Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Micaël, Carrier"'
Autor:
Micaël Carrier, Marie-Ève Robert, Marie-Kim St-Pierre, Fernando González Ibáñez, Elisa Gonçalves de Andrade, Audrée Laroche, Katherine Picard, Haley A. Vecchiarelli, Julie C. Savage, Éric Boilard, Michèle Desjardins, Marie-Ève Tremblay
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110037- (2024)
Summary: Although the roles of embryonic yolk sac-derived, resident microglia in neurodevelopment were extensively studied, the possible involvement of bone marrow-derived cells remains elusive. In this work, we used a fate-mapping strategy to select
Externí odkaz:
https://doaj.org/article/bf4a91ff75b7430f937daad11da42e1d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The central nervous system (CNS) is an essential hub for neuronal communication. As a major component of the CNS, glial cells are vital in the maintenance and regulation of neuronal network dynamics. Research on microglia, the resident innate immune
Externí odkaz:
https://doaj.org/article/66f3fb9f88414c6595f6e02df0c2a679
Autor:
Moises Freitas-Andrade, Cesar H. Comin, Peter Van Dyken, Julie Ouellette, Joanna Raman-Nair, Nicole Blakeley, Qing Yan Liu, Sonia Leclerc, Youlian Pan, Ziying Liu, Micaël Carrier, Karan Thakur, Alexandre Savard, Gareth M. Rurak, Marie-Ève Tremblay, Natalina Salmaso, Luciano da F. Costa, Gianfilippo Coppola, Baptiste Lacoste
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Astrocytes are intimately linked with brain blood vessels, an essential relationship for neuronal function. However, astroglial factors driving these physical and functional associations during postnatal brain development have yet to be iden
Externí odkaz:
https://doaj.org/article/1444d2869d174be7aedff420c23cde27
Autor:
Marie-Kim St-Pierre, Micaël Carrier, Fernando González Ibáñez, Mohammadparsa Khakpour, Marie-Josée Wallman, Martin Parent, Marie-Ève Tremblay
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-27 (2023)
Abstract The past decade has witnessed increasing evidence for a crucial role played by glial cells, notably astrocytes, in Alzheimer’s disease (AD). To provide novel insights into the roles of astrocytes in the pathophysiology of AD, we performed
Externí odkaz:
https://doaj.org/article/20307c08ad6b4ccb9ba82d74e2a7f672
Autor:
Marie-Kim St-Pierre, Micaël Carrier, Fernando González Ibáñez, Eva Šimončičová, Marie-Josée Wallman, Luc Vallières, Martin Parent, Marie-Ève Tremblay
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-22 (2022)
Abstract A diverse heterogeneity of microglial cells was previously described in Alzheimer’s disease (AD) pathology, including dark microglia, a state characterized by ultrastructural markers of cellular stress. To provide novel insights into the r
Externí odkaz:
https://doaj.org/article/49c48042062d4eb0a0040c4b24fcd39b
Autor:
Benneth Ben-Azu, Elisabetta C. del Re, Jared VanderZwaag, Micaël Carrier, Matcheri Keshavan, Mohammadparsa Khakpour, Marie-Ève Tremblay
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Brain aging, which involves a progressive loss of neuronal functions, has been reported to be premature in probands affected by schizophrenia (SCZ). Evidence shows that SCZ and accelerated aging are linked to changes in epigenetic clocks. Recent cros
Externí odkaz:
https://doaj.org/article/94de1b38e6b9453fa9a9afc9c176bc4e
Autor:
Alexandria Béland-Millar, Alexia Kirby, Yen Truong, Julie Ouellette, Sozerko Yandiev, Khalil Bouyakdan, Chantal Pileggi, Shama Naz, Melissa Yin, Micaël Carrier, Pavel Kotchetkov, Marie-Kim St-Pierre, Marie-Ève Tremblay, Julien Courchet, Mary-Ellen Harper, Thierry Alquier, Claude Messier, Adam J. Shuhendler, Baptiste Lacoste
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112485- (2023)
Summary: Neurovascular abnormalities in mouse models of 16p11.2 deletion autism syndrome are reminiscent of alterations reported in murine models of glucose transporter deficiency, including reduced brain angiogenesis and behavioral alterations. Yet,
Externí odkaz:
https://doaj.org/article/80b98b8bcdd8414481360ac28e85ff5a
Autor:
Paul R Fortin, Marie-Ève Tremblay, Eric Boilard, Matthias Gunzer, Isabelle Allaeys, Tania Levesque, Louis Flamand, Audrée Laroche, Micaël Carrier, Denis Soulet, Marc Bazin, Nicolas Vallières, Steve Lacroix
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/071daa2899ca4b979eb7062e5be3f225
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
In the central nervous system (CNS) neurons are classically considered the functional unit of the brain. Analysis of the physical connections and co-activation of neurons, referred to as structural and functional connectivity, respectively, is a metr
Externí odkaz:
https://doaj.org/article/db485254343e468aa30fdb1a9b6a8bfc
Autor:
Julie C. Savage, Marie-Kim St-Pierre, Micaël Carrier, Hassan El Hajj, Sammy Weiser Novak, Maria Gabriela Sanchez, Francesca Cicchetti, Marie-Ève Tremblay
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder that affects cognitive and motor abilities by primarily targeting the striatum and cerebral cortex. HD is caused by a mutation elongating the CAG rep
Externí odkaz:
https://doaj.org/article/d4c9d594d21444658d6b9092d1971a10