Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Micaela G. Fosdick"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Glycerol monolaurate (GML) is a naturally occurring antimicrobial agent used commercially in numerous products and food items. GML is also used as a homeopathic agent and is being clinically tested to treat several human diseases. In additio
Externí odkaz:
https://doaj.org/article/654d8d0b3ead4a838e4c1eb63b5d123e
Autor:
Micaela G. Fosdick, Pratik Rajesh Chheda, Phuong M. Tran, Alex Wolff, Ronal Peralta, Michael Y. Zhang, Robert Kerns, Jon C. D. Houtman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glycerol monolaurate (GML), a naturally occurring monoglyceride, is widely used commercially for its antimicrobial properties. Interestingly, several studies have shown that GML not only has antimicrobial properties but is also an anti-infla
Externí odkaz:
https://doaj.org/article/3f0a0641182b469a9ee320d86e8250d8
Autor:
Isaac J Jensen, Xiang Li, Patrick W McGonagill, Qiang Shan, Micaela G Fosdick, Mikaela M Tremblay, Jon CD Houtman, Hai-Hui Xue, Thomas S Griffith, Weiqun Peng, Vladimir P Badovinac
Publikováno v:
eLife, Vol 10 (2021)
The global health burden due to sepsis and the associated cytokine storm is substantial. While early intervention has improved survival during the cytokine storm, those that survive can enter a state of chronic immunoparalysis defined by transient ly
Externí odkaz:
https://doaj.org/article/96b44fa8eb9b49b08945650bd27d9fdc
Autor:
Isaac J Jensen, Christina S Winborn, Micaela G Fosdick, Peng Shao, Mikaela M Tremblay, Qiang Shan, Sandeep Kumar Tripathy, Christopher M Snyder, Hai-Hui Xue, Thomas S Griffith, Jon C Houtman, Vladimir P Badovinac
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007405 (2018)
The sepsis-induced cytokine storm leads to severe lymphopenia and reduced effector capacity of remaining/surviving cells. This results in a prolonged state of immunoparalysis, that contributes to enhanced morbidity/mortality of sepsis survivors upon
Externí odkaz:
https://doaj.org/article/03b923b0ce134deaa8ed4995b5e1b679
Autor:
Mikaela M. Tremblay, Isaac J. Jensen, Thomas S. Griffith, Weiqun Peng, Micaela G. Fosdick, Qiang Shan, Vladimir P. Badovinac, Xiang Li, Jon C. D. Houtman, Patrick W. McGonagill, Hai-Hui Xue
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
The global health burden due to sepsis and the associated cytokine storm is substantial. While early intervention has improved survival during the cytokine storm, those that survive can enter a state of chronic immunoparalysis defined by transient ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07614db11ee571b390cc7235daa6418e
http://europepmc.org/articles/PMC8589447
http://europepmc.org/articles/PMC8589447
Autor:
Thomas S. Griffith, Weiqun Peng, Micaela G. Fosdick, Jon C. D. Houtman, Vladimir P. Badovinac, Xiang Li, Qiang Shan, Isaac J. Jensen, Mikaela M. Tremblay, Patrick W. McGonagill, Hai-Hui Xue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f54d28914e7f61ce39c3c1588d9fd8
https://doi.org/10.7554/elife.70989.sa2
https://doi.org/10.7554/elife.70989.sa2
Autor:
Michael Y. Zhang, Micaela G. Fosdick, Pratik Rajesh Chheda, Jon C. D. Houtman, Alex Wolff, Phuong M. Tran, Ronal Peralta, Robert J. Kerns
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Glycerol monolaurate (GML), a naturally occurring monoglyceride, is widely used commercially for its antimicrobial properties. Interestingly, several studies have shown that GML not only has antimicrobial properties but is also an anti-inflammatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe6c23a749731d1c9a16316fa88bd00
https://doi.org/10.1038/s41598-021-88584-y
https://doi.org/10.1038/s41598-021-88584-y
Autor:
John M. Buatti, Micaela G. Fosdick, Casey F. Pulliam, Sarah L. Mott, Garry R. Buettner, Aaron D. Bossler, Melissa A. Fath, Douglas R. Spitz, Stacey M. Hartwig, Bryan G. Allen, Brett A. Wagner, Jon C. D. Houtman, Michael S. Petronek, Mikaela M. Tremblay, Kellie L. Bodeker, Varun Monga, Taher Abu-Hejleh, Brian J. Smith, Jun Zhang, Andrew M. Bellizzi, Joseph J. Cullen, Hariharasudan Mani, Muhammad Furqan, Steven M. Varga, Laura M. Pietrok
Publikováno v:
Cancer Research. 81:CT164-CT164
PURPOSE: First line treatment with platinum-based chemotherapy with or without immunotherapy improves survival in metastatic non-small cell lung cancer (NSCLC). Preclinical studies suggest that pharmacological ascorbate (P-AscH-) enhances tumor respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d4fb12fdf2db8764a8a4b4cf032bf5
https://doi.org/10.1158/1538-7445.am2021-ct164
https://doi.org/10.1158/1538-7445.am2021-ct164
Autor:
Christina S. Winborn, Thomas S. Griffith, Mikaela M. Tremblay, Christopher M. Snyder, Sandeep K. Tripathy, Qiang Shan, Micaela G. Fosdick, Hai-Hui Xue, Peng Shao, Jon C. D. Houtman, Isaac J. Jensen, Vladimir P. Badovinac
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007405 (2018)
PLoS Pathogens, Vol 14, Iss 10, p e1007405 (2018)
The sepsis-induced cytokine storm leads to severe lymphopenia and reduced effector capacity of remaining/surviving cells. This results in a prolonged state of immunoparalysis, that contributes to enhanced morbidity/mortality of sepsis survivors upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122ae43542847f7b6241834dcf44ea5d
https://pubmed.ncbi.nlm.nih.gov/30379932
https://pubmed.ncbi.nlm.nih.gov/30379932
Autor:
Phuong M. Tran, Micaela G. Fosdick, Alexander J. Wolff, Mikaela M. Tremblay, Jon C. D. Houtman, Michael S. Zhang
Publikováno v:
Science Signaling. 11
Glycerol monolaurate (GML) is a monoglyceride with potent antimicrobial properties that suppresses T cell receptor (TCR)-induced signaling and T cell effector function. Actin rearrangement is needed for the interaction of T cells with antigen-present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fe60cd69852dacd6e68c51557af758
https://doi.org/10.1126/scisignal.aam9095
https://doi.org/10.1126/scisignal.aam9095