Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miaoyi Wang"'
Autor:
Emily H. Pilkington, Yanting Xing, Bo Wang, Aleksandr Kakinen, Miaoyi Wang, Thomas P. Davis, Feng Ding, Pu Chun Ke
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Aggregation of islet amyloid polypeptide (IAPP), a peptide hormone co-synthesized and co-stored with insulin in pancreatic cells and also co-secreted to the circulation, is associated with beta-cell death in type-2 diabetes (T2D). In T2D pat
Externí odkaz:
https://doaj.org/article/eaaee3cf9e0345d29278a7ad9b05f984
Autor:
Emily H. Pilkington, Ava Faridi, Thomas P. Davis, Aleksandr Kakinen, Ove J. R. Gustafsson, Ibrahim Javed, Pu Chun Ke, Miaoyi Wang
Publikováno v:
Journal of materials chemistry. B. 6(38)
The protein corona is a concept central to a range of disciplines exploiting the bio–nano interface. As the literature continues to expand in this field, it is essential to condense and contextualize the in vitro and in vivo proteome databases accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4347d394399f980474f5d599f2759b4
https://pubmed.ncbi.nlm.nih.gov/32254813
https://pubmed.ncbi.nlm.nih.gov/32254813
Publikováno v:
2019 IEEE 5th International Conference on Computer and Communications (ICCC).
In this paper, we propose a novel three-dimensional (3D) geometry-based massive multiple-input multiple-output (MIMO) channel model for vehicle-to-vehicle (V2V) communication systems. Combining with the two-ring model and the semi-ellipsoid model, ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c90f2ea72f5e3dc9fc2f9e150fd14f9
https://doi.org/10.1109/iccc47050.2019.9064463
https://doi.org/10.1109/iccc47050.2019.9064463
Autor:
Darren J. Creek, Thomas P. Davis, Ove J. R. Gustafsson, Hannah G. Kelly, Ghizal Siddiqui, Hong Yin, Thomas Blin, Kristian Kempe, Stephen J. Kent, Pu Chun Ke, Miaoyi Wang, Ibrahim Javed
Publikováno v:
Nanoscale. 10:10863-10875
Polyethylene glycol (PEG) is a gold standard against protein fouling. However, recent studies have revealed surprising adverse effects of PEG, namely its immunogenicity and shortened bio-circulation upon repeated dosing. This highlights a crucial nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d785e5ab86ac88468252779d431935c
https://doi.org/10.1039/c8nr00835c
https://doi.org/10.1039/c8nr00835c
Autor:
Emily H. Pilkington, Bo Wang, Marc-Antonie Sani, Michael Whittaker, Thomas P. Davis, Xinwei Ge, Feng Ding, May Lai, William J Stanley, Pu Chun Ke, John Jf Quinn, Aleksandr Kakinen, Esteban Nicolas Gurzov, Miaoyi Wang
Publikováno v:
Biomacromolecules
Protein aggregation into amyloid fibrils is a ubiquitous phenomenon across the spectrum of neurodegenerative disorders and type 2 diabetes. A common strategy against amyloidogenesis is to minimize the populations of toxic oligomers and protofibrils b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0c9fe281e89412eafb64924900a6b0
http://europepmc.org/articles/PMC5729549
http://europepmc.org/articles/PMC5729549
Autor:
Thomas P. Davis, Yanting Xing, Emily H. Pilkington, Pu Chun Ke, Cameron J. Nowell, Yunxiang Sun, Miaoyi Wang, Aleksandr Kakinen, Feng Ding, Bo Wang
Publikováno v:
Physical Chemistry Chemical Physics. 19:30627-30635
Amyloid aggregation of human islet amyloid polypeptide (IAPP) is a hallmark of type 2 diabetes (T2D), a metabolic disease and a global epidemic. Although IAPP is synthesized in pancreatic β-cells, its fibrils and plaques are found in the extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8494027ea3759e2f4ce53852478414f2
https://doi.org/10.1039/c7cp06670h
https://doi.org/10.1039/c7cp06670h
Autor:
MIAOYI WANG
The interaction between nanoparticles and proteins dictates the ultimate biological fate of nanoparticles introduced in vivo and thus necessitates an in-depth examination for advancing nanomedicine. This thesis delineates plasma protein associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::501f43c64f1469077b0f37aa5a5237d9
Autor:
Yunxiang Sun, Miaoyi Wang, Feng Ding, Thomas P. Davis, Aleksandr Kakinen, Xueying Cao, Jingquan Liu, Sijie Lin, Ibrahim Javed, Pu Chun Ke, Guotao Peng
Publikováno v:
Nanoscale. 10(42)
The development of biocompatible nanomaterials has become a new frontier in the detection, treatment and prevention of human amyloid diseases. Here we demonstrated the use of graphene quantum dots (GQDs) as a potent inhibitor against the in vivo aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c908ebcb527f7f43178f38be8aa1966
https://pubmed.ncbi.nlm.nih.gov/30350837
https://pubmed.ncbi.nlm.nih.gov/30350837
Autor:
John D. Perry, David E. Hibbs, Miaoyi Wang, Ramesh R. Mamidi, Jia Lin Luo, Paul W. Groundwater, Linda Váradi
Publikováno v:
Bioorganicmedicinal chemistry. 26(16)
A novel, green fluorescent β-alanylstyrylcoumarin derivative was synthesized and evaluated for its performance as a fluorogenic enzyme substrate on a range of clinically relevant microorganisms. The substrate was selectively hydrolysed by β-alanyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d88aa0efa651e606dd13eda9aa8c42
https://pubmed.ncbi.nlm.nih.gov/30122283
https://pubmed.ncbi.nlm.nih.gov/30122283
Publikováno v:
Biomaterials science. 5(3)
Recent studies have shown promise on the use of small molecules and nanoparticles (NPs) for the inhibition of protein aggregation, a hallmark of neurodegenerative diseases and type 2 diabetes (T2D). Towards this end here we show the differential effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c32f87a2d738775e688eaac1ec206b
https://pubmed.ncbi.nlm.nih.gov/28078343
https://pubmed.ncbi.nlm.nih.gov/28078343