaf
https://doi.org/10.1016/j.bbalip.2014.12.002
https://doi.org/10.1016/j.bbalip.2014.12.002
Autor:
Graeme I. Lancaster, Wenhua Zheng, Peter J. Little, Micah L Burch, Rikang Wang, Haitau Wang, Robel Getachew, Narin Osman
Publikováno v:
Growth Factors. 29:203-210
Transforming growth factor-β (TGF-β) can mediate proteoglycan synthesis via Smad and non-Smad signalling pathways in vascular smooth muscle (VSM). We investigated whether TGF-β-mediated proteoglycan synthesis is via PI3K/Akt. TGF-β induced a rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d3def3d326904b00d146b8164b858c
https://doi.org/10.3109/08977194.2011.615747
https://doi.org/10.3109/08977194.2011.615747
Autor:
Micah L Burch, Peter J. Little, Sundy N Y Yang, Lisa R. Tannock, Stephen P. Evanko, Narin Osman
Publikováno v:
Journal of Diabetes. 2:233-242
Atherosclerosis is accelerated in the setting of diabetes, but the factors driving this phenomenon remain elusive. Hyperglycemia leads to elevated levels of transforming growth factor (TGF)-β and TGF-β has been implicated as a factor in atheroscler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48f254731015e708cced1d33b6bc1196
https://doi.org/10.1111/j.1753-0407.2010.00089.x
https://doi.org/10.1111/j.1753-0407.2010.00089.x