Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Micah Dembo"'
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 1, p e1001068 (2011)
Encounters between human neutrophils and zymosan elicit an initially protrusive cell response that is distinct from the thin lamella embracing antibody-coated targets. Recent experiments have led us to hypothesize that this behavior has its mechanist
Externí odkaz:
https://doaj.org/article/8684fbb905e24274b51c7ec07cd0940a
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10082 (2010)
The transport of labeled G-actin from the mid-lamella region to the leading edge in a highly motile malignant rat fibroblast line has been studied using fluorescence localization after photobleaching or FLAP, and the transit times recorded in these e
Externí odkaz:
https://doaj.org/article/8807adb029504161a6f7304a61843f75
Publikováno v:
Cellular and Molecular Bioengineering. 9:455-465
Macrophages become polarized by cues in their environment and this polarization causes a functional change in their behavior. Two main subsets of polarized macrophages have been described. M1, or “classically activated” macrophages, are pro-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed09bf9f032cd61f38065fdf9672f206
https://doi.org/10.1007/s12195-016-0435-x
https://doi.org/10.1007/s12195-016-0435-x
Autor:
Micah Dembo, Marc Herant
Publikováno v:
Biorheology. 52:405-414
BACKGROUND: The processes of cell spreading and crawling are frequently associated with mysterious waves and ruffling cycles of the leading edge. OBJECTIVE: To develop a physical model that can account for these phenomena based on a few simple and pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6ae6d40637986068a4ba6e2ecd92f6
https://doi.org/10.3233/bir-14042
https://doi.org/10.3233/bir-14042
Publikováno v:
Biophysical Journal. 110(3)
We have developed a method to understand the forces that pairs of cells exert upon each other on a surface. When exerting a force or torque on another object, a cell experiences an equal and opposite recoil force, and must therefore brace itself agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb9934e890a6efb31e2bb88b7be38a7
Publikováno v:
Biophysical Journal. 101:575-584
Proper functioning of the innate immune response depends on migration of circulating neutrophils into tissues at sites of infection and inflammation. Migration of highly motile, amoeboid cells such as neutrophils has significant physiological relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8544521e498a238dab07a07aedc061fe
https://doi.org/10.1016/j.bpj.2011.05.040
https://doi.org/10.1016/j.bpj.2011.05.040
Autor:
Micah Dembo, Marc Herant
Publikováno v:
Journal of Computational Biology. 17:1639-1677
When cultured on flat surfaces, fibroblasts and many other cells spread to form thin lamellar sheets. Motion then occurs by extension of the sheet at the leading edge and retraction at the trailing edge. Comprehensive quantitative models of these phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389da64b59f425646d3bd97244f58704
https://doi.org/10.1089/cmb.2009.0271
https://doi.org/10.1089/cmb.2009.0271
Autor:
Micah Dembo, Marc Herant
Publikováno v:
Biophysical Journal. 98(8):1408-1417
It is plain enough that a horse is made for running, but similar statements about motile cells are not so obvious. Here the basis for structure-function relations in cell motility is explored by application of a new computational technique that allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0b725192f642cc836eddd5d0a30cdc
Autor:
Leann L. Norman, Fitzroy J. Byfield, Irena Levitan, Ratna J. Oetama, Daniel A. Hammer, Helim Aranda-Espinoza, Micah Dembo
Publikováno v:
Cellular and Molecular Bioengineering. 3:151-162
Cellular cholesterol is a critical component of the plasma membrane, and plays a key role in determining the physical properties of the lipid bilayer, such as elasticity, viscosity, and permeability. Surprisingly, it has been shown that cholesterol d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613f997370bb567ed44d265e224c2974
https://doi.org/10.1007/s12195-010-0119-x
https://doi.org/10.1007/s12195-010-0119-x
Autor:
Micah Dembo, Peter A. Greer, Benjamin J. Perrin, Karen A. Beningo, Katherine M. Cembrola, Yu Ii Wang, Vishnu V Undyala, Anna Huttenlocher, John S. Elce
Publikováno v:
Journal of Cell Science. 121:3581-3588
Cell migration involves the dynamic formation and release of cell-substrate adhesions, where the exertion and detection of mechanical forces take place. Members of the calpain family of calcium-dependent proteases are believed to have a central role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425a0f5ccf7b4f8beefdb35bd43449ee
https://doi.org/10.1242/jcs.036152
https://doi.org/10.1242/jcs.036152